Macros

This depends somewhat on your goals, but largely macros are a matter of personal preference (working out what keeps you most satiated, and prioritising that). When it comes to weight loss, calories are king. The default macros are fine to start off with, and I'm sure many people go their entire weight loss without changing them (or even really paying attention to them, so long as they're hitting their calorie goal).

Personally, I think the default protein macro is woefully low, and particularly if you are looking to retain as much muscle as possible whilst losing weight, increasing that one is a good idea. Rather than percentages though, this is ideally a grams goal, based on your lean body mass. To make things simple, aiming for 0.6-0.8g of protein per lb of ideal weight is a good guideline for a minimum protein goal. Next, fats at 0.35(? maybe it's 0.25, someone will correct if I'm wrong, I'm sure!)-0.45g per lb ideal weight minimum, then let carbs fall where they may.