I'm on Iron as well. Doc told me to take it at night, before bed. Chances are it is because of what Mumof2 said, but I never thought to ask.

Just thought of something. Have you done a saliva hormone test?
When I first started on thyroid meds, they actually made me worse instead of better. Did a saliva test and bingo! my cortisol levels were severly low (symtoms include sleep problems and exhaustion, among others). I was told that if this is occuring, the body can't handle thyroid meds properly till the cortisol problem is addressed as well. The test also shows progesterone levels, etc. If one is off kilter, it can mess up the rest.

Hashimoto's Thyroiditis patient here:

I find that keeping my vitamin levels up, (especially D3 and B vitamins) keeping my water intake around 50-64 oz on non-active days and finding hobbies that challenge me force me to think more and help fight the fog. Also, I keep my vitamins separate from my medicine by 4 hours if not more. I take my Synthroid in the morning, have breakfast 30-60 minutes later, then regular lunch. I exercise 3 times a week, with two of those days being weight lifting. I have some bouts of forgetting words or forgetfulness but not as much as I used to. Just stay calm and work it out. Make a pop-up calendar in your email and/or smartphone to keep you on track with dosing of medicine/vitamins. if I fall out of order, I readjust and keep my cool.

In the past month, I have transitioned from Low Calorie into Keto. I have lost 29 lbs in total, 15lbs of that in one month vs 3 months for the first 14lbs!

Instead of starving myself and wishing I had more to eat, I can comfortably eat anywhere from 1000-2000 calories depending on activity and hunger level. So far, so good!

I have been diagnosed as insulin resistant (hard to lose abdominal fat and just resistance to losing weight even with extreme low calories/low fat) so I also take Metformin 2x daily at 500 mcg. Now, my blood sugars stay around 80 instead of spiking all over the place from 70's to 160's. Who would of thought eating bacon/meats, eggs, vegetables, cheese and high-fat dairy to lose weight? I am proof of this and will continue to be. Screw Weight Watchers and the whole "diet" game forevermore!! All of my vitals came back on par, if not better. My TSH went from 11.6 to 2.87. I can do mental math again, I am creating more art and feeling better - aches and pains have disappeared. There must be a connection to carbs, gluten and too many processed sugars/foods that aggravate our immune systems, as any thyroid issue is an endocrine disease. I have -some- non-natural food items but I keep them limited. If keto works for my severe metabolic issues, I may have discovered a breakthrough for those who cannot lose weight through conventional "eat less, exercise more" regime who are also afflicted with Hashimoto's/Hypothyroidism.

For those who are interested, I found an interesting article that may be of some help to any of you. I know it did for me. I talked with my Endocrinologist and we discussed about adding in Metformin to assist with keeping blood sugars level to help lose weight after multiple failed attempts.

http://www.stopthethyroidmadness.com/2012/05/30/hypothyroidism-insulin-resistance-and-metformin/

Good Luck to all of you. I would enjoy hearing what you think.

A lot of your symptoms could also be low iron, I never felt better on iron til my numbers were above 70. ( I had to do injections- pills were not doing it)

@Syriene
Hm, I will ask about it next time I go to see my endo - but to be honest, all I can do is ask and hope that she will OK it. Here in Germany the doctors are extremely reluctant to do any tests at all. I had to fight for a T3 / T4 test at my GP's office and so far they have ignored any suggestions to do a gluten test ( I have had some bad stomach trouble for a couple of weeks now, but they may be due to stress ).
What can you do when you get tested and they find out that your cortisol levels are not OK?

I was put on a low dose of cortisone (nothing near the amount they may give for sinus infections, etc). As of right now I'm on 5mg once daily, but will have to boost it up to twice daily soon. So far, I have noticed a difference. Hoping by upping the dose, it will be even better. I don't know if the Rx will be a life long thing or not though- will find that out next visit.
Sorry to hear you have so much trouble with testing. I had to pay for the saliva test out of pocket (no insurance companies cover it here), but I have heard that there is also a blood test. I'm not sure of an official test name, but maybe you would have better luck with that one. I have a friend in Hungary that wants to do the saliva test, but there, everything is separate. You have one test for the adrenals (cortisol) and then another for anything ovarian related. She's having to do them spread out so the cost won't be so bad. Here, both are done at the same time, with one cost.

as for the stomach issues- one of my coworkers was having probs and thought it was gluten- come to find out- too much calcium! With all the different sources out there, it's hard to know what the right supplement amount is.

I hope you find a solution and feel better soon!

A lot of your symptoms could also be low iron, I never felt better on iron til my numbers were above 70. ( I had to do injections- pills were not doing it)

I also had to do the injections, and those seemed to work. However, I got a nasty stain on my arm from one of them...has this happened to anyone else?