I usually take mine in the morning, at least a half an hour before I eat. Take this medicine on an empty stomach. Take it with a full glass of water at least 30 minutes to 1 hour before eating breakfast. Also, it should be taken at least 4 hours before or 4 hours after antacids, calcium, or iron supplements. At least that is what is says on my label.

There will always be someone who finds this "works" and you may even be one of them. The question is "does it work properly?" If you hinder absorption that just means it's not going to be working to the fullest extent possible and you may have erratic results. For me, it's my forever drug. I don't have a thyroid any more, so I need the levo to work. And for me, that means taking it as soon as I wake up and doing every other possible part of the morning routine before eating. Shower, clothing, makeup, lunch preparation, all that usually takes about 45 minutes, which so far, has been enough time.

I also imagine it may depend on what you need the levo for. I've read here in the forums that there are several other brands of med that could do the same thing. Maybe one of them has instructions that fit your lifestyle better.

Good luck!

I never take mine at the same time every day - it all depends when I get up. I try to take it at least 30 minutes before eating (sometimes I've also taken it a night) but sometimes I eat breakfast straight away if I'm REALLY hungry. When I take it never seems to have affected my blood test results.

I think the most important thing is to make sure you DO take it every day. I can really feel if I miss it for a few days (I'm forgetful when I pack away bags sometimes...and with renewing prescriptions!).

What do y'all think about black coffee?

I try to take mine the second I wake up and then wait a good 20-40 minutes before I eat anything. I cook my kids food right away, though, and really more often than I care to admit, I sneak a bite before my 30 minutes is up. My levels are fine. Maybe they would be better if I was better at it.

Personally, my schedule is just insane. I consider it a job well done if I manage to take it every day at all. I keep old bottles at lower doses around to stash in various places so that if I have forgotten or wasn't at home in the morning I can take one and a half. I'm sure my endo would love that!

As everyone's grandpa probably said: don't let the perfect be the enemy of the good.

I found taking mine on an empty stomach or a full stomach never made a difference in my levels. Not when I was on Synthroid and not now on WP Thyroid. What does work tho is consistency. I wake up at the same time every day and that is when I take my pills. I'm usually eating 10 minutes after that and drinking coffee 20 minutes later. If you're taking at the same time as breakfast, then just make sure you do that everyday.

Recent studies have suggested that it might even be best to take thyroid meds at nite.

http://thyroid.about.com/od/thyroiddrugstreatments/a/bedtime.htm

I have been taking mine at my middle of the night (3-4a), but this morning I woke up and my pill was still there on the nightstand! ???? So I took it with my coffee. I don't think one day will be detrimental, but I might start taking it before I go to bed if this happens again! I have to have my coffee before I do anything in the morning!

My doctor put me on Tirosint a couple years ago because I had this problem, it is a little gel type pearl that absorbs a lot quicker so you do not need to wait as long before eating etc. It really worked for me but it was pretty darn expensive and I was an unemployeed college student at the time so after using the free box she gave me and then using the coupon for my first prescription of it I had to go back on Synthroid (which can also be expensive). I think I may ask her at my next appointment for it again as I am now a full time employeed graduate. Might want to look into it....

I take mine upon waking somewhere between 5am-7am. By the time I watch a little tv or get ready for work the hour has passed. Always on empty stomach with a glass of water.

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On 175/200mcg alt day and take it first thing in the morning around 0500. Drink 16 oz of water around 0600 and another on my morning commute. Have a protein bar around 0800. On weekends I do the same, but eat a little earlier and try to fit in cardio before 0800.