Nausea and diarrhea are two very common side effects when starting metformin. This can last a few days, or up to a few weeks (unfortunately). If your symptoms are severe, you may want to talk to your doctor about if it's ok for you to take 1 dose a day for a while to start while your body gets used to things.

I had this reaction for the full 10 years I was on it. Finally I told my Dr that it was just as bad then as day 1, and that I felt like I had broken glass and razor blades running through my gut, and that I was gonna quit taking it, he changed me over to extended release, same symptoms! Glipizide does the same thing. Now I am on insulin, 5 shots a day, but I would rather have to take those shots, than have my gut hurt like it did.

I hope you don't have the same as I did, and that your body adjusts quickly.:bigsmile:

I tend to have "tummy troubles" anyway, and Metformin just made it 10 times worse. I was on it for over 6 months, and finally my doctor switched me over to Januvia. If you don't adjust to it, ask for something else. Although I will say that Metformin works nicely on the blood glucose. Just not so great with the tummy. Good luck!