New study on artificial sweeteners affecting glucose tolerance
cstehansen
Posts: 1,984 Member
This is a very alarming study if you use artificial sweeteners.
https://chriskresser.com/how-artificial-sweeteners-wreak-havoc-on-your-gut/?utm_source=ChrisKresser.com&utm_medium=email&utm_term=0_e7d56abf8a-ee9c9ca3ac-95902905&utm_content&utm_campaign=ee9c9ca3ac-EMAIL_CAMPAIGN_2016_11_09&mc_cid=ee9c9ca3ac&mc_eid=56daae840f
Here is a short quote from near the end:
"in just this short week-long period, four out of seven individuals had already developed significantly poorer glycemic responses (NAS responders) and pronounced changes in microbiota composition. The remaining three individuals had no change (NAS non-responders)."
The quick summary is in mice all of them had a change in gut microbe when using these non-caloric artificial sweeteners (NASs) which correlated to decreased glucose tolerance. In reviewing data from human studies, there was a correlation between the use of NAS and reduced glucose tolerance. And in the first human experiment directly testing this, 4 out of 7 healthy human subjects showed a change in gut microbe and reduced glucose tolerance in just one week where they were given the FDA's max "safe" amount per day split among 3 equal servings.
Clearly there needs to be more research, but this, along with the dramatic change in SAD to high carb diets would easily explain why diabetes and other metabolic diseases have skyrocketed over the last few decades.
https://chriskresser.com/how-artificial-sweeteners-wreak-havoc-on-your-gut/?utm_source=ChrisKresser.com&utm_medium=email&utm_term=0_e7d56abf8a-ee9c9ca3ac-95902905&utm_content&utm_campaign=ee9c9ca3ac-EMAIL_CAMPAIGN_2016_11_09&mc_cid=ee9c9ca3ac&mc_eid=56daae840f
Here is a short quote from near the end:
"in just this short week-long period, four out of seven individuals had already developed significantly poorer glycemic responses (NAS responders) and pronounced changes in microbiota composition. The remaining three individuals had no change (NAS non-responders)."
The quick summary is in mice all of them had a change in gut microbe when using these non-caloric artificial sweeteners (NASs) which correlated to decreased glucose tolerance. In reviewing data from human studies, there was a correlation between the use of NAS and reduced glucose tolerance. And in the first human experiment directly testing this, 4 out of 7 healthy human subjects showed a change in gut microbe and reduced glucose tolerance in just one week where they were given the FDA's max "safe" amount per day split among 3 equal servings.
Clearly there needs to be more research, but this, along with the dramatic change in SAD to high carb diets would easily explain why diabetes and other metabolic diseases have skyrocketed over the last few decades.
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cstehansen wrote: »This is a very alarming study if you use artificial sweeteners.
https://chriskresser.com/how-artificial-sweeteners-wreak-havoc-on-your-gut/?utm_source=ChrisKresser.com&utm_medium=email&utm_term=0_e7d56abf8a-ee9c9ca3ac-95902905&utm_content&utm_campaign=ee9c9ca3ac-EMAIL_CAMPAIGN_2016_11_09&mc_cid=ee9c9ca3ac&mc_eid=56daae840f
Here is a short quote from near the end:
"in just this short week-long period, four out of seven individuals had already developed significantly poorer glycemic responses (NAS responders) and pronounced changes in microbiota composition. The remaining three individuals had no change (NAS non-responders)."
The quick summary is in mice all of them had a change in gut microbe when using these non-caloric artificial sweeteners (NASs) which correlated to decreased glucose tolerance. In reviewing data from human studies, there was a correlation between the use of NAS and reduced glucose tolerance. And in the first human experiment directly testing this, 4 out of 7 healthy human subjects showed a change in gut microbe and reduced glucose tolerance in just one week where they were given the FDA's max "safe" amount per day split among 3 equal servings.
Clearly there needs to be more research, but this, along with the dramatic change in SAD to high carb diets would easily explain why diabetes and other metabolic diseases have skyrocketed over the last few decades.
That's a pretty arresting tale. Thanks for the ref!
Did they use the whole range of NAS products now on the market and reach the same conclusion for all of them?* It's hard to imagine that erythritol is as bad as all the other x-itols over a range of species and test subjects...
I suspect the combined effect of every nanogram of NAS products since the good ol' days of Tab and Fresca is but a drop of water on the hot rock that has the ADA's immovable advice to T2Ds to eat yer carbs.
*It looks like the study only reviewed
saccharin (Sweet’n Low), aspartame (Equal, NutraSweet and Canderel), and sucralose (Splenda), but neither Erythritol nor Xylitol. (And of course, not stevia.)1 -
I figured this is pretty important because these are the ones that are in all the diet/no calorie drinks which I know are a staple for many with this WOE.1
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Yes. It's nasty stuff! That's why I have them up. Plus they made me feel hungry all the time. I figured that was a gut microbe response or something.
I don't have that happen with liquid stevia or liquid erythritol2 -
Maybe I really lucked out, am one of the three not affected. Really dodged a bullet on that one.3
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Shoot. I've been added diet cola back into my diet. Not a great choice I know but I (wrongly) justified it as a less harmless comfrort food - compared to my past anyways. This made me rethink my actions. Gave me that extra kick in the rear to do what I know I should rather than what I want to do.
Thanks for posting this.3 -
Shoot. I've been added diet cola back into my diet. Not a great choice I know but I (wrongly) justified it as a less harmless comfrort food - compared to my past anyways. This made me rethink my actions. Gave me that extra kick in the rear to do what I know I should rather than what I want to do.
Thanks for posting this.
It's a challenge....
A fizzy, sweet drink that doesn't mess with you.
+ Sparkling water
+ Stevia (w or w/o Erythritol)
+ Flavoring, like pure vanilla
.... hmmmm
something missing.....
+Booze!
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What I've been doing lately is making flavored iced teas. I buy these kinds of teas
And I add 1 family sized Lipton tea bag and 2 of whatever flavor I want to a pot of water and bring to a boil for a minute. Then pour over ice in a pitcher. Add liquid stevia and/or erythritol for a touch of sweetness. Not southern sweet tea level... I usually have enough to make 1.5 to 2 pitchers.
It gets me looking forward to having a glass and it's not just plain old boring water.
And there are so many possible flavors.3 -
Sunny_Bunny_ wrote: »What I've been doing lately is making flavored iced teas. I buy these kinds of teas
And I add 1 family sized Lipton tea bag and 2 of whatever flavor I want to a pot of water and bring to a boil for a minute. Then pour over ice in a pitcher. Add liquid stevia and/or erythritol for a touch of sweetness. Not southern sweet tea level... I usually have enough to make 1.5 to 2 pitchers.
It gets me looking forward to having a glass and it's not just plain old boring water.
And there are so many possible flavors.
That's such a great idea! Thank you!0 -
So does that make Truvia off limits? Liquid Stevia tastes bitter to me rather than sweet (it's an MS thing from trigeminal neuralgia causing numbness on part of my lips and tongue). I've used Truvia in my fat bombs (aka power poppers). I've changed my morning keto coffee to not include any sweetener, but I do like a fat bomb most days and use them if my fat is low for the day.1
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So does that make Truvia off limits? Liquid Stevia tastes bitter to me rather than sweet (it's an MS thing from trigeminal neuralgia causing numbness on part of my lips and tongue). I've used Truvia in my fat bombs (aka power poppers). I've changed my morning keto coffee to not include any sweetener, but I do like a fat bomb most days and use them if my fat is low for the day.
Truvia is stevia and erythritol, neither of which were included in the study.
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I'm dying to post this study over on the debate forum, but It'll probably be picked apart and I'll get eaten alive
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SuperCarLori wrote: »Maybe I really lucked out, am one of the three not affected. Really dodged a bullet on that one.
I'm not trying to bring you down, but if you are staying keto, you may not know if this is affecting you since you aren't taking in the glucose to see how your body processes it.
One study with 7 people isn't enough to close the book. This may turn out to be a big deal. It may turn out that it only affects a small number of people.3 -
@KnitOrMiss, @RalfLott & @Sunny_Bunny_ - I thought I would call you out specifically since you are the ones that seem as obsessed (or in the case of @KnitOrMiss possibly more obsessed) with medical research as I am. Given the findings of this in relation to the gut microbiome and the improvement they found in mice when giving them antibiotics, do you think taking a probiotic or prebiotic (I am not well versed on either) could help to reverse damage done by these artificial sweeteners?
Also, I was wondering if more people weren't affected because of the trace amounts of antibiotics we get from eating the standard raised meat. Given roughly 80% of all antibiotic consumption in the US is for commercially raised animals to keep them from getting sick, at least some of that has got to end up in the meat we are eating.0 -
Shoot. I've been added diet cola back into my diet. Not a great choice I know but I (wrongly) justified it as a less harmless comfrort food - compared to my past anyways. This made me rethink my actions. Gave me that extra kick in the rear to do what I know I should rather than what I want to do.
Thanks for posting this.
It's a challenge....
A fizzy, sweet drink that doesn't mess with you.
+ Sparkling water
+ Stevia (w or w/o Erythritol)
+ Flavoring, like pure vanilla
.... hmmmm
something missing.....
+Booze!
LOL A nice alternative.
Yuck. I need to spell check better. My old high school English teachers would be ashamed.1 -
Christine_72 wrote: »I'm dying to post this study over on the debate forum, but It'll probably be picked apart and I'll get eaten alive
LOL I thought the same thing!3 -
Random fun fact: erythritol will kill your dog, however it has no toxic effect on you. BAT stimulating thermogenics will turn your pet hamster into a miniature fat furnace. It will do almost nothing for you.
I'll worry about this when it's replicated in humans. Until then, there's just too much room for exaggeration and unnecessary freak out.3 -
cstehansen wrote: »Also, I was wondering if more people weren't affected because of the trace amounts of antibiotics we get from eating the standard raised meat. Given roughly 80% of all antibiotic consumption in the US is for commercially raised animals to keep them from getting sick, at least some of that has got to end up in the meat we are eating.
Animals have to be off antibiotics for long enough that they are out of their system before slaughter. You are not being exposed to any from eating meat.6 -
Argh. I am one of the few people who have a problem with Stevia apparently. I have low(er) blood sugar to start with, and stevia TANKS it. Like I will be 70-80 normally and if I drink a bottle of tea with stevia I will hit 40 in no time and nearly black out.
Monk fruit is my go-to most of the time, with sucralose some ... I minimize sucralose because I OD'd on it years ago (i.e. 40 packs a day) and ended up being diagnosed with fibromyalgia (which I did not have) because of the side effects. So I keep it minimal now, but its one of the few I can handle the taste of.1 -
Argh. I am one of the few people who have a problem with Stevia apparently. I have low(er) blood sugar to start with, and stevia TANKS it. Like I will be 70-80 normally and if I drink a bottle of tea with stevia I will hit 40 in no time and nearly black out.
Monk fruit is my go-to most of the time, with sucralose some ... I minimize sucralose because I OD'd on it years ago (i.e. 40 packs a day) and ended up being diagnosed with fibromyalgia (which I did not have) because of the side effects. So I keep it minimal now, but its one of the few I can handle the taste of.
You didn't have it, because it's usually given as a monkeyshit diagnosis when a doctor has no idea what's actually wrong with you. My mom was diagnosed with the same *kitten*, then it was suddenly cured when her last husband left her, and she couldn't mooch off of his paycheck anymore.1 -
Christine_72 wrote: »I'm dying to post this study over on the debate forum, but It'll probably be picked apart and I'll get eaten alive
Double dog dare ya!2 -
Christine_72 wrote: »I'm dying to post this study over on the debate forum, but It'll probably be picked apart and I'll get eaten alive
Double dog dare ya!
Will you protect me?
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Christine_72 wrote: »Christine_72 wrote: »I'm dying to post this study over on the debate forum, but It'll probably be picked apart and I'll get eaten alive
Double dog dare ya!
Will you protect me?
Geez... From mods or framers?0 -
Christine_72 wrote: »Christine_72 wrote: »I'm dying to post this study over on the debate forum, but It'll probably be picked apart and I'll get eaten alive
Double dog dare ya!
Will you protect me?
Geez... From mods or framers?
Framers
I'm not going to start a thread, I may slip it into an already active topic on AS's.0 -
Christine_72 wrote: »Christine_72 wrote: »Christine_72 wrote: »I'm dying to post this study over on the debate forum, but It'll probably be picked apart and I'll get eaten alive
Double dog dare ya!
Will you protect me?
Geez... From mods or framers?
Framers
I'm not going to start a thread, I may slip it into an already active topic on AS's.
Lots of AS's topics to choose from .... let us know?
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Mod Hat:
I sure hope we aren't talking about the Main Forums. And definitely not formally organizing activity there.
That's one of the things we were falsely accused of doing in here. (Going in here to meet, and deliberately target threads and/or other members, then organizing an effort to all go into the Main Forums to cause problems/drama.)
So further discussions about the aforementioned activity need to be taken to PMs. Whether or not there is malice intended, which I'm sure there is not. Still have to say it anyway.
And of course we don't as a group condone such activity. Blah..blah...blah.5 -
For the record I posted this in the place where I believed it would be read by those who would be most helped by it and be most open to reading scientific data that could actually help them in their pursuit of better health. (Was that sucking up enough?)
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@cstehansen -
No, you're in the right place!
To get back to your question about pre/probiotics rightng the sins of sucralose, I really wish I had something close to an answer, but I'll be happy to sniff around.
I finally found an excellent nutritionist (who'd'a thunk it?), who thinks we should be taking them daily - and rotating them - daily. I'll run the questionnaire by her next visit.
You also wondered about the effects of consuming antibiotics (not to mention hormones) in animal products. I'll add that question to the list. I suspect people have such strong feelings pro- or contra-meat that every study is destined to be assailed before the ink is dry.
But there's no way I'm eating a fast food burger with bacon for dessert until someone proves Hormel served that stuff to our cavemen ancestors.
PS Thx for including me, however undeserved, in such august company.
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Shoot. I've been added diet cola back into my diet. Not a great choice I know but I (wrongly) justified it as a less harmless comfrort food - compared to my past anyways. This made me rethink my actions. Gave me that extra kick in the rear to do what I know I should rather than what I want to do.
Thanks for posting this.
It's a challenge....
A fizzy, sweet drink that doesn't mess with you.
+ Sparkling water
+ Stevia (w or w/o Erythritol)
+ Flavoring, like pure vanilla
.... hmmmm
something missing.....
+Booze!
@RalfLott - I just wanted to say that Zevia brand sodas use Stevia, Erythritol, and I think Monk Fruit. They're decent as far as the flavors I have tried, but expensive. Far better for a temporary soda fix than a traditional diet in my own opinion. Paid less than $0.75 per 12 oz can, so I guess not that bad, just more expensive than "sodas." That being said, Ozarka has unsweetened "fizzy" water, as does LaCroix, and I like doing those with a few drops of stevia on occasion, but it's nice to have an option like Zevia with beet root for color and etc.0 -
Gallowmere1984 wrote: »Argh. I am one of the few people who have a problem with Stevia apparently. I have low(er) blood sugar to start with, and stevia TANKS it. Like I will be 70-80 normally and if I drink a bottle of tea with stevia I will hit 40 in no time and nearly black out.
Monk fruit is my go-to most of the time, with sucralose some ... I minimize sucralose because I OD'd on it years ago (i.e. 40 packs a day) and ended up being diagnosed with fibromyalgia (which I did not have) because of the side effects. So I keep it minimal now, but its one of the few I can handle the taste of.
You didn't have it, because it's usually given as a monkeyshit diagnosis when a doctor has no idea what's actually wrong with you. My mom was diagnosed with the same *kitten*, then it was suddenly cured when her last husband left her, and she couldn't mooch off of his paycheck anymore.
I completely agree
I did have a *kitten* load of symptoms that are typical of that diagnosis, but ALL OF THEM went away when I cut out sucralose (after reading a website of sucralose side effects that matched up perfectly). Since then I had a friend diagnosed with lupus who turned out to be intolerant to wheat gluten, another friend "reverse" her fibro diagnosis by cutting out diet soda with aspartame (all she drank all day for many years), etc etc.
I dont doubt people have legitimate symptoms indicating something is wrong (except for your mom, she was just greedy ). I just think doctors dont acknowledge or have the time to devote to finding out what food sensitivity or other issue might be the real underlying cause, so fibro is a "diagnosis" they give so the person has a name they can google and commisserate. My doctor literally PUSHED that on me multiple times as a way to get me out of his office. I refused to accept it because everything I read said it was an "elimination" diagnosis - i.e. we dont know what is wrong, have eliminated everything obvious, and want you to feel like you know what is wrong so we give you this.
Now whenever i get a "symptom", I immediately start playing with my diet and checking the sub-ingredients and doing experiments until I figure it out myself.3 -
Cut out the sweets and eat the meats! Keto on!!!1
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