toadqueen wrote: »

@SteveKroll. I haven't yet found the source. I'm on my phone and was on the computer yesterday. Sorry group for being lazy...

Here's a different article on the subject that is also exciting. Long-term effects of a ketogenic diet in obese patients
Hussein M Dashti, MD PhD FICS FACS, Thazhumpal C Mathew, MSc PhD FRCPath, [...], and Naji S Al-Zaid, BSc PhD from NIH. I don't know how to copy it better

wabmester wrote: »

Hang in there, @PasPlus. High LDL seems to be a not-uncommon side effect of the diet. Phinney gives one possible explanation.

Taubes addressed it recently:
http://carbfreenation.com/blog/2015/7/23/carb-free-nation-interviews-gary-taubes-author-of-why-we-get-fat-and-what-to-do-about-it

The avant garde of lipidologists will tell you LDL particle number (LDL-P) is the best predictor of heart disease risk. LDL-P tracks well with small, dense LDL and with ApoB, which is the protein component of LDL and VLDL particles. LDL-P also tracks pretty well with insulin resistance, although when it’s divergent – i.e., LDL-P is high, but there’s no insulin resistance – we really don’t know what that means clinically.

But when people go on ketogenic or paleo diets, often both their LDL and LDL-P will go up, even as other risk factors related to insulin resistance factors will resolve. There are a lot of people walking around on low carb diets, with no insulin resistance; their triglycerides are low, HDL is high, glucose tolerance is excellent, but their LDL-P is also high. The lipidologists I respect will give that person advice to stay on low carb, but probably prescribe a statin to control the LDL-P. But they will also say they don’t really know what this portends for risk and are just erring on the side of caution.

And the problem is that we don’t really know what a high LDL-P means in the context of a ketogenic population that has no insulin resistance. The epidemiological studies that determined LDL-P is the best predictor of cardiovascular risk are done in free-living populations of Americans eating the so-called Standard American Diet. Now that we’ve removed the insulin resistance, what does the LDL-P mean? The lipidologists don’t really know. I certainly don’t.

Statins seem to be effective in bringing LDL-P down. I do know some ketogenic dieters who have been successful lowering their LDL-P without statins, by modulating their diet, removing saturated fats, adding some low-GI carbs, chewing hemp seeds, even using red rice or probiotics. Some ketogenic dieters get their calcium scores and artery scans, showing zero calcium in their arteries, and have a plan to ignore their LDL-P, because whatever is happening they see it is not atherosclerotic.

He's working with Peter Attia, who recently wrote this:
http://eatingacademy.com/cholesterol-2/random-finding-plus-pi

I realize there is a contingent within the LCHF community who argue that traditional biomarkers of coronary risk—such as LDL-C or its superior cousin LDL-P—“don’t matter” if one is on a low carb or ketogenic diet. Maybe they are right. I guess time will tell. But I am not convinced, at least not yet. As a doctor I can’t look a patient in the eye and tell them a sky-high LDL-P is ok because they don’t eat carbohydrates. So if you’re following such a diet, and your LDL-P goes through the roof, I’d urge you to consider a variation of the diet.

Specifically, he recommends changing the types of fat you consume.

If it were me, I'd take the Attia approach. You now have a baseline. Experiment, and get rechecked.