Thumb Pain from Lifting?

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Any suggestions or info on serious pain in thumbs and palms from lifting? My right thumb is terrible for past 4 or 5 days. Hurts to pick things up or squeeze with it. I'm assuming it's related to lifting. Anybody have similar problems and have some suggestions on improving it? I can't lift last few days because the pain is so bad. Heck, it hurts to type!