Epigenetic Insights on Nutrition, Hormones and Eating Behavior
GaleHawkins
Posts: 8,159 Member
https://whatisepigenetics.com/epigenetic-insights-on-nutrition-hormones-and-eating-behavior/
"Taken together, these data suggest that eating behavior can be the result of an adverse early life environment and can have a life-long influence on neuroendocrine mechanisms. Maternal obesity and diabetes, and overnutrition in early life will end up in a perinatally acquired malprogramming of appetite and satiety pathways and might contribute to the occurrence of hyperphagia, obesity, and hyperinsulinemia throughout later life."
"Taken together, these data suggest that eating behavior can be the result of an adverse early life environment and can have a life-long influence on neuroendocrine mechanisms. Maternal obesity and diabetes, and overnutrition in early life will end up in a perinatally acquired malprogramming of appetite and satiety pathways and might contribute to the occurrence of hyperphagia, obesity, and hyperinsulinemia throughout later life."
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Replies
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So basically my son is screwed. But I already knew that. ☹️4
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Epigenetics is a very very new field of research and the topic itself and the existence is still up for a lot of debate under scientists. So far research on it has been inconclusive.
The far reaching conclusions that have been associated with it (and you are noting on an epigenetic site) are totally controversial and not proven.15 -
We all have a choice to be all that we can be ,no matter how mom /dad ruined us 😊
🌸I’m not blaming genetics 🌸11 -
GaleHawkins wrote: »https://whatisepigenetics.com/epigenetic-insights-on-nutrition-hormones-and-eating-behavior/
"Taken together, these data suggest that eating behavior can be the result of an adverse early life environment and can have a life-long influence on neuroendocrine mechanisms. Maternal obesity and diabetes, and overnutrition in early life will end up in a perinatally acquired malprogramming of appetite and satiety pathways and might contribute to the occurrence of hyperphagia, obesity, and hyperinsulinemia throughout later life."
My own little n=1: my mother is obese, maternal grandmother is morbidly obese/T2, maternal grandfather was obese/T2, uncles are overweight or obese/pre-diabetic, and the list goes on and on.
I'm in my 40's and I have a current bmi of 22.8, and I'm the only one in my family who's reversed the progression of pre-diabetes. Back when I was overweight and a pre-diabetic my doctor told me it was most likely genetics, due to my family history of T2, and pretty much told me to accept it. I dropped him as a doctor, lost 50lbs and have had normalized glucose numbers for over 5 years now. Genetics can kiss my tushy
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Epigenetics is the newest iteration of astrology.
None of this data suggests anything more than correlation.
Genetics establishes parameters in adulthood. Behavior and environment is the overwhelming drive prior to this and behavior can push beyond parameters.15 -
I always find it interesting to follow new lines of inquiry - some of them lead down endless rabbit holes that seem to hold promise for contributing to the knowledge base and the rest (probably most) lead to nowhere useful. We'll have to see about epigenetics. But I appreciate the post, Gale, and "inquiring minds wanting to know."2
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GaleHawkins wrote: »https://whatisepigenetics.com/epigenetic-insights-on-nutrition-hormones-and-eating-behavior/
"Taken together, these data suggest that eating behavior can be the result of an adverse early life environment and can have a life-long influence on neuroendocrine mechanisms. Maternal obesity and diabetes, and overnutrition in early life will end up in a perinatally acquired malprogramming of appetite and satiety pathways and might contribute to the occurrence of hyperphagia, obesity, and hyperinsulinemia throughout later life."
My own little n=1: my mother is obese, maternal grandmother is morbidly obese/T2, maternal grandfather was obese/T2, uncles are overweight or obese/pre-diabetic, and the list goes on and on.
I'm in my 40's and I have a current bmi of 22.8, and I'm the only one in my family who's reversed the progression of pre-diabetes. Back when I was overweight and a pre-diabetic my doctor told me it was most likely genetics, due to my family history of T2, and pretty much told me to accept it. I dropped him as a doctor, lost 50lbs and have had normalized glucose numbers for over 5 years now. Genetics can kiss my tushy
@SVZee that is awesome. It's great to hear from research that we are not robots programmed by fixed genetic outcomes. Some of us learned this fact by running our own n=1 studies.
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Interesting article!2
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