I know this is an old post, but has anyone tried Pregnitude? It has 2000mg of myo-inositol, as well as 200mcg of folic acid. Thinking of ordering (only available online through the pregnitude website, amazon and the walgreens site, for about $40 for a 1 month supply).

That's pretty expensive for a one month supply of two vitamins IMO. You can buy the myo-inositol off Amazon for $55 for a huge tub that lasts me almost 3 months and you can buy folic acid for dirt cheap at any drug store/walmart, etc.

I thought the same thing! I'm super cheap, and I was trying to research if taking just folic acid supplelent + a myo-inositol supplement would be the same thing (since this apparently all that Pregnitude has) and some of what I read was that you would have to take large amounts of the myo to get the equivalent of the amount in that product (2000mg) and that in the long run, you end up spending the same, or more. I'll have to do some more research before ordering. Thanks for the advice!

Hello all. I was researching d-chiro way back in 2008 & then life intervened & I forgot all about it — but I remembered it just yesterday & have been updating my research. So, I have some possible good news for those of you investigating this track who have been worried about its cost.

Per http://examine.com/supplements/Inositol/#summary7-0 —

"Other studies have noted improvements in androgen and glucose metabolism (the main concerns with PCOS from a health perspective[138]) that exceed placebo with 12 weeks usage of 1,200mg myo-inositol,[135] 8-12 weeks usage of 2,000mg myo-inositol,[134][146] up to three months supplementation of 4,000mg myo-inositol,[147] and combined therapy with myo-inositol (550mg) and D-chiro-inositol (13.8mg) over 12 weeks.[3] "

(Those numbers in brackets refer to scientific studies.)

Read the rest of that section as well, as it says more about COMBINED THERAPY for various issues that come up with PCOS (such as fertility) using both myo & d-chiro-insoitol, generally in about a 40:1 ratio (myo to d-chiro) — and in this combined therapy, the dosage for BOTH is far lower then when either is used on its own. Basically, they have a synergistic effect. I spent some time on Pubmed today locating studies, including some quite recent, and some of these appear to confirm the 40:1 synergistic ration between myo & d-chiro. I'll be glad to share the citations & abstracts if you're interested.

In practical terms, best I can tell nobody is making a supplement with this ratio, so at this point one is stuck buying both products & figuring out how to mix them at that ratio. Well, that's what I'm going to do. I just ordered two bottles of Chiral Balance's DCI (600 mgs d-chiro-inositol, 60 pills per bottle). Those pills appear to be pure d-chiro-inositol in a vegetarian capsule, which means they can be opened up & the powder spilled out. I will simply start by measuring out around 14 grams on my counter scale & mixing it with the 550 mg of myo-inositol. Thus, one 600 mg pill from Chiral Balance will supply 42 doses of the d-chiro-inositol needed for this combined therapy.

Edit: Brain flatulence! My scale measures grams, but not milligrams, so I'll either have to find a finer measuring system, or just satisfy myself with larger than ratio dosages of the d-chiro. Not sure that it has to be at such an exacting ratio in the first place....

— Mel in Anchorage, AK

bump!

bump

I see that this thread is pretty old but I wanted to share my success story with myoinositol! We had been ttc for 2 years and I was at my witts end with everything, I had only gotten two periods the whole time and was very frustrated. I found out about myoinositol and decided to try it. In just 3 months it had given me two periods and my BFP! We then found out that we were pregnant with twins! Unfortunately we just lost them at 12 weeks (chromosomal issues, nothing to do with the pcos) I am devistated but SO hopeful that I will have another bfp soon thanks to this amazing supplement! Never give up hope ladies!

@littleklee thank you for sharing your story. I'm so sorry for the loss of your babies. Glad the myoinositol seemed to help you though; hope you get a sticky rainbow baby soon!

I took your advice and bought a container of inositol. I just started it 2 days ago so this may be coincidence but I just got my period! (if I don't take hormones my body normally doesn't produce a period so this is really exciting news). I'm looking forward to seeing how else my body reacts to inositol, but so far it's looking really good.

I have a tub of myoinositol but have not taken it regularly. I think I took it consistently for two weeks, and then stopped. I did not feel any different on vs off.
I have been on metformin for about 6 months and if anything, my libido is kaput.
Nada.
Zip.
Zero.
Zilch.
Nonexistent.
I'm stopping the metformin and will start taking myoinositol tomorrow and see what happens...