orlistat

Hmm... First of all, all drugs are toxic to the liver. So unless there is a real medical need for taking them (like my mom on high blood pressure meds, for instance), then I would avoid them.

I'm not a doctor, but Wikipedia told me that the way this helps is to reduce fat absorption, so that you absorb fewer calories than you eat. Wouldn't it just be easier to cut back on the amount of fat in your diet and skip the pill? But it seems you are already eating a rather low-fat diet, so I'm not sure why you are even taking such a pill.

Also, scanning through your diary for the past week, I have noticed 2 things:

1) You are short pretty much every day, sometimes significantly.
2) You are either eating way too little some days, or not logging everything you eat.

So that means one of two things: Either you are not logging everything you eat, which means you are probably eating at maintenance or above most days, or you ARE logging everything you eat, which means you are short on calories and in the notorious "starvation mode." Call it what you will, but if you are consistently eating below your BMR, then you are not going to lose. Your body will just hang onto everything and slow your metabolism down to compensate for the reduction of food intake.

If I were you, I would look at that, and then fix whichever issue it is; either eat consistently closer to your goal, or log everything you eat. Give it a couple of weeks, then reassess. And cut out the drug! It's obviously not working!