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As of this morning, no longer overweight!

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  • LowCarbInScotland
    LowCarbInScotland Posts: 1,027 Member
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    Congratulations on such a positive health indicator! Sounds like you achieved this success at a good time, when your body needed it the most. I wish you all the best with your recovery.
  • Foamroller
    Foamroller Posts: 1,041 Member
    edited May 2016
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    From my very layman understanding:

    - High bloodsugar is toxic to cells. Both endogenous and exogenous glycation of amino acids (protein) and lipids (fat) disrupt cell function over time. AGEs wreck havoc. https://en.m.wikipedia.org/wiki/Advanced_glycation_end-product

    - Many diseases are correlated such as DM and breast cancer. DM and Alzheimer's. I'm guessing the glycation is at the root of many diseases.

    - Ketosis, fasting and exercise help the body with better glucose disposal and hormonal balance. Intermittent Fasting reduce liver glycogen faster than if eating 3x/day. Exercise can increase muscle fiber and thereby function as a bigger glucose sink. After age 40 the rate of sarcopenia increases even more just by being sedentary. It might explain why age is a HUGE factor in many cases of DM,cancer and Alzheimer's.
    - Research the Warburg effect hypothesis for cancer (see Thomas Seyfried).

    https://youtu.be/SEE-oU8_NSU
    https://youtu.be/fXWE8vQB0eA

    ...there's also the anecdotal story of cancer survivor Andrew Scarborough.

    - Fasting and exercise increases the autophagy process, the body's self repair and healing by getting rid of cellular junk. because they both lead to energy depleted state.
    - mTOR is a crucial signalling pathway for autophagy, protein synthesis and a whole bunch of other stuff.
    - mTOR is ONLY inhibited at energy depletion and especially low levels of leucine.

    Overview:
    http://jcs.biologists.org/content/122/20/3589

    I also recommend to read David Perlmutter's book "Grain Brain". A lot of pieces fell into place for me, especially about "protein misfolding". Which could be just another word for cancer.

    TL;DR A lifestyle that increases autophagy, recycling cellular debris is anti-ageing.

    There are unfortunately no guarantees in life. But this is more promising than many of the outright hoaxy schemes out there for desperate patients. My cousin operated a biodegradable chemotherapy capsule into his brain. It bought him 1 year or so. But in the end he refused to do scorpion poison, which at the time was an alternative treatment. He was 43 yo.

    My father died of colon cancer and my mum has had cervical twice. So, yeah I have a personal interest.

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