This topic is an expansion of what is being discussed with regard to the Biggest Loser, "that the brain’s weight-regulation system considers your set point to be the correct weight for you, whether or not your doctor agrees"
. (Click link to see the article where I pulled that quote).
The NPR radio show "Forum"
had a good discussion on the topic today.
What I take from the conversation is that once you have allowed yourself to become overweight or obese, you have already done some damage. New fat cells can be created as you gain weight, but they do not disappear when you lose. Hormones play a large role in hunger signals to help us gain back weight, metabolism slows down, etc.
I like to see results on the scale, but I don't think of myself as being on a diet. And frankly, results on the scale are extremely slow, and sometimes all I can do is maintain. But I have a feeling getting to and staying at my goal weight comfortably may not happen.