Levothyroxine and weight GAIN?

frayedpages0320
frayedpages0320 Posts: 8 Member
edited November 12 in Health and Weight Loss
Hi, all. I was wondering if anyone else has taken levoythyroxine and experienced weight gain as opposed to loss?

Several months ago, my endocrinologist had my thyroid levels tested. She said they were *just* under what is considered "normal" and that if it weren't for my prolactinoma, she wouldn't be treating for hypothyroidism at all. (She thinks the size of the tumor is impacting my thyroid function.) I started Levothyroxine in February. When I went to my endocrinologist in February, I had actually lost 7lbs. When I saw her last week (5 months later), I had somehow gained weight -- about 10lbs worth. I asked her if it could be related to the levo, and she said no -- and then said that it was something that I had caused, even though I really haven't changed anything - if anything, I have actually become more active because I'm working more (retail) instead of sitting in school all day. Now, she wants to test for Type 2 Diabetes and a slew of other things and is contemplating putting me on another medication to "control my weight." I really don't want to take a third medication.

Has anyone experienced something similar? Also, has anyone who has combined levothyroxine with cabergoline had any side effects related to weight?

Thanks,

FrayedPages0320
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Replies

  • MyaPapaya75
    MyaPapaya75 Posts: 3,143 Member
    I take Levo....100mcg....u have to take it before your meal in the morning 30min to 1hr ...I have no weight gain but Im diligent as to when I take the pill. Not sure if this has anything to do with it. I was also Type 2 Diabetic but ate right and lost weight to get my A1c within normal range.
  • frayedpages0320
    frayedpages0320 Posts: 8 Member
    I'm really not sure if timing has to do with it. I take it everyday as prescribed, and I always try to make sure that I have enough time between taking my meds and eating in the morning, but sometimes that just can't happen. It's either take the meds and not eat breakfast and not be able to eat until much later in the day or risk absorption and eat breakfast and not starve myself. So, maybe.

    What gets me, though, is that my weight has been pretty stable throughout high school (just graduated this year). I finally started to lose some weight and then my endo put me on levo and BAM - weight gain. I'm just really confused.
  • shadow2soul
    shadow2soul Posts: 7,692 Member
    Lets look beyond the medication for a moment:

    1) How recently did your activity level increase?
    2) What about sodium levels before the weigh in?
    3) When you weighed were you wearing similar outfits at each appointment? (jeans can weigh 5lbs)
    4) Have you been taking measurements? If so have the decreased or increased?
    5) Do you weigh your food with a kitchen scale?
    6) Have your calorie goals changed? (usually need to be adjusted between 5-10lbs of loss)
    7) Have you been drinking enough water? (pale yellow/clear pee)
    8) Have you started any new workouts recently? (especially if its weights or strength related)
  • frayedpages0320
    frayedpages0320 Posts: 8 Member
    My habits before February and after February had remained the same.

    1. June
    2. No clue. I'm not consistent with MFP, and I don't keep track any other place.
    3. Yes - I always wear the same stuff.
    4. No measurements.
    5. No.
    6. No change.
    7. I never drink enough water.
    8. Nope.
  • trudijoy
    trudijoy Posts: 1,685 Member
    I take levo (eltroxin) and it's never affected my weight either way.

    Are you having digestive issues? That goes along with the thyroid and 99% of the time if I gain weight its just that.
  • shadow2soul
    shadow2soul Posts: 7,692 Member
    My habits before February and after February had remained the same.

    1. June
    2. No clue. I'm not consistent with MFP, and I don't keep track any other place.
    3. Yes - I always wear the same stuff.
    4. No measurements.
    5. No.
    6. No change.
    7. I never drink enough water.
    8. Nope.

    I think maybe the possibility is a combination of a few things.

    Sodium is possibly on the high side. Combine that with not drinking enough water and you end up with water retention.
    Possibility of over-eating. In the amount of time that you gained, its only like an extra 25 or so calories per day since feb. There could also be a little water retention in your muscles from the increased activity.

    I'd try tracking your calories, consistently for a month or so.
    Oh and I forgot to ask, How do your clothes fit?
  • Fuzzipeg
    Fuzzipeg Posts: 2,301 Member
    a general thought. Something which can upset the body is salicylate. Most often the medical profession do not consider this to be a problem but as it is toxic in many people, to a greater or lesser extent it might be something worth look/read into. I mention this because weight gain, thyroid issues and irritable bowel are amongst the list of things which can cause any one person problems when their body is distressed.

    There is the "food can make you ill" website which looks at the affects foods can have on the body and this gives all the possible symptoms which are attributable to salicylate as well as the other things like amines. There is also a book of the same name which is available digitally. There is also the "Saliclyate sensitive" web site too, some there have picked it up with minimal reactions. The initial, key work into Salicylate was carried out in Australia or New Zealand by Anne Swain and fellow dietitians, others world wide have contributed to the increasing body of work in this area.

    I discovered salicylate in my 60's having had many other symptoms as well as those above, many are now happily resolved but I will never be re balanced. Someone who is younger has the potential to radically reduce the extent of possible damage. I have improved from the point of being in great pain in various joints which got worse with medication, no pain in knees now. I am no longer bloated, reduced with effort by 6-7 stone and still more to go. I am happier in myself, been told I was depressed, accepted it because I knew no better, and felt the cold so severely, that with other issues caused my thyroid to be tested and found wanting. I refused to take thyroxine because it contained maize starch as the binder. Maize starch is moderate in salicylate but one tablet a day bloated me, took my breathing, produced joint pain and made me lethargic. I bolstered my iodine intake by eating cod and tuna to support my thyroid. This would not be safe for many, but it was all I could do when I was told by the allergist to, " take the pill and take something else for the breathing and all", because salicylate does not have a normal allergic reaction, crudely put it has a poisoning effect . I still have skin flair ups but they resolve very easily though strong perfumes has caused me to need to sleep the effects off.

    Please read up on salicylate sensitivity, I was affected from childhood. Knowing what to look out for might help you or others.

    all the best
  • ALittleSwanny
    ALittleSwanny Posts: 36 Member
    I take 100mg of Levothyroxine and I have struggled with my weight more since being diagnosed than ever before!
  • frayedpages0320
    frayedpages0320 Posts: 8 Member
    I really wasn't expecting so many responses! Thank you!

    I should probably mention that I take 50 mcg a day. I don't know if that makes a difference.

    I feel fine - no difference than before I started the meds. If anything, I'm having a harder time sleeping. Otherwise, no digestive problems, nothing.

    With the water retention - it is a possibility, and I'll have to pay more attention to it. However, I haven't been keeping hydrated for years. I also play soccer during the school year, so I wasn't completely inactive before hand.

    My clothes fit fine. I actually didn't notice the weight gain until my doctor said something about it.


    ALittleSwanny-- What have you experienced? I have tried to do research this, but there isn't a lot. Most places say that Levo should, if anything, cause weight loss. However, I have come across some people who have a similar experience - no life/diet changes, added levo, and sudden weight gain.
  • beemour
    beemour Posts: 2
    I also take levothyroxine (150mg/day). I have learned that it is critical to take it at the same time every day, with respect to meals, because empty v. full stomach affects how it is absorbed. This can throw off your levels.

    I have read in many, many books and articles that it is just plain harder to lose weight at all when you have a thyroid problem (Thyroid Sourcebook is a good resource). If you have access to a nutritionist or dietitian, maybe through your endo, I have found that they're very helpful. Most books I've read recommend a low-GI diet for hypothyroid patients wanting to lose weight. And patience. Lots and lots of patience.
  • frayedpages0320
    frayedpages0320 Posts: 8 Member
    I admit, I am not super regular with my medicine; that is, I take it everyday, but not always at the same time. But would this make me gain weight when I was previously losing weight? I'm genuinely confused....
  • frayedpages0320
    frayedpages0320 Posts: 8 Member
    So, I spoke to the nurse at my regular doctors office, and she said she thinks the whole thing is a little weird. She suggested that I call my endo and try to talk to her again. If any of you are interested, I can post her response.

    I appreciate all the help that you all have given. :)
  • Marla64
    Marla64 Posts: 23,120 Member
    I had weight gain on Levo, too--

    Has your endo checked your antibodies for Hashimoto's? That is what I have-- autoimmune disorder where your body attacks the thyroid. Hypothyroidism is number one symptom-- after over a year, my doctor finally checked.

    Treatment doesn't change much-- but there is more info out there to help you navigate confusing waters once there is a name.

    I'm on Armour right now, which is a combination of T4 hormone (Levo) and T3 (Cytomel)

    Gain stopped-- but I have to be incredibly diligent to lose anything. If I limit carbs to 50g a day, no gluten, no sugar, no dairy, I have been able to take off weight.

    Look into Armour, and check out Hashi-- and don't take no for an answer when your doctor balks-- because she will.
  • Marla64
    Marla64 Posts: 23,120 Member
    Also, I've read that taking Levo at night before bed (assuming you haven't eaten for at least one hour) works very well. I tried taking mine at night, and did feel much better-- unfortunately, summer time has equaled snack time...my stomach is never empty at bedtime. :embarassed:
  • socajam
    socajam Posts: 2,530 Member
    So, I spoke to the nurse at my regular doctors office, and she said she thinks the whole thing is a little weird. She suggested that I call my endo and try to talk to her again. If any of you are interested, I can post her response.

    I appreciate all the help that you all have given. :)


    Like most of the people on here said, you should take the medication first thing in the morning will a fulll glass of water on an empty stomach. I was on levoylx, not taking synthroid (had my thyroid take over 20 years ago), always take my medication on an empty stomach.

    Some times I set my clock for 30 minutes earlier to take the medication so that I can have breakfast at a set time. Take the water to bed, so everything is right at hand.

    You are going to have to revamp what you normally eat, because it is going to be very easy to put on weight. Stay away from white stuff (flour, bread, processed food, high sodium foods, sodas etc). I have changed the way I eat over the years, now I am very serious about portion control. I find if I exercise, that helps to stabilize my weight, but to lose weight, I have to exercise really hard, for example 30 minutes of slow walking will do not for anything for me. I really have to ramp it up to a higher level. Its not the end of the world, but it a change in how you are going to live your life in the future.
  • Yes I take this medicine since I used it I have gain 30 pounds can't lose it no matter what I try I walk 6 days a week no carbs still can't loose its the medicine imam planning to stop taking it
  • Heavybetty
    Heavybetty Posts: 38 Member
    bump for later
  • Fara_n_KY
    Fara_n_KY Posts: 1 Member
    I was recently diagnosed with hypothyroidism and prescribed this medication. I found
    It to be useless as it did not treat my symptoms. The issue I suspect I am
    Having is converting T4 into T3 because I have elevated T4 and low T3. However my reg doc won't prescribe anything except Synthroid so I am waiting for an app with a specialist. I remain exhausted and gained 5 lb bc my doc did not run
    Labs for T3 and T4. Frustrating!
  • wendym77
    wendym77 Posts: 1
    I recently started on a small dose of levothyroxine and after the second week I had gained nearly 2kg (5lbs)! I eat a healthy vegetarian diet and jog 40 minutes/day at least 3 times per week. I also do a fair amount of easy cycling and walking during the week. I am trying to hold out for the 6th week so that my levels can be tested again, but this sucks! I don't notice much difference except maybe a slight improvement in my hair, nails, and skin. My last TSH reading was 5.7, so subclinical. Has anyone else had this weight gain at start of treatment? Did it reverse itself eventually?! Did you stop taking the meds?
  • BeverlyJeanHohm
    BeverlyJeanHohm Posts: 1 Member
    I just started on levothyroxin 50 mcg daily. I was just diagnosed with Hashimoto's last week... So am very new to this. I am in the middle of menopause and 53. I have been sluggish,depressed, cold and gained 5 to 6 pounds over this past year while watching my weight and continuing to exercise diligently if I had always done my whole life. Since starting the medication a few days ago I have gained 2 pounds. I do feel a little bit more energy and not as depressed but am discouraged about the weight gain. I was hoping to finally see the scale called the other direction! I really appreciate this site! I really need encouragement right now if I am feeling very discouraged! Thank you for all of your helpful information. I appreciate the tip about getting up three hours early and taking the medication.. Will have to try that. Has anyone had trouble with night sweats increase after this medication? Blessings to all of you!!
  • nancypetrina
    nancypetrina Posts: 1 Member
    I have literally the exact same story. I went to the DR in February, got my levels tested (came back just under normal), and was put on Levothyroxine. I went back for my checkup yesterday and i gained 6 lbs! Granted, last time I was there I was weighed in the morning and yesterday it was at 5pm. I am also hungry ALL The time!! I generally eat pretty well and I exercise every day. I know there are times when I probably eat more than I should, but definitely not enough to gain 6 pounds in a short amount of time. It's really weird. Could it be causing water retention? I am only 5'2'' and all of my clothes still fit- 6 pounds on someone my size generally shows when we try to button our pants lol
  • editorgrrl
    editorgrrl Posts: 7,060 Member
    MFP has a Hypothyroidism and Hyperthyroidism group: http://www.myfitnesspal.com/forums/show/770-hypothyroidism-and-hyperthyroidism

    I kept gaining weight after I was diagnosed with Hashimoto's (autoimmune thyroid disease) and started taking Synthroid. Once I started logging everything I eat accurately & honestly, I realized I was eating too much. (I'm always hungry.)

    I lost way more slowly than most MFPers (20 lbs. in a year), but I did it just like everybody else—by eating at a deficit.

    Read this: http://www.myfitnesspal.com/topics/show/1080242-a-guide-to-get-you-started-on-your-path-to-sexypants
  • Keiras_Mom
    Keiras_Mom Posts: 844 Member
    Also, I've read that taking Levo at night before bed (assuming you haven't eaten for at least one hour) works very well. I tried taking mine at night, and did feel much better-- unfortunately, summer time has equaled snack time...my stomach is never empty at bedtime. :embarassed:

    I keep mine in a little dixie cup on my nightstand and take it whenever I wake up in the middle of the night. I don't have to worry about meals/caffeine/dairy, etc. when I do it this way. I mentioned to my endo at my last appointment that this is how I take mine, and she said it's perfect.

    Now if you sleep through the night, it obviously won't work. :wink:
  • Marla64
    Marla64 Posts: 23,120 Member
    Also, I've read that taking Levo at night before bed (assuming you haven't eaten for at least one hour) works very well. I tried taking mine at night, and did feel much better-- unfortunately, summer time has equaled snack time...my stomach is never empty at bedtime. :embarassed:

    I keep mine in a little dixie cup on my nightstand and take it whenever I wake up in the middle of the night. I don't have to worry about meals/caffeine/dairy, etc. when I do it this way. I mentioned to my endo at my last appointment that this is how I take mine, and she said it's perfect.

    Now if you sleep through the night, it obviously won't work. :wink:

    That's a great idea-- I already keep it on my desk in my bedroom--
  • JillLynnJohnston
    JillLynnJohnston Posts: 6 Member
    I was started on 25 mcg of levothyroxine by a stand-in OB/GYN (could not get in to see mine) who wanted to "tweak" my thyroid since I was so fat. I went along with it, but it did absolutely nothing. That was about five years go. 225 pounds lost later, I have had extreme thinning of my hair and just saw an endocrinologist yesterday, also constipation/severe gas (sometimes associated with hypothyroidism).

    The endocrinologist's office just advised me to stop taking the levothyroxine after looking at my serum thyroid studies. OH MY GOSH! I am scared, even though every one of my 225 pounds was lost through GREAT intention! Not this silly pill.

    My doctor said my hair loss could be from the shock of my weight loss, even though it has been with excellent nutrition and lots of cardiovascular exercise (mostly running). I am freezing all the time, and again it was attributed to my weight loss (my "insulation" is gone).

    My hair loss, it turns out, could actually be from taking levothyroxine. I am just so scared that coming off of this medication could somehow be detrimental to my weight loss. I have easily maintained my weight for nine months after making lifelong changes, but what if I "psych" myself out or something??
  • editorgrrl
    editorgrrl Posts: 7,060 Member
    Don't panic! You lost the weight by logging everything you eat & drink accurately & honestly—and you will keep it off the same way.

    You have all the skills you need to maintain your weight—you've done it for nine months already. As you've already learned, your weight will fluctuate in maintenance. Do not let it freak you out.

    Feel free to friend me.
  • kevinsmithrn
    kevinsmithrn Posts: 70 Member
    I've had Hashimotos for years and my pre- medicated tsh level was unbelievable. In my experience the levo will only suppress the sluggishness and thus allow you to excercise. Most people think it's the answer to their obesity - nothing can be further from the truth. More important than how u take it - an hour before breakfast etc.. Just always take it the same way - that way your md can adjust your medicine and it can stay adjusted. I take 250 mcg and I get up take my meds - take a shower - dress then eat breakfast... Elapsed time around 20 mins - if I waited a bit longer then ate I could probably get my dose age down a bit - but this has worked for me for years. The biggest change I notice is mental clarity - when my tsh is off it's difficult to remember the easy things - like u have yo think harder than usual to remember a name or perform a simple math operation - excercise does more for energy level than levo ever did. Good Luck!
  • kyame1971
    kyame1971 Posts: 1 Member
    Yes, I gained 30 lbs after being on the med for 6 months. I was also hospitalized and had heart palpitations. Doctor that prescribed stated my dosage was so low it couldn't possibly cause weight gain or heart palpitations. It must be because I'm eating too many carbs and not exercising enough. Got another opinion and an endocrinologist determined that my thyroid was normal and never should have been given med. A Rheumatologist diagnosed rheumatoid arthritis, which is an autoimmune disorder. She also tested my thyroid and determined it was normal. Cardiologist and endocrinologist both confirmed this med could cause these issues especially if thyroid is normal. I was also active and following a low carb low fat Mediterranean diet. After seeing cardiologist, endocrinologist and rheumatologist I'm convinced it was the levothyroxine that caused my weight gain and heart palpitations. Now the heart palpitations are gone. Receiving treatment for the other issues due to RA and changed to a anti-inflammatory diet. Still doing moderate to vigorous exercise daily. Hoping to see weight loss soon.
  • cameronita1
    cameronita1 Posts: 1 Member
    Hi I just started Levo after 4 years of being off of it. I was on Nature Throid and gained weight. I take Cytomel with my Levo and so far have noticed no weight gain. But if I do I will tell my doctor I want something else. She also has me on biodentical cream for progesterone only cause she said I am still estrogen dominant. So we are working on that to correct that imbalance. I think the imbalance of estrogen/progesterone ratio has something to do with balancing out the thyroid. I was 203 before starting progesterone cream. I am now 185. But it has taken me almost 5 years to lose 17 pounds due to still being estrogen dominant.
    We did discover that my thyroid is not making any T4 or T3 so I have to take both. I sure hope you all here find a good solution. I just wanted to relate my experience of balancing not only the thyroid hormones but also the progesterone/estrogen ratio. Like I said I have began losing weight when I started taking natural progesterone and beginning to combat my estrogen dominance. But it is a constant battle just like you all! Good luck and my prayers are with you all.
  • CMNVA
    CMNVA Posts: 733 Member
    I've been on levothyroxine for over 20 years and it never caused me to gain weight. I had to have my thyroid removed due to cancer so maybe that makes a difference. Some things I've learned, heard from endocrinologists:

    1. Taking too much can make you hyperthyroid very quickly. Often one assumes that if you go hyper, that you will lose weight. My doctor told me that most people, unknowingly, start compensating and eating more. Being hyper makes you hungry. So, OP, it's time to honestly log your food and see if being on this medication has driven you to eat a little more. The medication itself is a hormone and won't directly cause weight gain.

    2. Taking your meds. The common advice is to take the the medication first thing in the morning on an empty stomach and wait an hour to eat anything else. The reason for this is that many things can interfere with the absorption of this very sensitive hormone. Milk and soy are huge T4 blockers as are some vitamins. BUT....as I was told, if you cannot possibly do that, make sure that you take your medicine the same "way" everyday. If you have to take it with food or only have a 15 minute window, that's okay. But do that everyday. Yes, your food will likely interfere with the meds so instead of needed 100 mcg per day, you might need 112 mcg per day. That's okay.

    3. You can take thyroid medication at bedtime provided you haven't eaten for several hours. For some people, there is a period of time where the T4 floods the bloodstream and it *may* interfere with sleep. Other people are not bothered.

    4. Always know your numbers. Your doctor told you your levels are little below normal. Find out the lab reference range and where you number fell. Know it and watch what happens on future labs. Learn what number is your sweet spot.
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