Personalizing Nutrition Based on Genetics?

TX_Bluebonnet
TX_Bluebonnet Posts: 244 Member
edited November 18 in Social Groups
I watched this video and thought I might give this a try for informational and nutritional purposes, but want to get some feedback from you guys first. If I do this I'd like to buy it today while it's on sale for $79 (reg $99) + 9.95 shipping. Plus the cost to generate the report from the raw data for $5.00.

https://youtu.be/bVV2RFEiqN4

Step one is to purchase a DNA saliva test kit at 23andme.com. Step two involves uploading the raw DNA data at promethease.com.

Replies

  • Dragonwolf
    Dragonwolf Posts: 5,600 Member
    I haven't done it myself, but I'm not opposed to the idea. To me, it makes sense to gather objective data like that and customize one's way of eating based on the information. That's essentially the core of the ancestral health movement, really.
  • TX_Bluebonnet
    TX_Bluebonnet Posts: 244 Member
    Thanks, @Dragonwolf! I hadn't heard of an ancestral health movement. I just did some googling and see there's an Ancestral Health Society. I'm going to do some more poking around.
  • Violet_Flux
    Violet_Flux Posts: 481 Member
    Interesting stuff, thanks for posting it @TXbluebonnet2017!

    I had my DNA done at 23andme back in January, so I just tried out the promethease thing. For only $5 I figured it was worth a shot, since I already have my raw dna data.

    The report is quite big and there's lots of stuff in it that would give hypochondriacs loads of stuff to worry about! :smile: Mine came back with 368 'bad' results, and over 5000 'good' ones.

    I do kind of question how they determine 'good' from 'bad' though -- one jumped out at me, was labeled as 'bad' but said my risk of CVD is only 0.72x compared to the 'normal' SNP.

    Anyways, it's a ton of data, it'll take hours to go through the 'bad' stuff, days to go through the 'good' ones.
  • bametels
    bametels Posts: 950 Member
    @TXbluebonnet2017 You can buy it on Amazon and get it for the same price but with free 1-day shipping.
  • RalfLott
    RalfLott Posts: 5,036 Member
    I watched this video and thought I might give this a try for informational and nutritional purposes, but want to get some feedback from you guys first. If I do this I'd like to buy it today while it's on sale for $79 (reg $99) + 9.95 shipping. Plus the cost to generate the report from the raw data for $5.00.

    https://youtu.be/bVV2RFEiqN4

    Step one is to purchase a DNA saliva test kit at 23andme.com. Step two involves uploading the raw DNA data at promethease.com.

    Good sleuthing, @TXbluebonnet2017!

    Rhonda Patrick has made a lot of great vids, and she makes a good case for. genetic testing.
  • TX_Bluebonnet
    TX_Bluebonnet Posts: 244 Member
    Steph_Maks wrote: »
    Interesting stuff, thanks for posting it @TXbluebonnet2017!

    I had my DNA done at 23andme back in January, so I just tried out the promethease thing. For only $5 I figured it was worth a shot, since I already have my raw dna data.

    The report is quite big and there's lots of stuff in it that would give hypochondriacs loads of stuff to worry about! :smile: Mine came back with 368 'bad' results, and over 5000 'good' ones.

    I do kind of question how they determine 'good' from 'bad' though -- one jumped out at me, was labeled as 'bad' but said my risk of CVD is only 0.72x compared to the 'normal' SNP.

    Anyways, it's a ton of data, it'll take hours to go through the 'bad' stuff, days to go through the 'good' ones.

    Ha, the bolded above made me laugh. I admit, I'll be a bit nervous about the results, but hopefully can keep everything in perspective.
  • TX_Bluebonnet
    TX_Bluebonnet Posts: 244 Member
    edited May 2017
    bametels wrote: »
    @TXbluebonnet2017 You can buy it on Amazon and get it for the same price but with free 1-day shipping.

    Oh, great, thanks for the tip. I'll definitely check that out.

    ETA: Ordered it. And saved an additional 10% with my Amex Amazon promo. Thanks again!!
  • TX_Bluebonnet
    TX_Bluebonnet Posts: 244 Member
    RalfLott wrote: »

    Good sleuthing, @TXbluebonnet2017!

    Rhonda Patrick has made a lot of great vids, and she makes a good case for. genetic testing.

    Thanks. She's not exactly a slow talker, but I really like what she's got to say, so I'll be checking out her other videos soon.
  • bametels
    bametels Posts: 950 Member
    edited May 2017
    bametels wrote: »
    @TXbluebonnet2017 You can buy it on Amazon and get it for the same price but with free 1-day shipping.

    Oh, great, thanks for the tip. I'll definitely check that out.

    ETA: Ordered it. And saved an additional 10% with my Amex Amazon promo. Thanks again!!

    I was glad to see your post because I have thought about doing this for a long time. I had read about the Mother's Day discount but had forgotten about it.

    I'm a bit unsure as to whether you get (and if so can use) the data from the $99 test to upload to Promethease because of changes to what they are now allowed to share by law resulting in their adding the option of a limited health report at twice the price. When I looked at some of the comments posted to the Rhonda Patrick video, I noticed that some other people had, and posted, this same question, but she did not respond.

  • RalfLott
    RalfLott Posts: 5,036 Member
    bametels wrote: »
    @TXbluebonnet2017 You can buy it on Amazon and get it for the same price but with free 1-day shipping.

    Oh, great, thanks for the tip. I'll definitely check that out.

    ETA: Ordered it. And saved an additional 10% with my Amex Amazon promo. Thanks again!!

    Amex discount? ??
  • TX_Bluebonnet
    TX_Bluebonnet Posts: 244 Member
    bametels wrote: »
    bametels wrote: »
    @TXbluebonnet2017 You can buy it on Amazon and get it for the same price but with free 1-day shipping.

    Oh, great, thanks for the tip. I'll definitely check that out.

    ETA: Ordered it. And saved an additional 10% with my Amex Amazon promo. Thanks again!!

    I was glad to see your post because I have thought about doing this for a long time. I had read about the Mother's Day discount but had forgotten it.

    I'm a bit unsure as to whether you get (and is so can use) the data from the $99 test to upload to Promethease because of changes to what they are now allowed to share by law resulting in their adding the option of a limited health report at twice the price. When I looked at some of the comments posted to the Rhonda Patrick video, I noticed that some other people had, and posted, this same question, but she did not respond.
    bametels wrote: »
    bametels wrote: »
    @TXbluebonnet2017 You can buy it on Amazon and get it for the same price but with free 1-day shipping.

    Oh, great, thanks for the tip. I'll definitely check that out.

    ETA: Ordered it. And saved an additional 10% with my Amex Amazon promo. Thanks again!!

    I was glad to see your post because I have thought about doing this for a long time. I had read about the Mother's Day discount but had forgotten it.

    I'm a bit unsure as to whether you get (and is so can use) the data from the $99 test to upload to Promethease because of changes to what they are now allowed to share by law resulting in their adding the option of a limited health report at twice the price. When I looked at some of the comments posted to the Rhonda Patrick video, I noticed that some other people had, and posted, this same question, but she did not respond.

    I didn't read all the comments in the video and must have missed those concerns. @Steph_Maks was able to get her report, so seems like it works fine.
  • TX_Bluebonnet
    TX_Bluebonnet Posts: 244 Member
    RalfLott wrote: »
    bametels wrote: »
    @TXbluebonnet2017 You can buy it on Amazon and get it for the same price but with free 1-day shipping.

    Oh, great, thanks for the tip. I'll definitely check that out.

    ETA: Ordered it. And saved an additional 10% with my Amex Amazon promo. Thanks again!!

    Amex discount? ??

    It's part of a promo from when I applied for my card... 10% off Amazon purchases for 6 months.
  • bametels
    bametels Posts: 950 Member
    @Steph_Maks Did you use the 23andme Ancestry service data for the Promethease report or did you have to purchase and use the Health and Ancestry service data? Perhaps they send just one set of data but run two separate reports for Health and Ancestry.
  • Violet_Flux
    Violet_Flux Posts: 481 Member
    bametels wrote: »
    I'm a bit unsure as to whether you get (and if so can use) the data from the $99 test to upload to Promethease because of changes to what they are now allowed to share by law resulting in their adding the option of a limited health report at twice the price. When I looked at some of the comments posted to the Rhonda Patrick video, I noticed that some other people had, and posted, this same question, but she did not respond.

    I am pretty sure that you can download the full genetic data file from 23andme regardless of the limitations they or the government have imposed on them, and regardless of whether you pay for the medical reports or not. I am sure they sequence everything, then just limit what reports you can see on their website.

    I'm in Canada so not subject to their government-imposed restrictions, but I did shell out the $ for the full medical report. Even so, they conceal some medical information from me in the regular report screens. However if you know what SNP number to look up, you can still find the raw data and figure out things for yourself.
  • bametels
    bametels Posts: 950 Member
    @Steph_Maks Thanks for sharing this information. I clearly need to do some more reading about all this.
  • Violet_Flux
    Violet_Flux Posts: 481 Member
    I've spent the past 2 hours reading the report, I found there's a lot of duplication in it. Like if a particular entry involves multiple SNPs then you get the same entry multiple times, once for each of the related SNPs.

    Eg. out of the 368 'bad' entries I had, I must have seen '7x less likely to respond to antidepressants' at least a half dozen times. (That stuck out at me because I've been on antidepressants in the past and they never seemed to do me much good hehe.)

    You also have to be mindful when you read it, like if it says you have 1.8x more chance of getting X, that doesn't mean you've got an 80% chance of getting it. That just means your particular risk factor is 1.8x the average. So if the average risk is 0.00001% then your risk is 0.000018%. They don't mention this, at least anywhere obvious, but if you aren't aware of it then some of the results could be scary.
  • bametels
    bametels Posts: 950 Member
    @Steph_Maks Thanks so much for sharing this information!
This discussion has been closed.