Is Your Glucose Metabolism Unique to You?

RalfLott

Interesting ideas in this episode (and lots more at thequantifiedbody.net)

https://thequantifiedbody.net/glucose-metabolism-eran-segal-lihi-segal/

What You’ll Learn

• Studying the glucose response as a quantifiable effect food has on our bodies (05:43).
• Post-meal glucose levels represent direct tracking of response to different foods (13:00).
• Tracking glucose spikes and quantifying the body’s post-meal blood glucose regulation (14:17).
• The accuracy and usefulness of continuous glucose monitoring – new devices and helping research (14:55).
• Constructing multifactorial algorithms for personalized prediction of blood glucose response (18:53).
• Using high-resolution microbiome sequencing to detect specific strains of microbiome bacteria (20:31).
• Compared to BMI or blood tests, the microbiome is a more significant factor in predicting glucose metabolism in a personalized way (22:55).
• Different microbiome features contribute to the overall prediction of response (22:56).
• The propensity to gain weight and the effects of artificial sweeteners (26:11).
• The microbiome’s acquired ‘memory’ regulates weight gain mechanisms (26:53).
• Relapsing weight-gain is regulated by the microbiome, including by regulating genes involved in energy expenditure (26:53).
• The microbiome remains stable over time, such that consistent long-term diet changes are required for profound health effects (30:20).
• Unlike micronutrients, small fibers are digested solely by gut bacteria – but consumption of either has sustained effects on glucose metabolism (33:38).
• Artificial sweeteners currently being examined by Segal Lab (34:52).
• What DayTwo does as a company and personalized services to expect in near future (35:20).
• Providing actionable information for glucose management (42:00).
• The basic data inputs for using the DayTwo service and integrating lifestyle into personalized diet feedback (43:26).
• Instead of being a diagnostic company, DayTwo offers recommendations under a predictive model (45:52).
• Where DayTwo microbiome testing and output to users stands out – comparison with competition companies (46:38).
• DayTwo collaborates with the Mayo Clinic to replicate the Israeli microbiome study on US population – calibrating the algorithm for American foods (50:59).
• DayTwo’s success story in Israel, public recognition, service available for pre-order in the US (53:15).
• Plans for bringing DayTwo to the UK and European markets after first tackling the US market (55:24).
• DayTwo US release is not dependent on the Mayo Clinic trial, but more data means continuous predictive algorithm improvement (57:34).
• Reasons why numerous lab testing companies operate in Arizona (58:53).
• Pricing of DayTwo services and a lower US pre-order price (59:42).
• DayTwo takes a direct to consumer approach – offering customizable nutrition advice delivery for different individuals (1:01:51).

Sunny_Bunny_

Blood sugar is fascinating.
I tested at 68 this morning after having 2 cups of coffee with about 3Tbs of half n half.
Went to photograph a house for work. So got about 2000 steps in leisurely then drive 30 minutes home.
At that point I hadn't eaten and it was almost hours later.
It was 100. I had small urine ketones too. But they're always lower early in the day especially if i had 2-3 cups of coffee.
I guess the little activity brought it up.
I've been tracking much more frequently because I want to see what MySugr estimates my A1c at. I've never had one so I have nothing to compare it against.
Just total curiosity. But I'm learning more and more from this simple experiment.

RalfLott

Sunny_Bunny_ wrote: »

Blood sugar is fascinating.
I tested at 68 this morning after having 2 cups of coffee with about 3Tbs of half n half.
Went to photograph a house for work. So got about 2000 steps in leisurely then drive 30 minutes home.
At that point I hadn't eaten and it was almost hours later.
It was 100. I had small urine ketones too. But they're always lower early in the day especially if i had 2-3 cups of coffee.
I guess the little activity brought it up.
I've been tracking much more frequently because I want to see what MySugr estimates my A1c at. I've never had one so I have nothing to compare it against.
Just total curiosity. But I'm learning more and more from this simple experiment.

Keep us posted!