Anyone else out there suffer from MTHFR Defiency?

I have MTHFR and am the owner of MTHFR support on facebook and MTHFRsupport on the web. I work with some of the top researchers in the World. I'm trying to raise awareness on methylenetetrahydrofolate reductase enzyme deficiency. I have many informative lectures and am listing doctors that know about MTHFR and other genetic SNP's (sinfular neucleotide polymorphisms) on the methylation pathway. First I must tell you to make the word folic disappear out of your vocabulary. Folic=bad and folate=good. With MTHFR we have trouble converting folic into folate which is the active methyl donor form needed to convert amino acids such as homocysteine into methionine synthase. Our homocysteine levels should stay in between 6-8 for optimal methylation of toxins. When we have and MTHFR gene mutation, we have trouble keeping adequate levels of glutathione in the body in order to reduce oxidative stress and remove environmental toxins from the body. We cannot take glutathione and obtain optimal results because our methylation cycle is jammed well above glutathione synthase. Many of us with MTHFR, depending on mutations, have trouble with norepinepherin, seratonin, dopamine and epinepherin. The A1298C's have trouble breaking down ammonia in the body because of lack of BH4/tetrahydrobiopterin. These are the examples of what forms of active b vitamins you should be taking. b9 methylfolate/5MTHF/folate as in quatrefolic which I believe is a 4th generation folate. b6 P5P/pyridoxal 5 phosphate and b12 methylcobalamin. Forms that people with MTHFR have trouble converting folic acid, b6 PHCI and b12 cyanocobalamin (yes cyanide phosphate 3'). STAY AWAY from synthetic b vitamins. Dr. Ben Lynch at MTHFR.net can help you out and also I have lectures from some of the top researchers in the World on this subject at MTHFRsupport.com. Things that are quite common with MTHFR: Spina bifida, neural tube defects, autism, Down Syndrome, repeated miscarriage, still born, autism, just to name a few. Which can all be avoided by knowing your MTHFR status, finding a doctor who knows about the subject (I look for doctors daily for people), becoming proactive now that you know the root cause, avoiding vitamins and foods fortified with synthetic b vitamins and getting the most out of and organic diet and active methyl donor b vitamins. Being cautious about childhood vaccinations on your children since thimerasol (mercury), formaldahyde and aluminum to name a few of the preservatives, deplete glutathione that we are already lacking and cause brain damage during brain developmentation. This is just a short version of what is needed to know. There are tons of active b vitamins to put in your system. Please contact me or doctor Ben Lynch if you would like to know anymore.

I read that as motherf****r deficiency.

Carry on.

Hi must_deflate.

Glad you've found out about it - it's going to be very much in your favour from now on.

Yes, I am compound heterozygous like you, and I've been supplementing for about a year now. I experienced a great improvement at the beginning, which then levelled out. It turns out I was taking the wrong form of methyl-B12, so now I'm on the better version (for me) I'm feeling great. The way I found out this was by running my genome through an online company, that looks at all of the relevant mutations (there are quite a few that influence the two you mentioned) but that was only possible because I'd had my whole genome analysed through 23andme. Are you in a position to do that? If so, pm me and I'll let you know which company I used.