How often should I lift?

^What he said.

What kind of lifting programme are you going to follow? What exercises are you hoping to incorporate into your strength training?

I lift 5 times a week and take 2 days for cardio / rest.

I'm also a martial artist and have lost about 75 lbs so far with about 30 to go.

If you're doing as much MMA training as you indicate and also managing your caloric intake you're gonna have no problem loosing weight. What you're gonna need to do is make sure you set a floor for a couple of nutrients, such as calories and protein so you don't wind up burning up your muscle.

For MMA, Muay Thai or BJJ you need a strong core. If you don't have a strong core you'll eventually get to the point where, for example on a Thai kick, you can out kick the structural stability of your back. So, make core strength job 1. For both your standup and ground game you're gonna need to do some bridges to strengthen your neck. Take those slowly and carefully at first, and you may want to use your hands or a step for assistance. Eventually you'll want to be able to rock back and forth x100 on both front and back bridges a couple of times a week.

I'd also recommend not doing bodybuilding methodology if you're doing martial arts as it will slow you down. You want to go for functional strength and you won't get that from a bodybuilding coach. I'd either do the powerlifting (for the fast twitch muscle fiber activation, explosiveness, tendon strength and speed) that they do at Westside Barbell or go for it with Kettlebell training. Kettlebell will burn about 1k calories per hour, improve your anaerobic threshold and build a strong core, so it's a very good use of your time. (I do both of the above to support my Muay Thai and boxing workouts).

Oh, one other thing. I learned the hard way that you don't want to do too much jumping rope. Jumping rope is excellent for cardio as well as hand & foot speed. In addition, it's good if you're overweight because jumping on your toes gives you an extra shock absorber effect that makes it easier on your knees and ankles than running. HOWEVER, give yourself at least a day for your body to recover between jump rope workouts. I tore the medial head of my gastrocnemius (calf muscle) several times, and it was no fun.

Best of luck, and as they say in Thailand, "Chok de Nai" (Keep your hands up!)

I asked about your routine because if you are (and I think you are?) a beginner to lifting a full body routine 3 days a week is probably the best starting point. It seems to be easier on the body then a split routine. I think a split routine is only suggested when you are considered an intermediate weight lifter.