When you say 'gym machine equipment' do you mean the strength training equipment and not cardio equipment (like a treadmill)? I'm going to assume yes.

The most important thing is to stick with it! It may take a while before you start to see results. If you are a member at a gym, they likely offer an introductory overview on the equipment. Take advantage of that!

Make sure you hit all of your major body parts (bicep, tricep, shoulder, chest, back, legs, core). Without making it too complicated, also remember that each "body part" consists of multiple muscles so you want to have variety. For example, a bicep curl where your palm faces the ceiling works your bicep muscle differently than when you curl with your palms facing each other.

Rest at least one day between strength training workouts. For me, I do my strength training on Tuesday, Thursday and Saturday and I do my cardio on the 'off days' (e.g. Monday, Wednesday, and Friday). I either rest on Sundays or do something light (e.g. walking).

Again, stick with it! When I first started, my strength training days were not something I looked forward to -- on any day. Now, I look forward to them and I even get a little sad if I have to miss a day!

Bodybuilding.com has alot if information