When you're going in reverse...

In short, I lost about 35 lbs 4-5 years ago, went to nursing school & maintained my loss but couldn't lose any more. Last year, a year after graduating, job hunting, working 3 jobs, and finally finding one full time job, I started at it again. I was on depo so I had researched and knew it would be difficult on that and that I could gain. I managed to lose about 17 lbs from April to June and was at the lowest I've been, a week after I hit that, the weight just kept coming back on, despite my best efforts. I didn't change my eating habits, I was still working out, just couldn't fight it. I managed to gain and lose the same 5 lbs, then 10 crept on, and I did the same thing. In January of this year the most wonderful relationship I've ever had ended abruptly, a week after that I started a new job which I ended up loathing, and the stress hit me hard. I stopped working out (likely due to the depression I was in) but wasn't eating much (again, the stress) but the weight kept piling on and I gained all of the 17 back plus 10. I didn't get my depo in February hoping that that was somehow to blame for the weight gain, but, alas that hasn't helped, so far. Now, no matter what I do, eat well & workout, I will lose 4 lbs only to gain 8 in a matter of days. It's a never ending battle to get the weight to just stay off for a week. I'm caught in this vicious cycle of not seeing results so not caring anymore. I can't seem to convince myself to just stick it out. Any advice, tips, thoughts, kind or harsh words, good reality check, slap upside the head,etc?