Trying something new!

MmmDrop
MmmDrop Posts: 160 Member
edited December 2024 in Social Groups
Received my 6 week lab results after starting on 1.5 grains of Armour, off of a dose of 150mcg Synthroid + 25mcg Cytomel - and it didn't look too good. My FT4 was super low - under the normal range, but strange thing is that my TSH still hadn't budged and was still showing as super suppressed. It had actually dropped a little from 0.02 to 0.07!! For the last 4 weeks, I've had serious hypo feelings, depression, super dry skin, super puffiness, gained back 15 pounds, extreme exhaustion.... that TSH level just doesn't correspond whatsoever with how I've been feeling.

I got mad at first - but then did some thinking, and realized that I have had a problem with my TSH acting all screwy since my endo at the time put me on Metformin. Btw - I wasn't then, or now am not a diabetic. The endo I was seeing said my blood sugars looked a little off - but since then have been completely normal. Before the Metformin, I had gone all the way up to 200mcg with my TSH still in the normal ranges, looking for that magic number that made me feel well. After the Metformin, my TSH was constantly suppressed, and every doctors visit afterwards, my dose was always downgraded no matter how hypo I felt.

After doing some research, I found valid case studies in the Journal of Endocrinology and Metabolism, that supported my theory that Metformin was causing my TSH to become suppressed without causing any clinical symptoms of hyperthyroidism. I took this info to my new doctor yesterday, and he was actually pretty amazed as he had never heard of that before! He thanked me for teaching him something new, said that there was no real reason he could see for having me on the medicine to begin with, and was really excited to see what happens with my TSH.

Anyways - I'll keep you all updated! I go back in 5 weeks for labs again, and I'm pretty excited to see what happens with my TSH. I just don't see how my TSH could be telling the truth. I do realize that the TSH isn't a thyroid hormone, but a pituitary hormone... but still... I just don't understand, and want to know why. :D

Replies

  • debbylee22
    debbylee22 Posts: 456 Member
    Very interesting. So sorry you're not feeling well. And happy for you that you can get rid of an unneeded medication. Sure hope it works for you.
    I got puffiness & water retention as a reaction to supplemental treatment of my adrenals. The NP said it is a reaction from the adrenals, as they are in a bad state... wondering how long it will take to get them back to good & get rid of the puffiness! So annoying, when its so hard to lose 1 lb!
    Hope things turn around for you!
  • MmmDrop
    MmmDrop Posts: 160 Member
    Thanks :D I'm almost positive I'm right! There's so much research out there that's backing up my theory!

    When I was looking up case studies to take to my doctor, I ran across one that listed a bunch of different medications that can significantly effect a person's TSH.
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