Artificial Sweeteners
AllisonConnell1301
Posts: 98
There is a lot of talk about artificial sweeteners and the damage they can cause your body.
What do you all believe?
Do you try to avoid them? Do you eat them? Have you noticed any affects?
What do you all believe?
Do you try to avoid them? Do you eat them? Have you noticed any affects?
0
Replies
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A lot of them can be bad for you, especially the ones in soda. I do not mind Splenda because your body cannot absorb it. It just passes right through with no damage. I know this because not only have I used it for years and faced no consequences, but also because I took several nutrition classes while in college; almost every textbook and professor said the same thing. But def do your own research. There are several good arguments for and against sweeteners. I do believe there are some that are way better than others.0
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i dont eat any fake sugar
Trying to keep your weight down and trying to be healthy can be totally different things. There was a time in my life when I believed that sugar-free foods and drinks were actually good for me. I was drinking sugar-free Red Bulls and dumping Splenda into my morning coffee like my life depended on it. I'm a little embarrassed to admit that I considered myself healthy then.
I always heard negative things about artificial sweeteners in passing, but dodged conversations about it and pretended like I didn't hear or read anything knocking the merit of the products. What can I say? I was addicted to caffeine and totally uninterested in ditching my habit. (And who doesn't love a low-calorie caffeine fix?)
But after learning a thing or two about artificial sweeteners, I've left my sugar-free energy drink toting days behind me.
Some facts about artificial sweeteners that made me change my mind:
1. They are chemicals or natural compounds that replace the sweetness of sugar, without all of the calories. But sometimes the label 'sugar-free' masks calories present in the food or drink. Of course you can always read the product's label, but believe it or not, there are a whole lot of people out there who think that sugar-free or fat-free means low-calorie. On top of that, there are some recent studies that have shown that artificial sweeteners can actually increase your appetite. And then there are sugar-free products with ingredients that can raise your blood sugar dramatically—like the white flour in sugar-free cookies. All in all, 'sugar-free' doesn't always mean 'diet-friendly'.
2. Aspartame (NutraSweet, Equal, NatraSweet, Canderel, Spoonfuls, DiabetiSweet) is a common chemical sweetener with possible side effects that sound like they're out of a horror movie. From hallucinations to seizures to brain tumors, it is hardly worth consuming for the sake of saved calories.
3. Sucralose (Otherwise known as Splenda, my past-sweetener of choice), is scary. Recent research suggests that Splenda can enlarge both the liver and kidneys and shrink the thymus glands. Sucralose breaks down into small amounts of dichlorofructose, which has not been tested adequately tested in humans. Splenda reportedly can cause skin rashes, panic, diarrhea, headaches, bladder issues, stomach pain, and those side effects don't even sum it up.
Think this sounds bad? Do some further research. Most artificial sweeteners on store shelves are accompanied by numerous side-effect stories. (Some recent studies suggest they cause cancer. Should something as serious as cancer really be overlooked?) Research also suggests that they actually cause overeating among consumers.
In addition to all of this, consider the waste involved in the industry of artificially sweetening. Ever stepped into a coffee shop and noticed a mound of sugar substitute packets building on the counter or in the trash? We've been wasting one of our most precious resources for the sake of a sweetener that can harm our bodies and prevent weight loss. It sounds unfathomable, but true nonetheless.
What you can do instead to get your sugar fix:
Turn to natural sweeteners for your drinks and food alike. Honey, organic maple syrup, molasses, date sugar, brown rice syrup, and stevia are just a few natural sweeteners you can turn to. Not only will they wreak less havoc on your body, but your support of these sweeteners instead will, eventually, help to slow the production of toxic artificial sweeteners--which are significantly less delicious in my opinion anyway.
x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x0 -
I was formerly an aspartame junkie- however, I was a teenager and hadn't bothered to educate myself about the contents of what I was ingesting. All I knew was that it didn't have calories, which was apparently good. I never really stopped to think about why I was getting nasty headaches after all those Sugar-Free Red Bulls and diet tea drinks. I moved onto Splenda after hearing some terrible things about aspartame, which lessened my headaches, but I always felt a little ill after consuming something with it.
I try to avoid artificial sweeteners entirely now, and just use honey or Stevia. Alternatively, I'll just take the bullet and if I've convinced myself that I MUST have a soda, I'll drink an all-natural one and bite the sugar bullet instead of a diet.0 -
They're fine. I use them every day.0
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i dont eat any fake sugar
Trying to keep your weight down and trying to be healthy can be totally different things. There was a time in my life when I believed that sugar-free foods and drinks were actually good for me. I was drinking sugar-free Red Bulls and dumping Splenda into my morning coffee like my life depended on it. I'm a little embarrassed to admit that I considered myself healthy then.
I always heard negative things about artificial sweeteners in passing, but dodged conversations about it and pretended like I didn't hear or read anything knocking the merit of the products. What can I say? I was addicted to caffeine and totally uninterested in ditching my habit. (And who doesn't love a low-calorie caffeine fix?)
But after learning a thing or two about artificial sweeteners, I've left my sugar-free energy drink toting days behind me.
Some facts about artificial sweeteners that made me change my mind:
1. They are chemicals or natural compounds that replace the sweetness of sugar, without all of the calories. But sometimes the label 'sugar-free' masks calories present in the food or drink. Of course you can always read the product's label, but believe it or not, there are a whole lot of people out there who think that sugar-free or fat-free means low-calorie. On top of that, there are some recent studies that have shown that artificial sweeteners can actually increase your appetite. And then there are sugar-free products with ingredients that can raise your blood sugar dramatically—like the white flour in sugar-free cookies. All in all, 'sugar-free' doesn't always mean 'diet-friendly'.
2. Aspartame (NutraSweet, Equal, NatraSweet, Canderel, Spoonfuls, DiabetiSweet) is a common chemical sweetener with possible side effects that sound like they're out of a horror movie. From hallucinations to seizures to brain tumors, it is hardly worth consuming for the sake of saved calories.
3. Sucralose (Otherwise known as Splenda, my past-sweetener of choice), is scary. Recent research suggests that Splenda can enlarge both the liver and kidneys and shrink the thymus glands. Sucralose breaks down into small amounts of dichlorofructose, which has not been tested adequately tested in humans. Splenda reportedly can cause skin rashes, panic, diarrhea, headaches, bladder issues, stomach pain, and those side effects don't even sum it up.
Think this sounds bad? Do some further research. Most artificial sweeteners on store shelves are accompanied by numerous side-effect stories. (Some recent studies suggest they cause cancer. Should something as serious as cancer really be overlooked?) Research also suggests that they actually cause overeating among consumers.
In addition to all of this, consider the waste involved in the industry of artificially sweetening. Ever stepped into a coffee shop and noticed a mound of sugar substitute packets building on the counter or in the trash? We've been wasting one of our most precious resources for the sake of a sweetener that can harm our bodies and prevent weight loss. It sounds unfathomable, but true nonetheless.
What you can do instead to get your sugar fix:
Turn to natural sweeteners for your drinks and food alike. Honey, organic maple syrup, molasses, date sugar, brown rice syrup, and stevia are just a few natural sweeteners you can turn to. Not only will they wreak less havoc on your body, but your support of these sweeteners instead will, eventually, help to slow the production of toxic artificial sweeteners--which are significantly less delicious in my opinion anyway.
x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
I totally agree! I have watched documentaries re: people who worked in factories that made aspartame and some of the workers were riddled with tumors and various types of cancer. it was very eye opening. I use stevia, agave, molasses, coconut sugar, and honey.0 -
1. They are chemicals or natural compounds that replace the sweetness of sugar, without all of the calories. But sometimes the label 'sugar-free' masks calories present in the food or drink. Of course you can always read the product's label, but believe it or not, there are a whole lot of people out there who think that sugar-free or fat-free means low-calorie. On top of that, there are some recent studies that have shown that artificial sweeteners can actually increase your appetite. And then there are sugar-free products with ingredients that can raise your blood sugar dramatically—like the white flour in sugar-free cookies. All in all, 'sugar-free' doesn't always mean 'diet-friendly'.
2. Aspartame (NutraSweet, Equal, NatraSweet, Canderel, Spoonfuls, DiabetiSweet) is a common chemical sweetener with possible side effects that sound like they're out of a horror movie. From hallucinations to seizures to brain tumors, it is hardly worth consuming for the sake of saved calories.
3. Sucralose (Otherwise known as Splenda, my past-sweetener of choice), is scary. Recent research suggests that Splenda can enlarge both the liver and kidneys and shrink the thymus glands. Sucralose breaks down into small amounts of dichlorofructose, which has not been tested adequately tested in humans. Splenda reportedly can cause skin rashes, panic, diarrhea, headaches, bladder issues, stomach pain, and those side effects don't even sum it up.
Think this sounds bad? Do some further research. Most artificial sweeteners on store shelves are accompanied by numerous side-effect stories. (Some recent studies suggest they cause cancer. Should something as serious as cancer really be overlooked?) Research also suggests that they actually cause overeating among consumers.
Utter nonsense with no basis in fact.0 -
I had a horrible reaction to Splenda years ago and I will no longer touch the stuff. It is chlorinated sugar and the reason your body doesn't metabolize it is that your body has no idea what it is. As a result, it takes three days for your body to get the substance out of your system. Therefore, if you are consuming it every day, you are building it up in your system. When this happen, some people will have a reaction-- some get very bad rashes or violent digestion problems. For me, I was having such terrible cramps that I thought I had ruptured something internally! I was able to figure out that my daily ingestion of Splenda in my iced skim latte was the culprit. After about a week of abstaining, all my lower GI issues went away. I'll never touch the stuff again.0
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I mostly use good old fashioned saccharine (NectaSweet tablets) and have for YEARS. (Psssst - using saccharine in your tea with a piece of pie doesn't make the pie diet food!) I am 64. My mom and dad used it several times a day their whole lives. She lived to 92 and he to 97, healthy to the end. I am using a bit of stevia now also and I use Sweet and Low or Equal or Spenda when I go out. Now IF I had an allergic reaction to it, of course I wouldn't use it. But just because SOME people are allergic to peanuts, doesn't mean NO ONE should ever eat peanuts.0
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If you take those kind of artificial of any kind, there always be a side effect. That's why it's artificial.0
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Artificial sweeteners have unfair rep. They are blamed by overweight people for their weight gain or lack of weight loss. The fact is, people need to be accountable for what they put into their mouth in terms of overall nutrition, not whether they've taken a packet of sweetener. If you want to put some in your tea or coffee or oats, then there is absolutely nothing wrong with doing so. You won't get sick, you won't get cancer and you certainly won't get fat.
That said, I would not recommend diet sodas in place of plain water. But if you want to drink one, then go for it. Just don't go consuming 20+ cans a day. Some people do claim to have headaches when taking aspartame, but I don't know if there is any data to suggest that there is a causal link between consuming aspartame and experiencing headaches.
Aspartame Not Linked to Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797853/
- Saccharin
...there is no clear evidence that saccharin causes cancer in humans, saccharin was delisted in 2000 from the U.S. National Toxicology Program’s Report on Carcinogens...
- Aspartame
...Subsequently, NCI examined human data from the NIH-AARP Diet and Health Study of over half a million retirees. Increasing consumption of aspartame-containing beverages was not associated with the development of lymphoma, leukemia, or brain cancer (2).
- Acesulfame potassium, Sucralose, and Neotame
...Before approving these sweeteners, the FDA reviewed more than 100 safety studies that were conducted on each sweetener, including studies to assess cancer risk. The results of these studies showed no evidence that these sweeteners cause cancer or pose any other threat to human health.
http://www.cancer.gov/cancertopics/factsheet/Risk/artificial-sweeteners
Does aspartame cause cancer?
...But studies in people can sometimes be hard to interpret, because there may be other factors affecting the results that are hard to account for.
http://www.cancer.org/cancer/cancercauses/othercarcinogens/athome/aspartame0 -
0
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*sips diet coke*
they are fine.0 -
Artificial sweeteners have unfair rep. They are blamed by overweight people for their weight gain or lack of weight loss. The fact is, people need to be accountable for what they put into their mouth in terms of overall nutrition, not whether they've taken a packet of sweetener. If you want to put some in your tea or coffee or oats, then there is absolutely nothing wrong with doing so. You won't get sick, you won't get cancer and you certainly won't get fat.
That said, I would not recommend diet sodas in place of plain water. But if you want to drink one, then go for it. Just don't go consuming 20+ cans a day. Some people do claim to have headaches when taking aspartame, but I don't know if there is any data to suggest that there is a causal link between consuming aspartame and experiencing headaches.
Aspartame Not Linked to Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797853/
- Saccharin
...there is no clear evidence that saccharin causes cancer in humans, saccharin was delisted in 2000 from the U.S. National Toxicology Program’s Report on Carcinogens...
- Aspartame
...Subsequently, NCI examined human data from the NIH-AARP Diet and Health Study of over half a million retirees. Increasing consumption of aspartame-containing beverages was not associated with the development of lymphoma, leukemia, or brain cancer (2).
- Acesulfame potassium, Sucralose, and Neotame
...Before approving these sweeteners, the FDA reviewed more than 100 safety studies that were conducted on each sweetener, including studies to assess cancer risk. The results of these studies showed no evidence that these sweeteners cause cancer or pose any other threat to human health.
http://www.cancer.gov/cancertopics/factsheet/Risk/artificial-sweeteners
Does aspartame cause cancer?
...But studies in people can sometimes be hard to interpret, because there may be other factors affecting the results that are hard to account for.
http://www.cancer.org/cancer/cancercauses/othercarcinogens/athome/aspartame
...but in 2008, 2012 and 2013 :Studies on the effects of aspartame on memory and oxidative stress in brain of mice.
Abdel-Salam OM, Salem NA, El-Shamarka ME, Hussein JS, Ahmed NA, El-Nagar ME.
Conclusions : These findings suggest impaired memory performance and increased brain oxidative stress by repeated aspartame administration. The impaired memory performance is likely to involve increased oxidative stress as well as decreased brain glucose availability.
In 2008 :Direct and indirect cellular effects of aspartame on the brain
P Humphries1,2 , E Pretorius1 and H Naude´ 1
Conclusion
It was seen that aspartame disturbs amino acid metabolism, protein structure and metabolism, integrity of nucleic acids,
neuronal function, endocrine balances and changes in the brain concentrations of catecholamines. It was also reported
that aspartame and its breakdown products cause nerves to fire excessively, which indirectly causes a very high rate of
neuron depolarization. The energy systems for certain required enzyme reactions become compromised, thus indirectly leading to the inability of enzymes to function optimally. TheATP stores in the cells are depleted, indicating that low concentrations of glucose are present in the cells, and this in turn will indirectly decrease the synthesis of acetylcholine, glutamate and GABA. The intracellular calcium uptake has been altered, thus the functioning of glutamate as an excitatory neurotransmitter is inhibited.
Mitochondria are damaged, which could lead to apoptosis of cells and infertility in men and also a lowered rate of oxidative metabolism are present, thus lowering concentrations ofthe transmitters glutamate and production of GABA.
The cellular walls are destroyed;thus,the cells (endothelium of the capillaries) are more permeable, leading to a compromised BBB. Thus, overall oxidative stress and neurodegeneration are present. From all the adverse effects caused by this product, it is
suggested that serious further testing and research be undertaken to eliminate any and all controversies surrounding this product.
In 2013 :Effects of aspartame metabolites on astrocytes and neurons.
Karol Rycerz, Jadwiga Elżbieta Jaworska-Adamu
Conclusions
This article analyses the direct and indirect role of astrocytes participating in the toxic effects of metabo- lites of aspartame. These glial cells modulate BBB by functional changes in endothelial neutral amino acid transporters. As a result of consuming aspartame, phenylalanine shows a significant affinity for the NAAT transporters in the BBB blocking access for the essen- tial amino acids necessary to the synthesis of dopa- mine and serotonin in the CNS. Astrocytes may play an indirect role in this process.
Aspartate present in excess as a metabolite of aspartame is neurotoxic and it is a substrate for glu- tamate. This amino acid acting on neuronal mGluR receptors and NMDA receptors leads to hyperexcita- bility of cells, free radicals release, oxidative stress and neuronal degeneration. Initially astrocytes are the pro- tectors of neurons and later, with an excess of gluta-
Folia Neuropathologica 2013; 51/1
15
Karol Rycerz, Jadwiga Elżbieta Jaworska-Adamu
mate in the extracellular space, they are activated and release toxic substances intensifying neurodegener- ation.
The methanol, contained in aspartame, is insuffi- cient to bring about alterations in the CNS.
Astrocytes are the source of cancers such as astro- cytoma caused by the carcinogenic effect of diketo- piperazine.
Further research of aspartame’s impact on the mor- phology and function of astrocytes and neurons is nec- essary to be carried out.
Don't you think it's a little odd for a sweetener that has been synthesized in 1965 that there is so much controversy ? Not to mention the FDA is the first one to claim it's non-toxicity, but at the very same time states about Stevia :FDA has not permitted the use of whole-leaf Stevia or crude Stevia extracts because these substances have not been approved for use as a food additive. FDA does not consider their use in food to be GRAS in light of reports in the literature that raise concerns about the use of these substances
Edit : a bit of history regarding Aspartame approval :It is no coincidence that the FDA Chairman who stood in the way of aspartame's approval was removed from office the day Ronald Reagan took office. His replacement (Dr. Arthur Hill Hayes) was in part planted there by Donald Rumsfeld, CEO of G.D. Searle (aspartame is produced by G.D. Searle Company), in order to allegedly get a friendly rubber stamp on aspartame's approval.
But even with a friendly new FDA Chairman in place, the agency still rejected aspartame for approval by a 3-2 margin. What reprehensible, bordering on criminal action did Chairman Hayes do next? He added a sixth member to the approval board, who voted in favor of aspartame. Then, with a 3-3 tie on the issue, Chairman Hayes himself broke the deadlock with his own vote of approval for aspartame.
So he packed the board and then used his own vote as a tie-breaker. All apparently perfectly legal ...
And one of Hayes' last acts in office before he left the FDA in1983 amid accusations that he was accepting corporate gifts for political favors, was to approve aspartame for use in beverages. Does this sound to you like a man-made synthetic chemical that should have never been allowed into the world's food supply?0 -
Artificial sweeteners have unfair rep. They are blamed by overweight people for their weight gain or lack of weight loss. The fact is, people need to be accountable for what they put into their mouth in terms of overall nutrition, not whether they've taken a packet of sweetener. If you want to put some in your tea or coffee or oats, then there is absolutely nothing wrong with doing so. You won't get sick, you won't get cancer and you certainly won't get fat.
That said, I would not recommend diet sodas in place of plain water. But if you want to drink one, then go for it. Just don't go consuming 20+ cans a day. Some people do claim to have headaches when taking aspartame, but I don't know if there is any data to suggest that there is a causal link between consuming aspartame and experiencing headaches.
Aspartame Not Linked to Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797853/
- Saccharin
...there is no clear evidence that saccharin causes cancer in humans, saccharin was delisted in 2000 from the U.S. National Toxicology Program’s Report on Carcinogens...
- Aspartame
...Subsequently, NCI examined human data from the NIH-AARP Diet and Health Study of over half a million retirees. Increasing consumption of aspartame-containing beverages was not associated with the development of lymphoma, leukemia, or brain cancer (2).
- Acesulfame potassium, Sucralose, and Neotame
...Before approving these sweeteners, the FDA reviewed more than 100 safety studies that were conducted on each sweetener, including studies to assess cancer risk. The results of these studies showed no evidence that these sweeteners cause cancer or pose any other threat to human health.
http://www.cancer.gov/cancertopics/factsheet/Risk/artificial-sweeteners
Does aspartame cause cancer?
...But studies in people can sometimes be hard to interpret, because there may be other factors affecting the results that are hard to account for.
http://www.cancer.org/cancer/cancercauses/othercarcinogens/athome/aspartame
You copy and paste this same post every time the question of artifical sweeteners come up. A blanket statement that there is absolutely nothing wrong with them is simply not true.
You won't get sick, you won't get cancer and you certainly won't get fat.
The fact of the matter is that these substances can and do impact different people in different ways. I have developed a sensitivity/allergy to Sucralose. I can't ingest it. Not even so much as a piece of gum. If I do, I get brutal, rip the muscle off the bone leg cramping from it. It happens every single time I ingest anything with Sucralose and that is the only time it ever happens. I bought into the Sucralose is wonderful narrative and it took months of suffering before my docs and I figured out what was causing the cramping.0 -
I try to avoid putting chems into my body.
So many options for sweetening, maple syrup, honey, agave.
It's a personal choice in my opinion.
Karen0 -
I have 3 splenda's in my coffee each morning. I feel fine. I don't think I have cancer, nor has it inhibited my weight loss.
Some people prefer natural sweeters like honey, agave, or steevia - me, I think they all taste funny. I only drink iced coffee so sugar does not work for me. Splenda it is.
As far as diet soda goes, I prefer to drink a regular soda if I'm going to have soda at all. Diet mountain dew just doesn't compare to the good old original.0 -
I think if kept in moderation, they are ok. I usually have a couple of packets of Truvia every day (with my coffee or tea), I chew sugar free gum every day, and I will drink a diet soda every now and then. Before Truvia came out, I used to use Equal.
My body doesn't react well to Splenda though so I stay away from that.
If you react poorly to artificial sweeteners or feel like they are inhibiting weight loss, don't use them. Otherwise, I don't see an issue with a little every now and then.0 -
I have a small, small amount in my Greek yogurt when I have one with lunch at work. I tend to avoid diet soda, so I don't think the amount I have affects me.
A health-conscious colleague noticed me doing this today and told me to put berries in there instead, and, ref my post: Stress eating, I had to bite my tongue to tell him I was fine with the sweetener.0 -
In case you guys are interested, here is the last study fully available : (Effects of aspartame metabolites on astrocytes and neurons)
https://www.dropbox.com/s/162uz8sf1vb9gf9/Effects of aspartame.pdf0 -
I avoid them- I will take my real sugar, honey, or maple syrup and deal with the extra 30 calories LOL0
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Aspartame turns into formaldehyde in the body. The day I found that out, I quit ALL artificial sweeteners cold turkey. The thought alone is revolting, and now I get headaches or feel really sick when I have anything with them, which says a lot.0
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No sweetener as of yet has been PROVEN to be unsafe.
Some people get migraines or fell ill from consuming sweeteners. If you are fine with them, than still use them. Nothing wrong with them.
Make your decisions based on peer reviewed research and studies... not some random person on the internet or some random article that claims they are bad for you. The only way they have been proven bad is in extremely high amounts in rats... we are not rats nor do most people consume the amount that could potentially cause issues.0 -
Aspartame turns into formaldehyde in the body. The day I found that out, I quit ALL artificial sweeteners cold turkey. The thought alone is revolting, and now I get headaches or feel really sick when I have anything with them, which says a lot.
But, by your profile you are female.. so I assume you use nail polish. Formaldehyde is in nail polish and even though you are not ingesting it, it is still absorbed into your body.
There has yet to be any real, credible research/studies done to prove that sweeteners are bad for us in normal amounts. If you are drinking 24 cans of diet coke a day.. sure that's not the best thing for you but use of sweeteners in moderation are fine provided they don't cause you migraines/sickness.0 -
Artificial sweeteners have unfair rep. They are blamed by overweight people for their weight gain or lack of weight loss. The fact is, people need to be accountable for what they put into their mouth in terms of overall nutrition, not whether they've taken a packet of sweetener. If you want to put some in your tea or coffee or oats, then there is absolutely nothing wrong with doing so. You won't get sick, you won't get cancer and you certainly won't get fat.
That said, I would not recommend diet sodas in place of plain water. But if you want to drink one, then go for it. Just don't go consuming 20+ cans a day. Some people do claim to have headaches when taking aspartame, but I don't know if there is any data to suggest that there is a causal link between consuming aspartame and experiencing headaches.
Aspartame Not Linked to Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797853/
- Saccharin
...there is no clear evidence that saccharin causes cancer in humans, saccharin was delisted in 2000 from the U.S. National Toxicology Program’s Report on Carcinogens...
- Aspartame
...Subsequently, NCI examined human data from the NIH-AARP Diet and Health Study of over half a million retirees. Increasing consumption of aspartame-containing beverages was not associated with the development of lymphoma, leukemia, or brain cancer (2).
- Acesulfame potassium, Sucralose, and Neotame
...Before approving these sweeteners, the FDA reviewed more than 100 safety studies that were conducted on each sweetener, including studies to assess cancer risk. The results of these studies showed no evidence that these sweeteners cause cancer or pose any other threat to human health.
http://www.cancer.gov/cancertopics/factsheet/Risk/artificial-sweeteners
Does aspartame cause cancer?
...But studies in people can sometimes be hard to interpret, because there may be other factors affecting the results that are hard to account for.
http://www.cancer.org/cancer/cancercauses/othercarcinogens/athome/aspartame
...but in 2008, 2012 and 2013 :Studies on the effects of aspartame on memory and oxidative stress in brain of mice.
Abdel-Salam OM, Salem NA, El-Shamarka ME, Hussein JS, Ahmed NA, El-Nagar ME.
Conclusions : These findings suggest impaired memory performance and increased brain oxidative stress by repeated aspartame administration. The impaired memory performance is likely to involve increased oxidative stress as well as decreased brain glucose availability.
In 2008 :Direct and indirect cellular effects of aspartame on the brain
P Humphries1,2 , E Pretorius1 and H Naude´ 1
Conclusion
It was seen that aspartame disturbs amino acid metabolism, protein structure and metabolism, integrity of nucleic acids,
neuronal function, endocrine balances and changes in the brain concentrations of catecholamines. It was also reported
that aspartame and its breakdown products cause nerves to fire excessively, which indirectly causes a very high rate of
neuron depolarization. The energy systems for certain required enzyme reactions become compromised, thus indirectly leading to the inability of enzymes to function optimally. TheATP stores in the cells are depleted, indicating that low concentrations of glucose are present in the cells, and this in turn will indirectly decrease the synthesis of acetylcholine, glutamate and GABA. The intracellular calcium uptake has been altered, thus the functioning of glutamate as an excitatory neurotransmitter is inhibited.
Mitochondria are damaged, which could lead to apoptosis of cells and infertility in men and also a lowered rate of oxidative metabolism are present, thus lowering concentrations ofthe transmitters glutamate and production of GABA.
The cellular walls are destroyed;thus,the cells (endothelium of the capillaries) are more permeable, leading to a compromised BBB. Thus, overall oxidative stress and neurodegeneration are present. From all the adverse effects caused by this product, it is
suggested that serious further testing and research be undertaken to eliminate any and all controversies surrounding this product.
In 2013 :Effects of aspartame metabolites on astrocytes and neurons.
Karol Rycerz, Jadwiga Elżbieta Jaworska-Adamu
Conclusions
This article analyses the direct and indirect role of astrocytes participating in the toxic effects of metabo- lites of aspartame. These glial cells modulate BBB by functional changes in endothelial neutral amino acid transporters. As a result of consuming aspartame, phenylalanine shows a significant affinity for the NAAT transporters in the BBB blocking access for the essen- tial amino acids necessary to the synthesis of dopa- mine and serotonin in the CNS. Astrocytes may play an indirect role in this process.
Aspartate present in excess as a metabolite of aspartame is neurotoxic and it is a substrate for glu- tamate. This amino acid acting on neuronal mGluR receptors and NMDA receptors leads to hyperexcita- bility of cells, free radicals release, oxidative stress and neuronal degeneration. Initially astrocytes are the pro- tectors of neurons and later, with an excess of gluta-
Folia Neuropathologica 2013; 51/1
15
Karol Rycerz, Jadwiga Elżbieta Jaworska-Adamu
mate in the extracellular space, they are activated and release toxic substances intensifying neurodegener- ation.
The methanol, contained in aspartame, is insuffi- cient to bring about alterations in the CNS.
Astrocytes are the source of cancers such as astro- cytoma caused by the carcinogenic effect of diketo- piperazine.
Further research of aspartame’s impact on the mor- phology and function of astrocytes and neurons is nec- essary to be carried out.
Don't you think it's a little odd for a sweetener that has been synthesized in 1965 that there is so much controversy ? Not to mention the FDA is the first one to claim it's non-toxicity, but at the very same time states about Stevia :FDA has not permitted the use of whole-leaf Stevia or crude Stevia extracts because these substances have not been approved for use as a food additive. FDA does not consider their use in food to be GRAS in light of reports in the literature that raise concerns about the use of these substances
Edit : a bit of history regarding Aspartame approval :It is no coincidence that the FDA Chairman who stood in the way of aspartame's approval was removed from office the day Ronald Reagan took office. His replacement (Dr. Arthur Hill Hayes) was in part planted there by Donald Rumsfeld, CEO of G.D. Searle (aspartame is produced by G.D. Searle Company), in order to allegedly get a friendly rubber stamp on aspartame's approval.
But even with a friendly new FDA Chairman in place, the agency still rejected aspartame for approval by a 3-2 margin. What reprehensible, bordering on criminal action did Chairman Hayes do next? He added a sixth member to the approval board, who voted in favor of aspartame. Then, with a 3-3 tie on the issue, Chairman Hayes himself broke the deadlock with his own vote of approval for aspartame.
So he packed the board and then used his own vote as a tie-breaker. All apparently perfectly legal ...
And one of Hayes' last acts in office before he left the FDA in1983 amid accusations that he was accepting corporate gifts for political favors, was to approve aspartame for use in beverages. Does this sound to you like a man-made synthetic chemical that should have never been allowed into the world's food supply?
Those "studies" are hilarious.
The first used massive amounts directly injected into mice, and the other two were merely hypothetical wanking about the possible pathways (and they actually listed alarmist aspartame websites under their references).
Edit
Both the 2008 and 2013 actually referenced this site:
http://www.wnho.net/
Seems legit.0 -
Really ?
2008 :
Direct and indirect cellular effects of aspartame on the brain.
http://www.ncbi.nlm.nih.gov/pubmed/17684524
2013 :
Effects of aspartame metabolites on astrocytes and neurons.
http://www.ncbi.nlm.nih.gov/pubmed/235531320 -
If you take those kind of artificial of any kind, there always be a side effect. That's why it's artificial.
Whaaa? :huh:0 -
I tend to agree with Sweet_Pandora, we have the datas, and you'll find as many as studies as you want that will tell you that compound is safe....as you will find as much telling you Aspartame is dangerous...we all know the litany here.
Everyone is free to draw his own conclusions based on the information that is available out there, that's it.0 -
Really ?
2008 :
Direct and indirect cellular effects of aspartame on the brain.
http://www.ncbi.nlm.nih.gov/pubmed/17684524
Several unreliable sources (including wnho.com and healingarts.org) and misuse of several others.2013 :
Effects of aspartame metabolites on astrocytes and neurons.
http://www.ncbi.nlm.nih.gov/pubmed/23553132
Cites WNHO twice, as well as Dorway.com (another alarmist website).
Not a single human study has shown any effect. The only studies that had any measurable effect were done on rats, and the doses were well beyond the recommended safe intake level (often by orders of magnitude).
Crit Rev Toxicol. 2007;37(8):629-727.
Aspartame: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies.
Magnuson BA, Burdock GA, Doull J, Kroes RM, Marsh GM, Pariza MW, Spencer PS, Waddell WJ, Walker R, Williams GM.
Source
Burdock Group, Washington, DC, USA. bmagnuso@umd.edu
Abstract
Aspartame is a methyl ester of a dipeptide used as a synthetic nonnutritive sweetener in over 90 countries worldwide in over 6000 products. The purpose of this investigation was to review the scientific literature on the absorption and metabolism, the current consumption levels worldwide, the toxicology, and recent epidemiological studies on aspartame. Current use levels of aspartame, even by high users in special subgroups, remains well below the U.S. Food and Drug Administration and European Food Safety Authority established acceptable daily intake levels of 50 and 40 mg/kg bw/day, respectively. Consumption of large doses of aspartame in a single bolus dose will have an effect on some biochemical parameters, including plasma amino acid levels and brain neurotransmitter levels. The rise in plasma levels of phenylalanine and aspartic acid following administration of aspartame at doses less than or equal to 50 mg/kg bw do not exceed those observed postprandially. Acute, subacute and chronic toxicity studies with aspartame, and its decomposition products, conducted in mice, rats, hamsters and dogs have consistently found no adverse effect of aspartame with doses up to at least 4000 mg/kg bw/day. Critical review of all carcinogenicity studies conducted on aspartame found no credible evidence that aspartame is carcinogenic. The data from the extensive investigations into the possibility of neurotoxic effects of aspartame, in general, do not support the hypothesis that aspartame in the human diet will affect nervous system function, learning or behavior. Epidemiological studies on aspartame include several case-control studies and one well-conducted prospective epidemiological study with a large cohort, in which the consumption of aspartame was measured. The studies provide no evidence to support an association between aspartame and cancer in any tissue. The weight of existing evidence is that aspartame is safe at current levels of consumption as a nonnutritive sweetener..0 -
Isn't it kind of silly to just sit here posting different studies back and forth at eachother? Honestly?0
-
You copy and paste this same post every time the question of artifical sweeteners come up. A blanket statement that there is absolutely nothing wrong with them is simply not true.
You won't get sick, you won't get cancer and you certainly won't get fat.
The fact of the matter is that these substances can and do impact different people in different ways. I have developed a sensitivity/allergy to Sucralose. I can't ingest it. Not even so much as a piece of gum. If I do, I get brutal, rip the muscle off the bone leg cramping from it. It happens every single time I ingest anything with Sucralose and that is the only time it ever happens. I bought into the Sucralose is wonderful narrative and it took months of suffering before my docs and I figured out what was causing the cramping.
Thanks for pointing this out to me. I copy and paste that because for, say, 90% of people it is true. The other 10%, like yourself, have a problem with it. It's the same thing as if I said:
It's okay to eat eggs. You won't get sick, you won't get cancer and you certainly won't get fat.
This statement is true. Most people do not have an allergic reaction to eggs. BUT, of course you must consider that 1 person may have an allergy, you must consider that I am not implying it's okay eat 100 eggs a day and you must consider that I am not implying it's okay not train and eat a balanced, nutritionally dense diet.
My point is that it's okay to have sweeteners, provided you are not allergic to them. As you have made a fair point, I will in the future add the caveat that some people are allergic to sweeteners and that one should experiment with them and get their doctor's approval before using them.0
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