Aaron_K123 Member

That is a vaaaast overgeneralization of what the tech is capable of and although there are some example of modified adenoviral vectors being used for things like suicide gene therapy at specific cancer types I would not at all go as far as to suggest that approach is somehow generalizable to a large number of diseases.…

Yeah the number of diseases that could be addressed directly by genetic engineering would be extremely limited. Also if history tells us anything here "big pharma" will likely be the prime developer of the tech for any therapeutic use anyways. I mean current therapeutics that were developed utilizing genetic engineering…

If you had a debt of $1000 and 5 days out of the week you made daily payments of $20 but two days out of the week you made no payment would you still end up paying off your debt over time? Same answer for your caloric deficit and maintenance days.

All fair points, as I said the eye color thing just makes me "uncomfortable" not really up in arms or anything....kind of like your example of a parent giving a kid a goofy name. Partly it is just that I feel like it is a rather frivolous use of a potentially life-saving technology that could end up giving it a bad rep…

I'd consult with your doctor and not take advice of people like me on the internet. That said I do have one thought. Almost all chemotherapy drugs work by killing replicating cells in your body while leaving non-replicating cells alone. In doing so it affects the cancer (which is consistantly replicating) more than most…

So assuming it works it is a pill that encourages people to waste food. Yeah....awesome. How about instead of becoming pathological about food consumption as a society we work instead towards viewing food as fuel and a limited resource because that is what it is. I mean seriously..yeah, let's all overproduced food in…

Hi there. I wrote that post and still am around the forums. I "use" artificial sweeteners whether I'm dieting or not because i like to sweeten my drinks but dont really want to be adding a lot of calories to my day through liquids that aren't very satiating. You mentioned your studies so I'll bring up that my Ph.D is in…

It is actually completely irrelevant to my point whether the culture has a problem or not with a particular eye color or whether the child themselves ever becomes or upset with having blue eyes as a result of their parents decision. The issue is again with consent...it is still a problem that the parents made a choice that…

If you want to sell something and there is a cheaper alternative on the market then part of your marketing strategy will be to discredit the cheaper alternative. Nothing is cheaper than free and calorie counting is free....it just requires discipline. First suspicion about someone producing videos online stating calorie…

Why is string so long?

That conversion will only work for aqueous liquids given waters density is close to 1 gram per mL. It will not work for croutons at all. A crouton is going to be considerably less dense than water so your method would way overestimate how many croutons are in a serving likely by several times. If you use 1 ounce as being 2…

Calorie counting is a method for maintaining, losing or gaining weight. CICO is a rephrasing of the first law of thermodynamics (conservation of energy) where calories are the unit of energy. One is a strategy, the other is a law of nature.

Intent is the difference...and intent matters. To see that just apply the logic you used here to anything else. Bob accidentally leaves his new iPhone10 on the subway. The end result is that Bob no longer has his iPhone10 by "luck of the draw"....he didn't choose it. Joe steals Bob's new iPhone10 on the subway when Bob…

How long should you work out? How long should you make a piece of string? It depends what you are trying to accomplish...there is no way to answer the question in a general way.

blueberries, cinnamon, whole milk and aspartame or brown sugar depending.

I dont think there are any health concerns there.....but it might be considered heresy.

Also forgot that it is snowshoeing which probably makes every mile like 2 miles in terms of exercise and calorie requirements. Seems really unlikely you'll overeat in such a situation and give. it is just a 24 hour period even if you did it's not a bug deal....enjoy yourself.

Guilt is a powerful emotion and taste is subjective.

I am not strongly against it but the "designer baby" thing does make me a bit uncomfortable so I guess I'll try to explain why. For me it is about consent. If a 30 year old wants to get a tattoo that is fine by me....it is not for me but the risk is low and it's there choice. If that same 30 year old wanted to tattoo their…

I just realized you said 10 miles total not 10 miles per day. Does that mean it is 10 miles in so you hike in 10 miles then hike out 10 miles for 2 10 mile days or is it 10 miles total like 5 miles in and 5 miles out? Or are you taking multiple days to do it in. I mean if this backpack is doing like 2 miles a day or…

This. I'd focus on your gear and making sure you have a good time rather than on your diet. The exercise will take care of that for you.

you will be burning more than 2500 calories on a backpack...I'd worry more about keeping up your energy level rather than if you are eating to much. Backpacking myself I tracked and I was burning about 5000 calories per day. I was a 6' 165 pound man carrying a 20-45lb pack over 12-18 mile days over mountain terrain. Doing…

Eh....not sure how I feel about that. I like humans...I am a human....pretty much all of my friends and family are humans. I am an enviormentalist and think that our lack of action on climate change is a travesty but I care about the planet because we live on it and it is where I keep all of my stuff. It is in our best…

it I'd basically impossible to overeat while backpacking given you are carrying any food you eat for miles over difficult terrain. When I backpacked for 14 days I tried to bring the most calorie dense foods I could reasonably carry and even then I could only feasibly bring 2500 calories per day. I ended up losing almost 10…

Not sure what you mean. Are you implying that genetic engineering will destroy the Earth? If so that is a bit hyperbolic dont you think?

Exactly, I referenced CFTR earlier for the same reason...a potential clear win for the technology. My concern is that stunts like the one that started this conversation will cast the technology in a disparaging light in the public eye and cause regulatory and funding issues that will harm the development of legitimate uses…

You have no way of knowing if that is a causal effect or not but you are stating it as if they are somehow connected.

I have a conscience that nags me if I am not behaving at my best. Not sure I would call it a "ghost" or make it sound so negative or dire.

It is a nuanced issue. Genetic engineering is a tool, nothing more nothing less. Like any tool, people can use it to great effect and benefit or they can use it to harm or they can just use it ineptly. So first off I want to say I am in no way against "genetic engineering" because that would be like being against hammers.…

If you drop your overall body weight then your BMR will almost certainly be lower. You don't need a bunch of scientific studies to tell you that really, it just makes sense. That isn't a bad thing though, that is just a reality and it shouldn't make you miserable. Your BMR is going to be from three major sources: your…