I'm on 25 mgs twice a day. This is totally unconfirmed because I haven't had a followup appt with the doctor yet, but it seems like it runs through your system pretty fast, so you need those two doses. Or maybe I do because its so low. I've been taking it for about 6 months now and around the three month mark I would have said it slowed facial hair growth and cleared up a little acne. Now at six months, I'm not so sure. But I have been missing doses on accident and started eating sugar again (stupid holidays! stupid summer!), so I'm redoubling my efforts to be good and will reassess in a few months. No side effects that I've noticed.