D level changes with loss of adipose tissue?
silverkitty777
Posts: 10 Member
Changes in circulating vitamin D levels with loss of adipose tissue.
Gangloff, Anne; Bergeron, Jean; Lemieux, Isabelle; Després, Jean-Pierre
Current Opinion in Clinical Nutrition & Metabolic Care
Post Author Corrections: August 16, 2016
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Abstract
Purpose of review: Low vitamin D levels have been extensively reported in obesity. Thus, the pandemic of obesity has been paralleled by a high prevalence of low vitamin D status. Given the well documented associations linking poor vitamin D status to adverse health outcomes (diabetes, cardiovascular disease, cancers, all-cause mortality), a proper understanding of the mechanisms linking excess adiposity to low vitamin D status is key to identify and implement effective interventions to replenish vitamin D levels in obese individuals. In this review, we will discuss recent literature investigating the effects of adipose tissue volume loss through energy restriction and/or physical activity on circulating 25-hydroxyvitamin D [25(OH)D] levels.
Recent findings: Improvements of circulating 25(OH)D levels with adiposity loss through lifestyle interventions without supplementation is being reported by a growing number of studies, including recent randomized controlled trials.
Summary: Low 25(OH)D is one of the metabolic disturbances associated with excess adiposity, particularly visceral adiposity. Recommendations for the treatment of obesity-related vitamin D deficiency should emphasize the role of visceral adiposity loss through healthy lifestyle habits, in conjunction with weight-adjusted vitamin D supplementation, not only to replenish 25(OH)D levels but also to address other visceral adiposity-related disturbances, such as insulin resistance, inflammation, hypertension, and dyslipidemia.
Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.
Gangloff, Anne; Bergeron, Jean; Lemieux, Isabelle; Després, Jean-Pierre
Current Opinion in Clinical Nutrition & Metabolic Care
Post Author Corrections: August 16, 2016
ExpandFavoritePDF
Abstract
Purpose of review: Low vitamin D levels have been extensively reported in obesity. Thus, the pandemic of obesity has been paralleled by a high prevalence of low vitamin D status. Given the well documented associations linking poor vitamin D status to adverse health outcomes (diabetes, cardiovascular disease, cancers, all-cause mortality), a proper understanding of the mechanisms linking excess adiposity to low vitamin D status is key to identify and implement effective interventions to replenish vitamin D levels in obese individuals. In this review, we will discuss recent literature investigating the effects of adipose tissue volume loss through energy restriction and/or physical activity on circulating 25-hydroxyvitamin D [25(OH)D] levels.
Recent findings: Improvements of circulating 25(OH)D levels with adiposity loss through lifestyle interventions without supplementation is being reported by a growing number of studies, including recent randomized controlled trials.
Summary: Low 25(OH)D is one of the metabolic disturbances associated with excess adiposity, particularly visceral adiposity. Recommendations for the treatment of obesity-related vitamin D deficiency should emphasize the role of visceral adiposity loss through healthy lifestyle habits, in conjunction with weight-adjusted vitamin D supplementation, not only to replenish 25(OH)D levels but also to address other visceral adiposity-related disturbances, such as insulin resistance, inflammation, hypertension, and dyslipidemia.
Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.
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Replies
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Anyone check this out yet?0
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...or just get more sunshine...about 20 minutes per day if possible....1
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Interesting. Thanks for the article silverkitty777. I am due to have my vitamin D levels tested again in September and am interested to see if they have risen with weight loss.Return2Fit wrote: »...or just get more sunshine...about 20 minutes per day if possible....
Not really an option after 2 skin cancer surgeries. My usual summer attire is long pants, long sleeved shirt, and hat. Quite stylish!0 -
Plus as we get older the less our skin absorbs from sunshine. The darker your skin is can also affect absorption through sunshine. When I was first diagnosed my level was 9. Last time I checked it was at the very low end of normal.0
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Thanks for posting. I should point out though that this isn't a new study, but a review of existing studies. To me there isn't any argument that obesity is associated with lower vit D levels. Apparently it gets trapped in fat and leads to less bioavailability. Losing weight makes it available again. The inconclusive part is whether taking vit D while dieting helps you lose weight, specifically visceral fat. Maybe, maybe not. Lots of other benefits to taking it so why not?1
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