What's the point?

I agree with those who think it's hormonal...I took welbutrin to stop smoking and take metformin, they, in regards weight gain/loss, should cancel each other out, metformin has been shown to help people lose weight, not a lot of it, but some.

Also, as another posted, Log EVERYTHING that goes into your mouth and walk, walk walk...I know, I hate walking, but I walk at least an hour a day/5 days/week, start by walking away from your house for 5 mins then walk back...that's ten minutes...then go a minute farther each day. It doesn't even have to be fast, just walk.

Print out your diets, exercise, etc and show your doctor how you've been trying. I would beg for more tests!

Those ten points are very valid, appreciate that, being strict and just doing it!

Just saying.... Metformin and Wellbutrin are awful for me. I don't take either. I would get off that crap and work on eating clean, lower carb for your obvious insulin issue (since you're on Metformin) and lower sodium. See what happens.

I didn't lose, in fact I gained, and I tried for 15 years. We are all different. I had thyroid and adrenal fatigue issues and once those were addressed there was still no magic pill. For me it was taking a good look at what I was eating, AN HONEST LOOK, people do play mental accounting games and incorrect estimates in logging, all people do. For me it didn't seem fair, but I needed to eat less. It was hard. It still took two years. But once you find the right amount of calories for a true calorie deficit and stick with it long enough the weight will drop. This is what I finally had to do ==> http://www.myfitnesspal.com/topics/show/740340-i-lost-60-lbs-at-age-51-anyone-can-any-workout

Your body loses weight in chunks, not linear. I have found that you can do everything right and your weight loss seems to plateau but if you are patient and keep exercising and eating at a deficit (however slight) you will lose it, it will suddenly "whoosh". There are so many variables for the scale; water retention, digestion, hormones, allergies, sodium, carbs, water intake, DOMS, inflammation, the list goes on. People mistakenly think they lose or gain weight when they eat more or less because of these fluctuations.

Losing weight requires tremendous patience. You will not lose it when you want it or where you want it. The body does its thing. Some apparent plateaus can last a month or so. You cannot make it happen faster. You must focus on two things; calories and exercise. Nothing else matters. Scales and metrics don't matter. The day in and day out grind of exercise and calories are all that matters. It is not very exciting until things fall into place. You get your victories and you ride one victory to the next.

The scale is a trend tool. The scale is good but put it away and only check once a week and only use it as a trend tool. It will fluctuate, it does not matter. Take front side and back progress pictures at least once a month. You will see differences that the metrics won't tell you and it's that little bit of NSV that will keep you going until the next victory.

It's human nature to want to feel like a snow flake, but it really comes down to a simple calorie deficit for everyone.

What is the exact number of calories for you?

We’ve been trying to figure out an exact NUMBER of calories that everyone should be eating, without recognizing that everyone is slightly different. In truth, the calories aren’t the end game. Your body is. So the EXACT amount of Calories that are right for you is the EXACT amount that will allow you to maintain your ideal bodyweight no matter what some calculator or chart says.

In other words, an online calculator might tell you that you need to eat 2,500 calories
per day to maintain your ideal bodyweight. But the only way to know for sure if this is
the right amount for you is to test it out. If you gain weight or can’t lose weight eating
that much, then you know you need to eat less to lose weight no matter how many
calculators and text books say otherwise.

This doesn’t mean your metabolism is broken, it just means the estimate of your needs
was just a bit off.

-John Barban (The Body Centric Calorie Guide from the Venus Index and Adonis Index Manuals)

As other people have noted, a little obsession can be good, but not if it's bringing you down. As an alternative, you might like to look at Paul McKenna's book 'I Can Make You Thin'. It is very short and easy to read, and at less than $8 you can't really go wrong.

http://www.amazon.com/Can-Make-You-Thin-Revolutionary/dp/1402775547/ref=pd_sim_b_1

There is no calorie counting, no nutrition guidance, no numbers and no targets – just four simple rules, plus a hypnotherapy CD to make it easier to follow them. The hypnotherapy is nothing scary, you just put it on your iPod or whatever while you fall asleep.

Paul discourages weighing, instead encouraging you to visualise success and check how your body feels and your clothes fit. You can weigh every two weeks if you really want to.

Although I'm now doing MFP, I previously took two inches off my waistline in a couple of months with this system.

I can get really anxious if I feel that 'it's not working', which can become a self-fulfilling prophecy if you're not careful. Paul's techniques help you to break free of that, partly through the hypnotherapy, which instils positive beliefs without you realising.

Hope that helps. Good luck!