Vegetable fat not the route to a healthy heart

FIT_Goat
FIT_Goat Posts: 4,224 Member
edited April 2016 in Social Groups
This came across my feed today. I feel like most of the members here know this already, but just in case.

http://www.livemint.com/Politics/9uD6kaYZGowdBuooWPlfwN/Vegetable-fat-not-the-route-to-a-healthy-heart.html
Switching from saturated to unsaturated Omega-6 fats did result in lower blood cholesterol in a trial with nearly 10,000 participants, it said, but not the expected reduction in heart disease deaths.

In fact, those with a greater reduction in cholesterol “had a higher rather than a lower risk of death,” according to the research published by the medical journal BMJ.

Edit: Link to actual study: http://www.bmj.com/content/353/bmj.i1246

Replies

  • wabmester
    wabmester Posts: 2,748 Member
    They're talking about a 1961 study. Guess who did the study. Ancel Keys. :)
  • FIT_Goat
    FIT_Goat Posts: 4,224 Member
    edited April 2016
    Call me paranoid, but this is a look at data from 1968-1973.
    The Minnesota Coronary Experiment (MCE), a randomized controlled trial conducted in 1968-73, was the largest (n=9570) and perhaps the most rigorously executed dietary trial of cholesterol lowering by replacement of saturated fat with vegetable oil rich in linoleic acid. The MCE is the only such randomized controlled trial to complete postmortem assessment of coronary, aortic, and cerebrovascular atherosclerosis grade and infarct status and the only one to test the clinical effects of increasing linoleic acid in large prespecified subgroups of women and older adults.

    Despite the potential importance of this trial, critical analyses prespecified by the original MCE investigators have not been previously published or considered part of the evidence base

    Could it be that the study gave the opposite results from what was desired the reason that we are only seeing this data now? I mean, this was ignored or covered up for almost 50 years! Someone better fetch me my tinfoil hat!
  • wabmester
    wabmester Posts: 2,748 Member
    Because the trans fatty acid contents of MCE study diets are not available, one could speculate that the lack of benefit in the intervention group was because of increased consumption of trans fat. Indeed, in addition to liquid corn oil the intervention diet also contained a serum cholesterol lowering soft corn oil polyunsaturated margarine, which likely contained some trans fat.

    This will taint their results for sure. Interesting from a historical perspective, but missing key data.
  • KnitOrMiss
    KnitOrMiss Posts: 10,103 Member
    Also, aren't veggie oils the ones with way more Omega 6's that 3's? And the low 3's to 6's ratio is a HUGE thing, right? I can't remember the references, but I remember the convo...
  • wabmester
    wabmester Posts: 2,748 Member
    Yeah, they fed them corn oil and margarine. Omega-6 and trans-fats.

    The ratio thing is sort of speculative, but a lot of people think it's a clue.

    https://proteinpower.com/drmike/2016/02/03/will-the-new-dietary-guidelines-fatten-us-even-more/
  • Sunny_Bunny_
    Sunny_Bunny_ Posts: 7,140 Member
    FIT_Goat wrote: »
    Call me paranoid, but this is a look at data from 1968-1973.
    The Minnesota Coronary Experiment (MCE), a randomized controlled trial conducted in 1968-73, was the largest (n=9570) and perhaps the most rigorously executed dietary trial of cholesterol lowering by replacement of saturated fat with vegetable oil rich in linoleic acid. The MCE is the only such randomized controlled trial to complete postmortem assessment of coronary, aortic, and cerebrovascular atherosclerosis grade and infarct status and the only one to test the clinical effects of increasing linoleic acid in large prespecified subgroups of women and older adults.

    Despite the potential importance of this trial, critical analyses prespecified by the original MCE investigators have not been previously published or considered part of the evidence base

    Could it be that the study gave the opposite results from what was desired the reason that we are only seeing this data now? I mean, this was ignored or covered up for almost 50 years! Someone better fetch me my tinfoil hat!

    I gotchu
    gyru1pusrhpu.jpeg
  • kmn118
    kmn118 Posts: 313 Member
    lol on the pic!!! I was at the market yesterday and saw someone put a large tub of the store brand margarine in their cart... it was all i could do to keep my lips zipped and my hands out of his cart to cast it away!
  • KarlaYP
    KarlaYP Posts: 4,436 Member
    There was an article in the Washington post on this topic yesterday too! Hey @Fit_Goat, I've been wearing an aluminum foil hat for a long time already!! Lol! Thanks for the pic @Sunny_Bunny_!

    In the post article (it wouldn't allow me to link the article) it said that the U.S. is phasing out the use of vegetable oils over the next three years! Did mention the skewed data from Ancel Keyes too, but went on to say they couldn't understand how the fat heart hypothesis was credited as a thing!
  • KarlaYP
    KarlaYP Posts: 4,436 Member
    Thank you @LINIA !!
  • Dragonwolf
    Dragonwolf Posts: 5,600 Member
    kmn118 wrote: »
    lol on the pic!!! I was at the market yesterday and saw someone put a large tub of the store brand margarine in their cart... it was all i could do to keep my lips zipped and my hands out of his cart to cast it away!

    Oh man, I have a gig doing grocery delivery (people build a list in a third party app, I go to the store and buy the stuff and deliver, they pay through the app, the company the runs the app puts funds on a card to pay for the groceries), and I cringe every time margarine is on the list.