METFORMIN

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Replies

  • hookilau
    hookilau Posts: 3,134 Member
    This article from NIH gives the straight skinny on metformin and the liver. http://livertox.nlm.nih.gov/Metformin.htm

    Thanks for the link :drinker:
    It's always good to keep up to speed on meds and possible side effects etc. I'm on the XR and so far, so good.
    Clearly we all have different issues and this makes certain things a little complicated. :wink:

    All the best.
  • SharonNehring
    SharonNehring Posts: 535 Member
    It's been fabulous for me. It greatly decreases my appetite and cravings, along with lowering my blood sugars. It's best to eat a reduced carb diet for PCOS and IR. I'm not saying no carb, but rescued carb in the 100-125gm range or so. Daily exercise is very important as well, as it helps your body with glucose metabolism.
  • earlnabby
    earlnabby Posts: 8,171 Member
    I took metformin for just over 3 weeks and my EGFR dropped from 59 to 34 in that short time. My doctor prescribed glipzide instead and my EGFR is back over 60. She also thinks I may be able to get off meds entirely in the next 6 months as long as I continue with the lifestyle changes. WooHoo!
  • CherrypieOmy
    CherrypieOmy Posts: 20
    I was given this for PCOS myself as the doctors said that it restored periods for some people. I took it for about ten years and stopped taking it last year because I started getting acne pretty badly (Dr thought it was the metformin causing it.)

    It did help for the first year in aiding the management of the insulin resistance, but as far as periods, it did nothing for me. I had more periods after taking Zoloft than I did metformin. (I realise they are two different drugs for two very different things.)

    Blood tests show that without the metformin my blood sugar was still pretty good. I manage it by keeping carbs and processed sugar within normal to low levels. 175g or less per day. There was very little deviation from the levels while on it.

    As it turns out the acne might be a reaction to some blood pressure medication as I'm allergic to some of the ingredients and didn't realise that they belonged to the same class of drugs. Go figure. Further to this, I've had a lot of aches and pains plus dehydration recently despite drinking like a horse. If you have blood pressure problems in addition to the insulin resistance, keep a look out for how you feel while taking them.

    Beta blockers and ace inhibitors may cause a very slow weight loss and a lot of frustration from possible water retention that will hide the fact you are losing weight.

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