Anyone else looking at Nutrigenomics?

toadqueen

I only recently read about using DNA/gene analysis to look at food and supplements. It is very fascinating. I had my DNA tested for genealogy for fun earlier in the year. I have used the data in a few analysis tools such as Nutrahacker, KnowYourGenetics, and PrometheaseOnDemand recently. According to Nutrahacker I should be eating a ketogenic diet and have issues with B12, a propensity for metabolic syndrome and food sensitivities. This was substantiated with the last tool. POD also made me glad I'm female because I am at high risk for prostate cancer according to my gene mutations. KnowYourGenetics listed a bunch of supplements I should be taking but I am taking a lot already and it is very involved reading so I will delve into that more at a later date.

wabmester

No, but I was just reading about it. The consensus seems to be that it's promising, but not ready for prime time. Still too many unknowns. Even for diabetes, they can only explain about 10% via genetic info. It's much less accurate for "carb intolerance" -- high triglycerides and high insulin seem to be the best indicators.

m_puppy

I've never heard of it but it sounds interesting. What does it all entail?

toadqueen

There are companies and medical professionals that analyse your DNA gene mutations for susceptability to diseases and make recommendations for food and supplements for one's best health based on their findings. This is a very simplistic answer, but that is my current level of understanding.

I found that my gene analysis corresponded to prior food and allergy testing I had done previously through blood tests. It took me years to confirm that I should be eating a ketogenic diet and my genes pointed to it directly. Most of the delay were doctors and nutritionists and everyone else telling me it was not healthy.

I already had the DNA data. It costs about $99 from most companies I looked at.

sweetteadrinker2

I've heard a lot about this recently, along with the testing for a mutation that puts you at high risk for cancer being used for couples to have a healthy baby. I really like the idea, and hope that by the time I'm ready for kids it'll be ready for widespread use. The diet one I'm not too sure of at this point, I think it can provide a good base for what kind of diet you should be eating but it needs to take into account where you live, age, sex, goals, etc before I'd really trust it enough to make decisions based on it.

minties82

I had never heard of this before. It sounds amazing! I found a place that does it in New Zealand but it's expensive here ($550 plus a tax of 15%). I would love to pay for my grandma to have it done, she has rheumatoid arthritis and I am so sure that dietary changes could help her with the pain.

KnitOrMiss

My PCP told me that they are going to implement this sometime this calendar year at their facilities, and she's looking forward to giving me the testing to help see if we can get to the root of some of my more problematic issues. Interesting to hear some good feedback on it.

@toadqueen Just from my bloodwork and recent labs alone, it sounds like you and I have a lot of medical concerns in common! LOL

Twibbly

wabmester wrote: »

Even for diabetes, they can only explain about 10% via genetic info. It's much less accurate for "carb intolerance" -- high triglycerides and high insulin seem to be the best indicators.

Dr. Perlmutter said that over 90% of the DNA in your body is from bacteria. In the same interview (Jimmy Moore's podcast), he talked about a doctor who reversed type 2 diabetes with a fecal implant. To my ears, that sounds like diabetes may be at least partially caused by the blend of bacteria in the gut. The answers to everything might not be in our DNA.

Twibbly

Oh, and maybe I've watched Gattaca too many times, but I won't get DNA testing done in the states until there are more protections on how the information can be used.

jennybird99

Michael Mosley's show, the Truth about Exercise, or one of the other ones ( no more short-term memory here, folks), showed genetic testing for whether or not one is resistant to metabolic improvements through exercise, easily adaptable to those changes, or muffle-of-the-road. Also used the HIIT, the bikes you cycle on at 100% of your capability for 20 seconds times 3, 3 times a week. I actually mailed off a sample, about $175.00....have me some recommendations, and I'm the middle of the road responder to V02max improvement with exercise. Let me find it.
But this all sounds very interesting.
So does/do fecal transplant for diabetes. Type II I assume. I've heard of it for c. Diff, but never for this. But if gut bacteria shortage/inefficiency contributes to inflammation, therefore malabsorption, etc., then this makes sense. Gross, intimate sense.