Yet Another VAP (cholesterol inside!)
wabmester
Posts: 2,748 Member
VAP = Vertical Auto Profile. It gives you more insight into your lipid profile than the standard test. I just got my 3rd results, and the 2nd on low carb.
(For biochem geeks, they use gel electrophoresis to do the test.)
My first results were in 2009, 5 years before low carb. Not pretty.
HDL=37, TG=302, LDL=115, TC=224, LDL was pattern B -- small, dense.
3/2015, about 3 months after going low carb:
HDL=40, TG=134, LDL=140, TC=212, LDL switch to pattern A -- large, fluffy.
That was a huge improvement, but still borderline in terms of risk markers.
10/2015, about 10 months of low carb.
HDL=57, TG=80, LDL=153, TC=230, pattern A.
Those are SOLID results. My HDL is almost in the HIGH range for males now. The increase in LDL is somewhat concerning, but let's look at the breakdown.
They break LDL into 6 constituent particles: 4 types of LDL, IDL, and Lp(a). I want to look at trends of the LDL constituents while low carb, so I have 2 data points:
LDL1 went from 20.9 to 23.8, an increase in large, fluffy
LDL2 went from 27.2 to 48.7, an increase in large, fluffy
LDL3 went from 55.9 to 49.6, a decrease in small, dense
LDL4 went from 8.0 to 0.7, a decrease in small, dense
IDL went from 22 to 21, a decrease in atherogenicity
Lp(a) went from 6 to 9, an increase in atherogenicity
So in terms of LDL, 5 out of 6 markers improved.
They also measure Apo B/A1, a lower ratio means lower risk, and mine went from 0.83 to 0.72.
In all total, the report gives 19 different risk markers.
Going from 3 to 10 months of low carb, 12 out of 19 risk markers improved, 7 got worse.
Most of the 7 that got worse reflected higher LDL concentration.
In a separate test, I had my CRP (inflammation marker) measured, and it's low (0.1).
So my only concern at this point is LDL. It is a well established risk factor, IMO. While this test didn't measure particle COUNT, the indications from the large fluffy pattern and apo B levels suggest that my LDL count is pretty stable.
One of the factors affecting LDL is MUFA vs SFA in the diet, and my MUFA content is already pretty high due to nuts.
(For biochem geeks, they use gel electrophoresis to do the test.)
My first results were in 2009, 5 years before low carb. Not pretty.
HDL=37, TG=302, LDL=115, TC=224, LDL was pattern B -- small, dense.
3/2015, about 3 months after going low carb:
HDL=40, TG=134, LDL=140, TC=212, LDL switch to pattern A -- large, fluffy.
That was a huge improvement, but still borderline in terms of risk markers.
10/2015, about 10 months of low carb.
HDL=57, TG=80, LDL=153, TC=230, pattern A.
Those are SOLID results. My HDL is almost in the HIGH range for males now. The increase in LDL is somewhat concerning, but let's look at the breakdown.
They break LDL into 6 constituent particles: 4 types of LDL, IDL, and Lp(a). I want to look at trends of the LDL constituents while low carb, so I have 2 data points:
LDL1 went from 20.9 to 23.8, an increase in large, fluffy
LDL2 went from 27.2 to 48.7, an increase in large, fluffy
LDL3 went from 55.9 to 49.6, a decrease in small, dense
LDL4 went from 8.0 to 0.7, a decrease in small, dense
IDL went from 22 to 21, a decrease in atherogenicity
Lp(a) went from 6 to 9, an increase in atherogenicity
So in terms of LDL, 5 out of 6 markers improved.
They also measure Apo B/A1, a lower ratio means lower risk, and mine went from 0.83 to 0.72.
In all total, the report gives 19 different risk markers.
Going from 3 to 10 months of low carb, 12 out of 19 risk markers improved, 7 got worse.
Most of the 7 that got worse reflected higher LDL concentration.
In a separate test, I had my CRP (inflammation marker) measured, and it's low (0.1).
So my only concern at this point is LDL. It is a well established risk factor, IMO. While this test didn't measure particle COUNT, the indications from the large fluffy pattern and apo B levels suggest that my LDL count is pretty stable.
One of the factors affecting LDL is MUFA vs SFA in the diet, and my MUFA content is already pretty high due to nuts.
0
Replies
-
That a great improvement. I wouldn't sweat the LDL if the rest is going in the right direction. Mine changed drastically as well. My LDL did go up, but because my HDL is SO high (125) my ratio is crazy low.0
-
Wonderful, and detailed - thanks for sharing. Very helpful.0
-
Way to go and yes thanks for sharing the in-depth details!0
-
Wow. Thanks! That is quite the change... You make me want to get tested now.0
-
That is an awesome test. I am stuck with the basic profile so I have to do a lot of assuming abut particle size.
The free lipid screen last week showed my way of eat is helping just comparing my 10 Aug 2015 (was on the WOE 10 months at that time) and 13 Nov 2015 results. I had just lost 15 pounds at the 10 Aug testing. I had gained back 5 pounds just after the Aug testing because of the bad numbers since I am trying to renew some life insurance.
10 Aug 2015 / 13 Nov 2015
404 / 310 Total Cholesterol
324 / 228 LDL
56 / 72 HDL
121 / 52 Triglycerides
We will see if this formatting will hold. It did so after adding the /.
onlinelibrary.wiley.com/doi/10.1113/expphysiol.2006.035147/full
While this article is Pro Med just skip down to Cholesterol metabolism for fine details on cholesterol.
0
This discussion has been closed.