Amazing new findings about ED - could be curable with....antibiotics!

I am SO EXCITED to read this recent discovery...A kind of bacteria that can live in the stomach could potentially be the cause for eating disorders and could be curable with antibiotics, saving who knows how many people from years and years of psychological torture! Of course you never want to dismiss mental health issues that arise from eating disorders, but to think we could treat it so simply would be incredible!

I just wanted to share the article so others may find as much hope in it as I did!

(Just for clarification, I do not have an ED, but I watched a close friend come very very close to starving to death from anorexia)
[url=" https://www.sciencenews.org/blog/science-ticker/gut-bacteria-protein-linked-anorexia-and-bulimiahttp://"]Article Here![/url]
«13

Replies

  • weightliftingdiva
    weightliftingdiva Posts: 522 Member
    Interesting. I wonder what the results would be if you tested the gut bacteria of people with ED and compared it to the bacteria of those who don't have an ED. Of course, that would be correlational, and not causal. Interesting stuff nonetheless, especially because I've learned the most about psychosocial factors influencing ED and not biological ones.
  • SpockAdventures
    SpockAdventures Posts: 103 Member
    Well this is all new research. They have compared it to those without ED, and this is a bacteria they have found that is exclusive to people with eating disorders. It sends a signal to the brain that the stomach is full, so it makes it very difficult for people to eat because they feel or think they are full when they aren't. This, of course, would have varying mental health effects on people.
  • mamafazz
    mamafazz Posts: 92 Member
    I'm a nurse and when I saw ED the 1st thing I thought was erectile dysfunction? LOL
  • lishie_rebooted
    lishie_rebooted Posts: 2,973 Member
    The article you linked doesn't give a lot of info about the study plus it was tested in mice not humans. At least it does link to the actual study but you can only read the abstract.

    I wouldn't call it amazing just yet
  • SpockAdventures
    SpockAdventures Posts: 103 Member
    hahahah That's awesome. What a mix up that would be!
  • conniedj
    conniedj Posts: 470 Member
    while gut bacteria is important for everyone...It definitely does not say it causes--but contributes, and it is only hypothesis. Eating disorders are primarily psychological...and should be treated as such. It is well known that the brain chemistry in those suffering from ED is altered in what is called the "reward" center of the brain.

    But with that said, the food that normal folks eat these days is greatly lacking in pre- and probiotics. More good gut bacteria is good for everyone!
  • SpockAdventures
    SpockAdventures Posts: 103 Member
    We've always believed them to be psychological - what this study is saying is that, that may not be the case. Of course this is preliminary studies, but they have shown in mice and are ready to move to human trials, that this particular gut bacteria (which not everyone has), can be treated with antibiotics and the eating disorder is treated.
  • weightliftingdiva
    weightliftingdiva Posts: 522 Member
    Well this is all new research. They have compared it to those without ED, and this is a bacteria they have found that is exclusive to people with eating disorders. It sends a signal to the brain that the stomach is full, so it makes it very difficult for people to eat because they feel or think they are full when they aren't. This, of course, would have varying mental health effects on people.

    Are you talking about the study you presented? That study was done with mice, not people. That's why I brought up doing something comparable (yet ethical) with people.
  • SpockAdventures
    SpockAdventures Posts: 103 Member
    Yes, that is what I said to another commenter - all scientific research is done on mice or pigs or chimps before they can start testing the theory on humans. They are moving on to human trials, next, it's just that the research is very promising. I never said that this was absolutely true, just that there is the possibility that there could be a primary physiological reason for most ED and the mental health issues and changes in brain chemistry could potentially be side effects of having a stomach that essentially wants to starve itself. It would just be a HUGE step in fighting eating disorders.
  • dakotababy
    dakotababy Posts: 2,406 Member
    I believe eating disorders begin with mental health, skewed perceptions and unrealistic goals. THEN perhaps the gut begins to show signs of the disorder. I think this could help, but not a cure in of its self.

    Thats like saying there is a cure for addiction without any psychological help, but just some meds.
  • SpockAdventures
    SpockAdventures Posts: 103 Member
    No no, it's saying that the mental health stuff could be the result of your body starving itself. Of course mental health plays a part - but how amazing would it be if you could take huge strides in reintroducing food to someone if you can eliminate a physiological component??

    I guess I just find this incredibly hopeful and wonderful. The implications on being able to treat the desire not to have food, so the mental health side can be focused and treated more directly without having to be mixed in with trying to reteach someone's stomach to want food again. Maybe it's just me, but like I said, I think it's incredibly fascinating and exciting!
  • laurajo521
    laurajo521 Posts: 91 Member
    First of all, I thought erectile dysfunction too at first. LOL

    This is my theory on this based on the limited info that I have read here. I think that eating disorders are mostly psychological. What I think is that this bacteria in the stomach might be what gives someone with the psychology the "willpower" to do it. I know a girl who has the most messed-up views on body image and food that I have ever seen, and it constantly amazes me that she doesn't have an eating disorder. I know that is bad to say, but it really does. I always say if she had the willpower to do it, she would have starved herself years ago. But maybe it's not willpower; maybe it's a bacteria that makes you feel full. OR maybe the bacteria is caused as a byproduct of starving yourself for so long.

    It's all interesting to think about, and it is exciting that scientists are trying to figure what's behind eating disorders. However, I am sitting here with an Overeaters Anonymous meditation book on my desk, knowing full well that if you have the addiction/compulsion genes and something clicks in your brain, you're probably headed to a life of disordered eating.
  • SpockAdventures
    SpockAdventures Posts: 103 Member
    OH I agree wholeheartedly - I definitely KNOW that there are mental health implications, whether they are the result of a body that is starving itself or is something that one is more susceptible to and is fueled by an, essentially, bacterial infection. Those things can be addressed so much more efficiently if you don't also have to relearn how to enjoy food, or be accepting of. You can focus on the body image issues, the anxiety, the depression, anger, etc. that accompanies eating disorders directly.
  • Maitria
    Maitria Posts: 439 Member
    No no, it's saying that the mental health stuff could be the result of your body starving itself. Of course mental health plays a part - but how amazing would it be if you could take huge strides in reintroducing food to someone if you can eliminate a physiological component??

    I guess I just find this incredibly hopeful and wonderful. The implications on being able to treat the desire not to have food, so the mental health side can be focused and treated more directly without having to be mixed in with trying to reteach someone's stomach to want food again. Maybe it's just me, but like I said, I think it's incredibly fascinating and exciting!

    Many people with eating disorders feel hungry; it's the intense fear of getting fat that prevents them from eating. People with bulimia can eat quite a bit; it's factors like shame, guilt, anxiety of weight gain, and disgust that often lead to purges. (I'm generalizing, for sure, there are of course other unique to the individual reasons for psychological distress leading to physical symptoms.)



  • SpockAdventures
    SpockAdventures Posts: 103 Member
    I never said you don't feel hungry - the gut bacteria just can make your brain find food unappealing which can turn you off of food.

    I speak to this not just having a friend that nearly died of anorexia, but my husband has a very very similar illness that causes similar symptoms in which he knows he should be hungry, and sometimes he actually feels he is. But as soon as he sees or smells food, the fuller his stomach begins to feel, so eating a meal feels to him, like he's trying to have a full meal on top of an already full stomach. The food triggers the bacteria to send signals to the brain saying he is full, so the longer he is around food or smells it, the fuller he feels and the less appealing the food is. He has studied this extensively because, you know, he doesn't want to starve to death, and because of a very high IQ and mental health issues he lives with, he has to have a very clear idea of how to maintain his health.

    So, while they are not exactly the same, what my husband lives with is very similar to the effects of this new bacteria they found.
  • Maitria
    Maitria Posts: 439 Member
    I never said you don't feel hungry - the gut bacteria just can make your brain find food unappealing which can turn you off of food.

    I speak to this not just having a friend that nearly died of anorexia, but my husband has a very very similar illness that causes similar symptoms in which he knows he should be hungry, and sometimes he actually feels he is. But as soon as he sees or smells food, the fuller his stomach begins to feel, so eating a meal feels to him, like he's trying to have a full meal on top of an already full stomach. The food triggers the bacteria to send signals to the brain saying he is full, so the longer he is around food or smells it, the fuller he feels and the less appealing the food is. He has studied this extensively because, you know, he doesn't want to starve to death, and because of a very high IQ and mental health issues he lives with, he has to have a very clear idea of how to maintain his health.

    So, while they are not exactly the same, what my husband lives with is very similar to the effects of this new bacteria they found.

    I would argue that this condition is it's own separate condition. You could call it an eating disorder, sure, but the "traditional" eating disorders are very unlikely to be caused by what you describe. Many people with eating disorders are often somewhat obsessed with food and many have safe foods. I can get that "I know I should be hungry but I feel nauseated by the idea of food" sensation from time to time, but that is entirely different from a distorted view of self and a delusional fear of getting fat. (Success with anti-psychotics has been demonstrated for some, not all, people with the traditional eating disorders.)

    Your husband would possibly benefit quite a bit from this antibiotic, and that is exciting for him. What you describe still doesn't meet criteria for anorexia nervosa or bulimia.

  • SpockAdventures
    SpockAdventures Posts: 103 Member
    I know they aren't the same, I said they are very similiar. The bacteria of each condition are cousins of one another. I will say again, I know that there are heavy psychological issues with eating disorders, but scientists who know a lot more than I do because I'm not a scientist, say that they may have found a very real physiological component to eating disorders. I don't mean to come across as condescending - understand it's a little frustrating for everyone to tell me I'm wrong about there being a physical reason for something, when I'm not the one making the argument. I'm sharing the findings of scientific studies, which whether you choose to believe them or not, are scientific facts that they are discovering and are admittedly not proven on humans yet.
  • Maitria
    Maitria Posts: 439 Member
    I know they aren't the same, I said they are very similiar. The bacteria of each condition are cousins of one another. I will say again, I know that there are heavy psychological issues with eating disorders, but scientists who know a lot more than I do because I'm not a scientist, say that they may have found a very real physiological component to eating disorders. I don't mean to come across as condescending - understand it's a little frustrating for everyone to tell me I'm wrong about there being a physical reason for something, when I'm not the one making the argument. I'm sharing the findings of scientific studies, which whether you choose to believe them or not, are scientific facts that they are discovering and are admittedly not proven on humans yet.

    I understand why you are frustrated, but when you post a topic about extremely complex conditions and state that they could be as simple as a need for antibiotics, you're going to get criticism of that argument. These particular scientists having an idea do not outweigh the years of research already done.

    My first question is, if eating disorders are primarily physiological, from gut bacteria, how do people recover with therapy? My second question is, how do they know this gut bacteria is the cause and not caused by the eating disorder? I could not read the article, maybe this is addressed.

    Anorexia nervosa has the highest fatality rate of any mental illness. It's exciting to think that an antibiotic could be the cure of all of this, but there is a lot of reason to be suspicious and challenge those findings.

  • Maitria
    Maitria Posts: 439 Member
    About me believing the scientific facts: you haven't really established the importance of these facts yet. This comes back to the causation versus correlation argument. It's easy for me to believe that people with ED have different gut bacteria than those who do not. That's an unsurprising outcome in people who have disordered feeding habits.
  • SpockAdventures
    SpockAdventures Posts: 103 Member
    I can understand where you are coming from as well. I think it's that while I am a skeptical person generally, when there are breakthroughs in science like this that could have amazing future implications, I tend to see it in a very exciting hopeful light and leave the skepticism to the scientists that now have to work to prove that this could make HUGE differences in the lives of so many.

    And as far as getting better with therapy - I do think that there are probably plenty of cases of eating disorders that aren't affected by a gut bacteria, definitely. We could just be looking at a study in which we find even a portion of those diagnosed could be essentially cured with little to no therapy if their mental health issues don't run too deep.

    I should also clarify that I do understand mental health issues - I am bipolar and have terrible generalized anxiety disorder, so much so that I am on disability for these things, so I don't take mental health lightly. If there were a study that showed something similar for either of my conditions, I'd be equally as excited and hopeful - my "religion" is science. I don't believe in god, I trust and believe in scientists, so that could very well be the difference in the weight I place on studies like this over others, as well.

    And I know that the topic and ideas behind the study are controversial and that there will be some skepticism. I would prefer to just direct the conversation to question the study and not me, who is just sharing said study. :wink: