Help! Doc just ordered glipizide
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JessicaLCHF wrote: »The med she's talking about is Byetta, twice a day. I'm going to price it out and see if it's doable. She mentioned two others in today's email that I can also look into: Januvia and Trajenta. I'm going to research them all a bit.
Byetta, Januvia, Trajenta - I'm starting a new thread on these.
There's also an injectable called Saxenda. I just started it yesterday. I'm not diabetic, but I have PCOS and go through reactive hypoglycemia, and my endo just put me on it in hopes that some weight loss and a switch in my metformin/spiro/BC combo will jump start a period.
It's not covered by my insurance, but there's a copay card in the box that is $200 a month if you're paying out of pocket.
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KnitOrMiss wrote: »For pain, @GaleHawkins has been using some great protocols!
Personally, I've been experimenting with turmeric and ashwagandha...and boron/zinc. Seems to be making some improvements, though it's hard to tell yet.
https://ketolivewell.com/supplements/
Actually the protocols I have found came from my efforts to prevent/recover from cancer that could have been secondary to starting Enbrel injections back in Aug 2014. By cutting out sugar and all forms of all grains my pain levels dropped like a rock so I never started the Enbrel injections. Because of cancer deaths in my family I have stayed full bore on studying supplements that along with LCHF that can help prevent and or reverse different types of cancer.
Many of the supplements in my list make claims of being useful to prevent and or reverse diabetes, cancer, etc. It seems like many plant based supplements that can lower CRP levels and be helpful in pain manage as well as disease management.
Personally never having been diagnosed with anything other than arthritis I can not speak to the validity of any claims coming from the research of others be it animal or human trials but some of the research I find very interesting to read.
My take is about 95% of all disease in the human body comes after years of low grade inflammation that over time weaks the immune system so it can no longer completely fend off cancer, etc. Fixing leaking gut and blood brain barriers I expect is job one to prevent many autoimmune and neurological disease states.
Pain is a signal that there is inflammation that will in time lead to our premature death as I see it today. Masking pain vs. resolving the inflammation causing the pain I think is leading to disease states more and more. Fat cells produce inflammation daily we read.
Least Common Denominator in most all diseased states seems to be inflammation inside our bodies. Often this can be subclinical and is the reason we learn too late to act to prevent premature death.1 -
JessicaLCHF wrote: »I'm sure my chronic pain isn't helping either and the resultant poor sleep. On top of that I've been getting lockjaw every few days due I believe to teeth clenching in my sleep. I think I have the pillow trick for preventing it figured out. Hopefully.
After a long winter I'm sitting here in a 93 degree day in Vermont (nice!) with a heating pad on my knot in my shoulder for relief (not so nice). But maybe I'll lose some weight! It's like a sauna! Lol.
re: teeth clenching.... my thing totally. I cannot sleep with a pillow or I roll onto my side and shove my jaw sideways into the pillow
so I sleep on my back without one. My dentist and my orthodontist both are surprised by the amount of damage to both my teeth and my jaw joints & muscles... I have a new 'splint' I'm trying at night (2 nights so far) that seems to help. It's a Nociceptive Trigeminal Inhibition Tension Suppression System - big name, small device:
studies show it reduces the masseter temporalis muscle contraction force by between 75 & 80%. I also have a full upper splint to protect the edges of my teeth but tend to clench hard all night on it. Likely I will have to alternate, but we'll see in another couple weeks.
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Yikes. I'm trying to avoid having to go there. It's been about three months. I hate it. If it's not one thing...0
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I don't want to derail this and ask a question about the teeth grinding, but I will anyway. I have always wondered why people don't just use the mouth guards you wear when playing hockey/whatever. They can be custom molded and trimmed for a good fit.0
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I don't want to derail this and ask a question about the teeth grinding, but I will anyway. I have always wondered why people don't just use the mouth guards you wear when playing hockey/whatever. They can be custom molded and trimmed for a good fit.
That will be my first attempt but can you imagine the drooling and uncomfortableness of having that in your mouth all night? Not looking forward to it. I'm hoping it just stops on its own. If I get my head and neck in a certain position with my pillow it seems to help. Theres actually a YouTube on this. This woman explaining her dog face pose. Lol. Yes, I've been researching a bit.0 -
cstehansen wrote: »In regard to berberine, there are several studies. This is one where you can get to the full text and shows pretty solid data that it is effective for BG control. However, like every study, it shows it is not 100% of people that gain benefit. The same can be said of metformin, though.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377488/
Have you run across any detailed summaries of berberine interactions? I've seen some references to "possible" interference with diabetes and hypertension meds, but nothing remotely useful. Thx!1 -
JessicaLCHF wrote: »
That will be my first attempt but can you imagine the drooling and uncomfortableness of having that in your mouth all night? Not looking forward to it. I'm hoping it just stops on its own. If I get my head and neck in a certain position with my pillow it seems to help. Theres actually a YouTube on this. This woman explaining her dog face pose. Lol. Yes, I've been researching a bit.
Dunno - I don't remember a trail of slobber when I was playing football or lacrosse. People get used to sleeping with things like a CPAP. I am sure it is not ideal.
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I've worn a "bite plate" for 30 years when I sleep. Mine was made specifically for me but I've never drooled that I'm aware of during my sleep and it was easy to get adjust to. Well, If I drooled it was dry before I woke up in the AM.1
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cstehansen wrote: »In regard to berberine, there are several studies. This is one where you can get to the full text and shows pretty solid data that it is effective for BG control. However, like every study, it shows it is not 100% of people that gain benefit. The same can be said of metformin, though.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377488/
Have you run across any detailed summaries of berberine interactions? I've seen some references to "possible" interference with diabetes and hypertension meds, but nothing remotely useful. Thx!
Berberine will interfere with Metformin but you should have no need for Metformin since based on what I have read at examine.com on berberine. Berberine at first seemed to make me go low the first day or two. It is stated to regulate BG down to normal but drive it below normal but one needs to be very aware its impact in each case.
I take 500 MG 3x daily of berberine at this time along with three or four other similar acting plant extracts. A month in I got new lab work last week. Fast BG has ran from 102-108 over the last four years. Last week it was 88 and A1C had dropped from 5.2 to 5.1 but that is within margin of error. I was very happy to finally come in under 100 on an official lab report.2 -
I don't want to derail this and ask a question about the teeth grinding, but I will anyway. I have always wondered why people don't just use the mouth guards you wear when playing hockey/whatever. They can be custom molded and trimmed for a good fit.
A mouth guard protects the teeth from harmful impact but does not work on bruxism. Those ones you can buy at the pharmacy/drugstore and heat up in hot water to shape are especially useless. A mouth splint holds the teeth and jaw in the correct position and must be custom fitted to move the jaw into a neutral position. I tried the store bought ones first of course because I was unwilling to pay the close to 3000 dollars for the custom made splint from the orthodontist as there was a good chance in my case that it wouldn't work anyway. The cost included all orthodontist appointments for the 6 months build and follow up and any extra appointments I requested in case of problems.
No drooling happens when your splint fits properly.
You can google the difference from livestrong.com/article/475895-mouth-splint-vs-mouth-guard/0 -
Hi, I'm a doctor from Australia. I've read some of the suggestions from member and think some could be potentially dangerous with a gliclazide (e.g. Fasting). Your doctor likely is concerned regarding insulin resistance given your carbs are relatively low and you continue to have high blood sugar readings. I think you should discuss your concerns with your doctor. Best of luck!1
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canadjineh wrote: »A mouth guard protects the teeth from harmful impact but does not work on bruxism. Those ones you can buy at the pharmacy/drugstore and heat up in hot water to shape are especially useless. A mouth splint holds the teeth and jaw in the correct position and must be custom fitted to move the jaw into a neutral position. I tried the store bought ones first of course because I was unwilling to pay the close to 3000 dollars for the custom made splint from the orthodontist as there was a good chance in my case that it wouldn't work anyway. The cost included all orthodontist appointments for the 6 months build and follow up and any extra appointments I requested in case of problems.
No drooling happens when your splint fits properly.
You can google the difference from livestrong.com/article/475895-mouth-splint-vs-mouth-guard/
I wondered and now I know...
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canadjineh wrote: »I don't want to derail this and ask a question about the teeth grinding, but I will anyway. I have always wondered why people don't just use the mouth guards you wear when playing hockey/whatever. They can be custom molded and trimmed for a good fit.
A mouth guard protects the teeth from harmful impact but does not work on bruxism. Those ones you can buy at the pharmacy/drugstore and heat up in hot water to shape are especially useless. A mouth splint holds the teeth and jaw in the correct position and must be custom fitted to move the jaw into a neutral position. I tried the store bought ones first of course because I was unwilling to pay the close to 3000 dollars for the custom made splint from the orthodontist as there was a good chance in my case that it wouldn't work anyway. The cost included all orthodontist appointments for the 6 months build and follow up and any extra appointments I requested in case of problems.
No drooling happens when your splint fits properly.
You can google the difference from livestrong.com/article/475895-mouth-splint-vs-mouth-guard/
Yeah I wondered about that. Cause the issue is the muscles clamping down, right? So instead of on teeth you'd just be clamping on the guard but it's still overworking the jaw all night.0 -
chantelleferreira992 wrote: »Hi, I'm a doctor from Australia. I've read some of the suggestions from member and think some could be potentially dangerous with a gliclazide (e.g. Fasting). Your doctor likely is concerned regarding insulin resistance given your carbs are relatively low and you continue to have high blood sugar readings. I think you should discuss your concerns with your doctor. Best of luck!
When I first started LCHF 2 years ago, Glipizide was the first drug my Endo stopped.
We're still trying to get my diabetes dialed in, but Glipizide hasn't been added back in.
So far diet has the most effect, followed by meds then exercise.
Years ago meds could do the whole job but now it's a different story.
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