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I have lost 6 lbs in my first week. When I am all in, I tend to lose between 2-5 lbs per week, consistently.
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I have both hypothyroidism, and PCOS. I manage to lose by simply cutting my caloric intake and regular exercise.
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I'm 5'1''/5'2'', somewhere in between. My goal weight for right now is 130. I was 130 in high school, and was fairly happy with that size. I'm sure once I get there I will probably want to lose a bit more. I don't want to be under 120.