wabmester Member

Different for everybody. Experiment with your intake and find out what works for you. I've been in maintenance for about 9 months now and just eat to satiety. No calorie counting, no carb counting, just lowish carb and appetite-driven. Weight has been stable. No idea if I've undergone any "metabolic adaptation," but my…

I think the price is part of the punishment. :)

Does that include sodium? If so, that would explain a lot. Sodium deficiencies will cause problems alone, but left unaddressed, you'll end up deficient in potassium and other minerals.

If he's just going on levels of uric acid in your blood, then yeah, that's just a keto thing. If he tested the fluid in your joint for uric acid *crystals*, then that would suggest gout.

Never heard of a connection, but google has. http://www.livestrong.com/article/397774-insufficient-carb-intake-and-anxiety/ According to a case study by Mitali Wadekar, M.D., insufficient carb intake also leads to insufficient intake of tryptophan. Tryptophan is an amino acid used to make serotonin, a neurotransmitter…

@ladipoet, keto is a special case. Not so much because of the protein consumed, but more due to ketones competing with uric acid in the kidney's control of acid-base balance. Blame the ketones.

Ouch. It's not common, but if he's prone to gout attacks, it can trigger it. Keto causes uric acid levels to rise in the blood. Eating carbs causes it to drop back down. Supposedly, it's the change in level that acts as a trigger, so consistency in carb intake might be the best defense. It can take months for levels to…

Not that you have to worry about it that much, but yes, a reduction in carbs would more than offset an increase in protein.

The paper hasn't been published yet, but they used indirect calorimetry. They calculate EE from O2 consumed and CO2 exhausted. As Dr; Eades pointed out, we don't know if they included ketones lost in the urine, for example. They do collect urine, but I think it's mostly for nitrogen analysis to determine protein balance.…

Dumb is my specialty! Didn't look terribly interesting. Diabetes = high blood sugar. That can be due to poor glucose uptake, poor insulin sensitivity, or too little insulin secretion. This only considers the latter. If you're hypersensitive to melatonin, you'll suppress insulin production too much. It apparently requires…

And now a response from Ludwig: https://medium.com/@davidludwigmd/defense-of-the-insulin-carbohydrate-model-redux-a-response-to-kevin-hall-37ea64907257#.1efidk90s

Assuming that's all he ate: Calories: 1950 Protein: 150g Carbs: 15g Fat: 125g So very ketogenic. Didn't seem to help with his Alz, though.

No idea about the device, but food and exercise both have an effect. This will give you an idea of the relationship: Eating just about anything will quickly bring down the level of ketones.

Yup, a male athlete will have a lot of muscle glycogen. But how is that depleted? It's not available for "general" use. It's localized to the muscle and used for anaerobic metabolism. So it won't be depleted by simply restricting carbs. And when muscle glycogen is depleted (via anaerobic exercise), it's restored at rest.…

Here's a fun statistic for you: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139817 1797 patients were included from 17 trials.... The probability of greater weight loss associated with low carbohydrate was >99% while the reduction in predicted risk favoring low carbohydrate was >98%. 99% lost more…

I once calculated the ratio at around 360:1 (assuming blood volume adjusts to maintain 140 mmol/l). So a loss of 10g (after a week) = 8 lbs.

I assumed it was due to reduced leptin levels, but the few studies I looked at found no association with leptin levels and RMR. Even leptin replacement therapy didn't seem to change RMR according to studies, but I've heard (from one of the study participants) that it helped. It's a good question, though. I'll let you know…

There are estimations for converting between VO2 and HR, but they're just estimates. I simply use the "breathe through the nose test". If you can breathe through your nose while you run, you're probably still in the aerobic zone. For me (54 yo), that maxes out around 140-150 bpm.

Not wrong, just not very significant. Liver stores maybe 70-100g of glycogen, so the total water weight due to glycogen loss/gain is about 400g. Less than 1 lb. It's mostly sodium. It depends on your level of carb intake, but usually 1-2 days after you start. Starting right away wouldn't hurt.

Oops, you're right on CO2. I was thinking it would be conserved to build bicarbonate buffer. https://en.wikipedia.org/wiki/Bicarbonate 70–75% of CO2 in the body is converted into carbonic acid (H2CO3), which can quickly turn into bicarbonate.

It's a spectrum, as that definition I referenced shows. As you say, ketones are acids, and your body has to respond to the acid load, even at lower concentrations typical of nutritional ketosis. But I would think respiratory compensation would mostly kick in during alkalosis, not acidosis. Increased respiration would…

1 day of high carb would be sufficient to reload glycogen stores, knock you out of ketosis, and start retaining sodium again. It's the sodium retention that causes most of the water gain. It usually takes 4 days or so to lose the sodium/water once you deplete glycogen (which takes maybe 2 days), so 6 days would be about…

Probably a good test then. Read that study if you want to be convinced your heart rate can go much higher and still stay in the fat-burning zone now that you're low carb. :)

Ketoacids do get buffered in an effort to maintain blood pH. The degree of acidosis depends on the level of ketones and the degree of buffer exhaustion. Levels are defined here: http://emedicine.medscape.com/article/118361-workup While definitions vary, mild DKA can be categorized by a pH level of 7.25-7.3 and a serum…

How soon after the run did you test? The rise in glucose happens during exercise recovery. Metabolic characteristics of keto-adapted ultra-endurance runners Graph A shows you need to wait about an hour after the run.

Another good article published by an obesity doc today: I'm an obesity doctor. I've seen long-term weight loss work. Here's how. The key to your success is actually liking the life and diet you're living with while you're losing weight

How about "jogging is mind-boggling good for you." Hmm. Might need an xl shirt. :)

Dog food! When I started, my goal was to simply reduce my 10-year heart disease risk by fixing some risk markers (esp HDL and TG). That didn't take long. So the goal morphed into feeling good, not getting tuckered out doing yard work, and maintaining the unexpected benefits like improved skin, and other signs of good…

The second paper in the talk: Effects of Running on Chronic Diseases and Cardiovascular and All-Cause Mortality

I'm not saying the guy in the video is wrong, but his rubber band didn't convince me. :) What do we know about low carb? We know it takes a few days to adapt, so that alone is a pretty good argument to not cycle carbs. But there's also an appetite reduction effect (at least for many of us). Why is that? We know insulin is…