Advice to losing weight with chronic fatigue and depression?

Yes, no problem. I lost the weight I wanted to lose while in a pretty bad hashimotos outbreak and other endocrine health problems. It all comes down to eating less than your body needs to maintain weight. I do admit though that using a food scale consistently and logging precisely is more difficult if you don't feel well. Are you seeing a good endocrinologist?

I have thyroid issues, and diabetes. High fat helps me a lot.

I see all these low fat diets that demonize dietary fat, and they make me sad, weak, and I quit after the first day.

Eating my peanut butter and coffee with cream keeps me energized and within my calories without being hangry and exhausted.

I don't think high fat works for everyone, but finding what works for you is the difference between success and failure.

Hello. When I first joined MFP several years ago, I lost 35 pounds in 6 months, but most of it came back. I have not gotten back to my all-time high weight, though, and I don't plan to.
I have osteoarthritis in my knees, hips, elbows, and ankles, as well as the beginning stages of spinal stenosis (narrowing of spaces between vertebrae). I have been told that I will need both knees and at least one hip replaced, as well as have a hernia situation repaired, but both surgeons will not do the procedures until I lose at least 50 pounds. My knees and back give me the most pain, but recently my right hip has been complaining, too. I also have depression and anxiety, and am categorized medically as morbidly obese.
I am a fussy eater, and prefer carbs over anything else...and am pre-diabetic, with a diabetic husband (who doesn't really watch what he eats). I log every day, but am frequently in negative numbers by the end of the day. I hate to cook, so I tend to eat more convenience foods, but I do try to choose healthier options. I am a stress eater, and tend to pick up snack foods during the day while driving. I do not work, but I visit my elderly mother in an assisted living facility 4 days out of 5 weekdays, which is what brings on the stress most days. I am a lover of ice cream, pasta, and non-diet soda. I am trying to break the soda habit gradually by drinking diet soda and I recently found a sparkling flavored water that I like -- Vita Ice by Klarbrunn -- it comes in lots of flavors, has no HFCS, no sugar, no Nutrasweet, no calories, no carbs. It does have Sucralose, though.
Because of the arthritis, I can not exercise like a normal person at a gym or Ymca (if I don't want to be in a lot of pain), so I count my movement throughout the day as my daily exercise on MFP. It is probably not technically correct, but it's all that I can do.
I have not found the answer yet, but I do believe it is a LOT of trial and error. We all have to do what it right for us. When I eat a tricky food that is hard to guess by sight, I will either measure or weigh it. These are mostly pasta and cereal, and snack foods like Sun chips.
I wish you nothing but the best in figuring out what is right for you and finding great success. I hope your endocrinologist can help you, too. God Bless!

TMI alert - no thyroid and no uterus. Struggle with energy daily even though thyroid levels are balanced now with meds. Never been right hormonally, always off. It effects my energy, mood and weight. I’m a joy. 😊 But I’m trying again. #notenoughmedsexisttomakemeright

Sans thyroid for 18 years. Realize that getting to a normal weight may be the best treatment for you, meaning it's highly likely that things will get much better as you lose weight.

Hormones are free cycling, so being overweight makes it impossible to maintain hormonal balance. It's akin to dropping a furnace built for a 1000 sqft house into a 2000 sqft house and expecting it to work.