The cream was miserable for me. Every month I had 99% of pregnancy symptoms without the benefits of pregnancy. Plus, I had an undiagnosed/unconfirmed adrenal fatigue/cortisol deficiency, so since those are priority hormones, any progesterone I added was "stolen" and "converted" for use in those categories, so my underlying issues did not resolve. Not until years later.

So I would ensure that you've hit all the tests (I had to do a bunch of saliva tests, too, and stuff, it was a PAIN!) before agreeing to supplementation. So the cream absorbed well, but there were many unwanted side effects - and it didn't do what it was supposed to because of other conditions. Aside from that, I think that I'd see what your insurance will cover and experiment with whichever works better for you.

You might look into adding or increasing doses on more natural balancing agents like Inositol and Vitex. They might help more naturally.

I take 400mg a day of prometrium in my TWW. I don't really notice many side effects since I'm already in my luteal phase and my progesterone would be elevated anyway. Except that it could be making me tired. Like stupid tired. But I'm not sure if it's the prometrium, or if I'm normally that tired in my Clomid TWW's without the prometrium.

FWIW....the tiredness peaks around 7dpo...I'm like mind numbingly tired. And I get really dizzy when I stand up. And I feel out of breath. Just as an experiment last cycle I took my blood pressure when I kept getting dizzy and out of breath. 90/56. Ok...progesterone lowers blood pressure...and my progesterone naturally peaks at 6 to 7dpo....makes sense. It feels similar to early pregnancy for me....but if I'm not pregnant it will only last a day or two. If pregnant it hangs around...

I'm glad you came to a decision you can hopefully live with and succeed, @stacicali... I think upping the inositol to more therapeutic levels (4-8 grams) helps some folks. Vitex is another med. There are about a half dozen or other expensive ones that help, too... I plan to ask my endo about this when I go to see him next week. Maybe we can have some notes to compare, though since I need to stay on continuous BCP, I don't know that mine is manageable for now.

Hi there, I take progesterone pills for 10 days every month on the 20th. I am starting them today for example. I have found that they help a good deal with keeping my cycle consistent. I do have side effects which are tender breasts (they are pretty sore) and pretty intense PMS like mood swings. I have to remind myself that they just make me crazy because each month at this time I invariably freak out about something or it makes dealing with various relationships in my life harder. One thing I would say is the inositol will help. I have actually forgotten to take that recently and I remember it really helps with depression and anxiety and also cravings. But, if your doctor looks at your blood work numbers and feels you need supplements, if I were you I would take them. Natural is always better, but it doesn't always make as big of an impact. It is good to be conservative, but you can lose time if you are working against your biological clock ticking! : ) good luck to you

I've been taking 30mg daily for going on 3 weeks. But I was having constant periods... so far only breast tenderness, and sleepy so I take mine at night. This has been a God send for me