Ozempic for weight loss
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zutshihora
Posts: 30 Member
Started Ozempic 0.25 as suggested by my Dr for weight loss,three weeks ago.
I have been eating carefully,I exercise daily, very regular with food logging but have some 30-35 lbs to lose.
Week1,my appetite dropped,I was carefully eating between 1000-1200 calories.
Week 2,my appetite began to return. Was'nt not hungry any more !! So began to eat.
Week 3 on .25 and feel NO appetite suppression.
Had knocked off close to 2 KGS,but have gained back 1 KG already !
Hoping that the .5 will do the trick. And then the proper dose ,4 weeks after that should definitely do the trick
Have random periods of nausea every day. My IBS seems better. Some gastric issues like mild cramps, some diarrhea ( though with the IBS, it's hard to pin point),some bloating.
Anyone else has a similar experience?
I have been eating carefully,I exercise daily, very regular with food logging but have some 30-35 lbs to lose.
Week1,my appetite dropped,I was carefully eating between 1000-1200 calories.
Week 2,my appetite began to return. Was'nt not hungry any more !! So began to eat.
Week 3 on .25 and feel NO appetite suppression.
Had knocked off close to 2 KGS,but have gained back 1 KG already !
Hoping that the .5 will do the trick. And then the proper dose ,4 weeks after that should definitely do the trick
Have random periods of nausea every day. My IBS seems better. Some gastric issues like mild cramps, some diarrhea ( though with the IBS, it's hard to pin point),some bloating.
Anyone else has a similar experience?
1
Replies
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Appetite is usually a habitual behavior. You lose weight by just eating less. IMO, using a drug to lose weight becomes ineffective because you RELY on it to lose. Once you're off of it, what did you learn?
Change your pattern and AMOUNT of eating and you'll lose weight. Till you change you're behavior, the drug is just a temporary fix.
A.C.E. Certified Personal and Group Fitness Trainer
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Been in fitness for 30 years and have studied kinesiology and nutrition
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Did you try to lose weight before taking the drug? Or was this the first step?
To me, it seems extreme to take a drug for losing a reasonable amount of weight. And I agree with the other poster that a huge part of successful weight loss comes with learning how to eat the right way, not just relying on appetite suppressants.
I would focus on your food intake (weigh everything, and find foods that keep you full and feeling healthy). Unless your doc told you to keep it that low, I'd eat more calories as well.2 -
I agree about the best approach is not to use medication for weight loss.
However just one correction - Ozempic is not an appetite suppressant - it works by filtering more glucose through the kidneys rather than it all being left in the bloodstream to then enter the cells (simplified version)
so weight loss is acheived by the body absorbing less calories.
Ozempic primarily is not a weight loss medication - its primary aim is blood sugar control in diabetics for whom oral meds are not enough - but who don't quite need insulin12 -
In Australia there's actually a shortage of this drugs for use in pre-diabetics, because it's being used so heavily for weight loss purposes, largely thanks to viral Tik-Toks touting it as the latest thing.9
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Yes I can second that. I work in general practice in Australia myself.
It is legal to prescribe as a private script ( ie the patient pays full price, it isn't PBS subsidised) and it is on the PBS ( ie capped subsidised price) for diabetics for whom oral meds are not sufficient or are not tolerated.
There has been a shortage leading to supply issues for those who really need it for medical reasons.5 -
paperpudding wrote: »Yes I can second that. I work in general practice in Australia myself.
It is legal to prescribe as a private script ( ie the patient pays full price, it isn't PBS subsidised) and it is on the PBS ( ie capped subsidised price) for diabetics for whom oral meds are not sufficient or are not tolerated.
There has been a shortage leading to supply issues for those who really need it for medical reasons.
Yup, and private clinics like Juniper are charging $13 a day to prescribe it for weight loss!3 -
I've never taken Ozempic, but if I remember the ads for it, weight loss is fairly minor.... 8-12 lb per year.
Tracking your food intake will probably help you more than any drug. Start off by just tracking every thing you eat.... don't worry about changing what and how you eat. Just get an honest picture of what you are currently doing. I thought I was doing a good job of watching my carb intake but until I started tracking my food ...again... my blood sugar levels and my weight were a constant issue.3 -
So,I am pre diabetic. Have tracked my calories and exercised daily for 6+ years and managed to knock off 12 + KGS My family doctor has suggested this ,seeing all the efforts that I have put in. The last blood work shows an uptick on my A1C,my lipids as well. He thinks ,this could act as a boost,to reset?
I didn't even know that something like this existed..
I was Ok with my weight having plateaued but then it just began to pile back on with nothing having changed as far as my diet and exercise go. I went back to the "obese" category from the "overweight"🤫.2 -
paperpudding wrote: »However just one correction - Ozempic is not an appetite suppressant - it works by filtering more glucose through the kidneys rather than it all being left in the bloodstream to then enter the cells,
so weight loss is acheived by the body absorbing less calories.
Strictly that isn’t correct. Semaglutide is a GLP-1 agonist which works by increasing insulin release, lowering the amount of glucagon released (diabetes) delaying gastric emptying and reducing appetite (weight loss).
It’s a bit like saying Sildenafil (viagra) is not for erectile dysfunction! It is a medication for angina but like the Semaglutide they found it had other applications too.1 -
I started taking Semaglutide Friday last week and I will be on the 0.25ml for another 3 doses. They will be raising it up to the 1g.
I’m on it as I have been struggling with losing and maintaining weight loss since I was 16, nearly 30 years ago now.
I put a lot of weight on (90-115kg, I should be a fit 80-85kg) since covid started as I got a bad dose and then bad long covid which has damaged my lungs. I am verging on being pre diabetic.
I could try exercise alone again but that’s difficult again thanks to long covid as I am exhausted to the point of needing 3x24hrs sleep if I do 30 minutes of very mild exercise.
I’m also unable to work due to the exhaustion. I worked in A&E and would do 4x12hr very intense shifts in a row on my feet for the majority. I’m trying to get back there in the autumn of 2023. Currently it is no way feasible.
I am on the waiting list, and going through the assessment process for a gastric bypass. I’m not looking forward to the eating section of that.
My preference however would have been a abdominoplasty as it’s tough but the stomach is intact. It’s also an overall lower duration (4hrs on the table and a month recovery vs 1-2hrs on the table and 1-2 years recovery and weight loss). I’ve been told that I don’t have a hope of the abdominoplasty (my medical conditions primarily) but yes to the gastric bypass if all the assessments go ok.
In essence, losing the weight and finding a way to keep it off while being able to work and live a normal life is my ultimate goal. If the Semaglutide is the key to this, fantastic!5 -
@Cbionic.
Hang in there Sorry to hear of your struggles. Hope Ozempic works and is enough to do the trick.🤞🤞1 -
Any update?
I used Ozempic at half the starting dose, in October 2021, as I tend to be extremely sensitive to medication side effects.
After 2 weeks, I moved up to the starting dose of 0.25. I used it for about 10 weeks. I was also following a well balanced 1200-1400 cal diet. I was pretty nauseated the first week, then it eased off, then nauseated again when I moved up the dose. What I wasn’t, was hungry. The bugaboo in my weight loss journey over the last decade has been ravenous hunger when I am trying to lose or even maintain my weight. I had been able to lose 52 lbs, from an all time high of 207, back in 2011, though a severely restricted diet of under 1000 cals and extreme workouts of 2-3 hours daily. But by 2021, my weight had crept up, 3 or 4 pounds a year, to almost 200 lbs in 2021, which was affecting my health. I’ve read the studies- the lack of hunger from Ozempic is a central brain effect, not secondary to the nausea.
From October 2021, until December, about 10 weeks, I was comfortably able to lose 18 lbs, down to 182. In late December 2021, I had to start a different medication for a different medical condition, which laid me flat with nausea and vomiting. I stopped the Ozempic at that point in case it was adding to the nausea. It wasn't- it was the other medication. My response to nausea is to usually eat more to settle my stomach, so I usually gain weight as a result of such side effects. But this time I was able to still eat normally and wasn't hungry in response to the n&v. Finally, after 8 weeks of being non functional due to the n&v, my doctor took me off the other med. I never re-started the Ozempic, but was able to eat normally all the last 9 months, and maintain my weight at around 182 until this fall. I have been feeling better, so I decided to try MFP again. (I had failed at MFP in 2015 and 2016, actually gaining weight while eating as directed by MFP and exercising 1-2 hours a day, exhausted all the time). That turned out to be from inability to convert my thyroid medication into the active hormone, so I was actually hypothyroid despite being on meds for it. That took several years and 3 endocrinologists to figure out. In the meantime, I was told that I would be permanently hypothyroid as my metabolism had been damaged by the lack of effective hormone. So I just very carefully watched my diet and tried not to gain weight. But still did. At that point, the Ozempic was a godsend. The sensitization to leptin and other hormones which Ozempic is theorized to do, appears to have been a permanent reset for my body. Now following the MFP program, and exercising very moderately- an hour of walking or gardening a day, I am steadily losing weight. I have dropped from 182 to 172.5 in the last 6 weeks, eating 1300-1400 cals. I am generally not hungry in between meals. I eat about 40% carbs, 35% fat and 25% protein. I dont eat sugar except as fruit or a little maple syrup or honey or homemade jams in small amounts. My goal weight is still 22 lbs away, but it actually looks like I might be able to do it. My goal weight will put me at a BMI of 24.8, technically overweight. But I have also had my body fat percentage done by caliper, and even at my current weight, it is barely over the normal for a woman of my advanced age (over 65).
Ozempic was a game changer for me. I sound like a commercial, but it is a miracle not to be tortured by hunger all my waking and even sleeping hours during the current weight loss journey.9 -
Also, I have received some very negative feedback from people in this community for even mentioning talking to a doctor about the medication option. If you are one of those people, be kind and scroll on. Any criticism of my choice and success simply reveals your ignorance in this area. The misinformation on this thread is enough already.
The weight loss medications have changed in the last 2 years and are saving some people’s lives.
In my country, these medications have been approved for non diabetic weight loss for the last 2 years, and the non -industry-sponsored independant studies are showing results comparable to surgical intervention. They do not work “by filtering glucose”- that is a total misunderstanding of their several neurocentric and metabolic modes of action.
Compared to placebo, people taking Ozempic were able to lose an average of over 30 lbs. that is PROFOUND weight loss, not “modest”.
The meds are not for everyone. They are meant for those in the obese category, BMI over 30, which I was when I tried it. They have some uncomfortable side effects. The recommended dose for weight loss was far too high for me, and it was effective for me at a much lower dose, although I did need to keep increasing the dose every few weeks as I tolerated it. The meds do not work for everyone, the odd person can still gain. And you still have to follow a calorie restricted diet, preferably with some exercise. The meds also reduce cardiovascular disease in those who already have it. They are expensive, even in my country, with some public health funding.
And yeah, I have an MD degree and worked as an expert in nutritional and metabolic diseases for decades, and nothing, with all my knowledge, worked for me until I tried that medication.13 -
They do not work “by filtering glucose”- that is a total misunderstanding of their several neurocentric and metabolic modes of action.
yes they do. In simplified terms, as I stated in my first post
that is how they lower blood sugar level for diabetics. And it is primarily a diabetic medication
I wont appeal to authority of myself, because of course anyone can claim expert status on the internet - a simple google will confirm that.6 -
paperpudding wrote: »They do not work “by filtering glucose”- that is a total misunderstanding of their several neurocentric and metabolic modes of action.
yes they do. In simplified terms, as I stated in my first post
that is how they lower blood sugar level for diabetics. And it is primarily a diabetic medication
I wont appeal to authority of myself, because of course anyone can claim expert status on the internet - a simple google will confirm that.
It's a GLP-1 receptor antagonist.
https://pdf.hres.ca/dpd_pm/00048155.PDF
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neanderthin wrote: »paperpudding wrote: »They do not work “by filtering glucose”- that is a total misunderstanding of their several neurocentric and metabolic modes of action.
yes they do. In simplified terms, as I stated in my first post
that is how they lower blood sugar level for diabetics. And it is primarily a diabetic medication
I wont appeal to authority of myself, because of course anyone can claim expert status on the internet - a simple google will confirm that.
It's a GLP-1 receptor antagonist.
https://pdf.hres.ca/dpd_pm/00048155.PDF
I cannot easily read PDFs on my phone and I am on pain meds. Would you please summarize?
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neanderthin wrote: »paperpudding wrote: »They do not work “by filtering glucose”- that is a total misunderstanding of their several neurocentric and metabolic modes of action.
yes they do. In simplified terms, as I stated in my first post
that is how they lower blood sugar level for diabetics. And it is primarily a diabetic medication
I wont appeal to authority of myself, because of course anyone can claim expert status on the internet - a simple google will confirm that.
It's a GLP-1 receptor antagonist.
https://pdf.hres.ca/dpd_pm/00048155.PDF
Yes it certainly is.
And from the intro in product PDF linked : OZEMPIC® is indicated for the once-weekly treatment of adult patients with type 2 diabetes mellitus to improve glycemic control, in combination with......
59 pages of detailed product info follow.
But clearly primarily for type 2 diabetes; weight loss is a ' side effect'.
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kshama2001 wrote: »neanderthin wrote: »paperpudding wrote: »They do not work “by filtering glucose”- that is a total misunderstanding of their several neurocentric and metabolic modes of action.
yes they do. In simplified terms, as I stated in my first post
that is how they lower blood sugar level for diabetics. And it is primarily a diabetic medication
I wont appeal to authority of myself, because of course anyone can claim expert status on the internet - a simple google will confirm that.
It's a GLP-1 receptor antagonist.
https://pdf.hres.ca/dpd_pm/00048155.PDF
I cannot easily read PDFs on my phone and I am on pain meds. Would you please summarize?
Sure. They're a Glucagon Like Peptide hence the GLP. Basically, they mimic the effect of glucagon which is released in the gut that increases insulin production in the beta cells of the pancreas which help lower blood glucose and they also increase satiety and slows gastric emptying which is the active mechanism for potential weight loss. They also have some effect on blood pressure and cholesterol. Cheers.3 -
Your question has anyone else experienced this on Ozempic. Yes, I have. Almost exactly the same experience. I was not hungry at all the first week. Second week I had some mild symptoms but appetite was back. Third week like I'm not on it at all. I am still being successful in my weight loss, in a large part because I am on the drug for diabetes and I am taking this very seriously. So I am losing slowly, but it mostly has to do with logging and tracking calories and improved commitment to exercise IMO.1
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paperpudding wrote: »They do not work “by filtering glucose”- that is a total misunderstanding of their several neurocentric and metabolic modes of action.
yes they do. In simplified terms, as I stated in my first post
that is how they lower blood sugar level for diabetics. And it is primarily a diabetic medication
I wont appeal to authority of myself, because of course anyone can claim expert status on the internet - a simple google will confirm that.paperpudding wrote: »I agree about the best approach is not to use medication for weight loss.
However just one correction - Ozempic is not an appetite suppressant - it works by filtering more glucose through the kidneys rather than it all being left in the bloodstream to then enter the cells (simplified version)
so weight loss is acheived by the body absorbing less calories.
Ozempic primarily is not a weight loss medication - its primary aim is blood sugar control in diabetics for whom oral meds are not enough - but who don't quite need insulinpaperpudding wrote: »I agree about the best approach is not to use medication for weight loss.
However just one correction - Ozempic is not an appetite suppressant - it works by filtering more glucose through the kidneys rather than it all being left in the bloodstream to then enter the cells (simplified version)
so weight loss is acheived by the body absorbing less calories.
Ozempic primarily is not a weight loss medication - its primary aim is blood sugar control in diabetics for whom oral meds are not enough - but who don't quite need insulin
I suspect your talking about SGLT2 inhibitors? I suspect Ozempic could probably be combined with SGLT2's under a Dr's supervision of course.0
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