Paleo Diet Assoc With NegChanges to BloodLipid in HealthySub
Acg67
Posts: 12,142 Member
https://kb.osu.edu/dspace/bitstream/handle/1811/54660/E_Trexler_Thesis.pdf?sequence=3
Dietary Intervention
A Paleolithic diet, as first described by Eaton and Konner, was implemented for all study
participants [16]. Subjects were advised to increase their consumption of lean meat, fish,eggs,
nuts, fruit, and vegetables and were instructed to strictly avoid all grains, dairy
products, and legumes. All modern, processed foods including any form of processed
sugar, soft drinks, and coffees were also excluded from the diets of the subjects. No
specific macronutrient recommendations were made, as the study design wanted to
closely mimic a real world model that would incorporate food choices made by the
average consumer. Intake of specific proportion of food categories (e.g. animal vs. plant
foods) was also not given. Dietary recall logs were distributed to all subjects during the
last week of the dietary intervention and subjects were asked to record all food and
liquids over three days, including a weekend day.
Conclusion:
In conclusion, our study shows that the Paleo diet was significantly deleterious to blood
lipid profiles in healthy subjects concurrently participating in a CrossFit-based, highintensity
circuit training program. Specifically, subjects with optimal initial blood lipid
values demonstrated the greatest increase in LDL, TC/HDL, TC, and n-HDL values,
along with the greatest decline in HDL values, following the 10-week Paleo diet
intervention. Despite concurrent improvements in aerobic capacity and body composition
noted in these subjects, the Paleo diet may have negated the positive effects of exercise
on blood lipids.
Dietary Intervention
A Paleolithic diet, as first described by Eaton and Konner, was implemented for all study
participants [16]. Subjects were advised to increase their consumption of lean meat, fish,eggs,
nuts, fruit, and vegetables and were instructed to strictly avoid all grains, dairy
products, and legumes. All modern, processed foods including any form of processed
sugar, soft drinks, and coffees were also excluded from the diets of the subjects. No
specific macronutrient recommendations were made, as the study design wanted to
closely mimic a real world model that would incorporate food choices made by the
average consumer. Intake of specific proportion of food categories (e.g. animal vs. plant
foods) was also not given. Dietary recall logs were distributed to all subjects during the
last week of the dietary intervention and subjects were asked to record all food and
liquids over three days, including a weekend day.
Conclusion:
In conclusion, our study shows that the Paleo diet was significantly deleterious to blood
lipid profiles in healthy subjects concurrently participating in a CrossFit-based, highintensity
circuit training program. Specifically, subjects with optimal initial blood lipid
values demonstrated the greatest increase in LDL, TC/HDL, TC, and n-HDL values,
along with the greatest decline in HDL values, following the 10-week Paleo diet
intervention. Despite concurrent improvements in aerobic capacity and body composition
noted in these subjects, the Paleo diet may have negated the positive effects of exercise
on blood lipids.
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I don't care what my personal opinion is, I can't get enough of this .gif
I'm dying of laughter...'cause *kitten*'s about to get real. LOL0 -
Them long words is making me head hurt!
Thanks for the link and the summary--glad to see a study that attaches some numbers to common sense. Though I do not think this will convince elimination diet fanatics who are convinced that grains, legumes and dairy are evil.
Edit: too bad it isn't peer-reviewed or published (though I see it was only just finished)--I hope they publish it soon, and maybe the CrossFit/Paleo folks will notice.0 -
Ideal physique
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One thing I noted from the study is that only 8 people out of the 43 turned in a usable food log. If they weren't willing/dedicated/observant/whatever enough to fill out a 3 day food log, it is hard to imagine that they were sticking to even the minimal Paleo guidelines they were given. Without knowing what these people were actually eating it is a stretch to cry foul on Paleo as a whole. Sure, they gave it a nice spin by talking about seeing how a free-living Paleo eater would do, but that kind of approach is pretty poor science.
I also found it interesting that they took the before and after measurements within 1-5 day periods before and after the test period. I expect that you could see a statistically significant change in a number of those measures over 5 days, seems like another sign of poor study design to have a variable and possibly lengthy delay.0 -
One thing I noted from the study is that only 8 people out of the 43 turned in a usable food log. If they weren't willing/dedicated/observant/whatever enough to fill out a 3 day food log, it is hard to imagine that they were sticking to even the minimal Paleo guidelines they were given. Without knowing what these people were actually eating it is a stretch to cry foul on Paleo as a whole. Sure, they gave it a nice spin by talking about seeing how a free-living Paleo eater would do, but that kind of approach is pretty poor science.
I also found it interesting that they took the before and after measurements within 1-5 day periods before and after the test period. I expect that you could see a statistically significant change in a number of those measures over 5 days, seems like another sign of poor study design to have a variable and possibly lengthy delay.
Agreed^.
A study of only 43 people. And they were advised to eat "lean" meat (so probably avoided fat) and they were not observed. Most people I know eating SAD wouldn't have a clue what foods to eliminate if they were told to eat no grain, legumes, or dairy. A three day food diary, that only a few people completed? Some study. There's no way to determine "causation" in such an uncontrolled study.
As long as I have been here on MFP, I fail to figure out why the OP is so against a lifestyle that promotes consuming more natural foods, and less processed foods. The OP keeps pushing that the paleo/primal/keto lifestyle is unhealthy when logically, by avoiding processed foods, it can't help but be healthier than SAD. I'm thinking the OP might be on the payroll of one of the big food manufacturers. I can find no other explanation.
There are far more than 43 primal/paleo/keto people here who have shared their before and after blood work, and there is much change. Most notably in triglycerides and LDL/HDL ratios. (Surely the OP knows that total cholesterol is a meaningless number and does not predict heart disease.)
OP: congratulations on all the hard work you do to turn people away from a lifestyle that may extend their life, or at the very least, vastly improve quality of life. I'm sure that the pharma/food processing/chem industries are all very thankful. Sick/fat people are great for profits. :drinker:0 -
A study of only 43 people. And they were advised to eat "lean" meat (so probably avoided fat) and they were not observed. Most people I know eating SAD wouldn't have a clue what foods to eliminate if they were told to eat no grain, legumes, or dairy. A three day food diary, that only a few people completed? Some study. There's no way to determine "causation" in such an uncontrolled study.
A study with 43 subjects can have sufficient statistical power if the right kind of data are collected from each subject. I would be more worried about their use of t-tests for statistical analysis. For a design like this, you would want to use a hierarchical linear regression (i.e., a mixed effects model) to allow the regression slope for the dependent variable to vary by participant. This is something that a decent peer-reviewed journal would probably make them do. The graphs also do not provide sufficient information as to the amount of variance; the error bars go in one direction only. Still, the effect size seems to suggest that the results will hold up even in a more rigorous analysis.As long as I have been here on MFP, I fail to figure out why the OP is so against a lifestyle that promotes consuming more natural foods, and less processed foods. The OP keeps pushing that the paleo/primal/keto lifestyle is unhealthy when logically, by avoiding processed foods, it can't help but be healthier than SAD. I'm thinking the OP might be on the payroll of one of the big food manufacturers. I can find no other explanation.
That is probably because you are assuming that there are only two alternatives: SAD vs. Paleo. There are many, many other ways to eat besides SAD: the Mediterranean diet, which has been the subject of good rigorous studies; many vegetarian diets; a flexible diet of whole foods that does not impose restrictions against grains, legumes, and dairy; etc., etc.There are far more than 43 primal/paleo/keto people here who have shared their before and after blood work, and there is much change. Most notably in triglycerides and LDL/HDL ratios. (Surely the OP knows that total cholesterol is a meaningless number and does not predict heart disease.)
References?OP: congratulations on all the hard work you do to turn people away from a lifestyle that may extend their life, or at the very least, vastly improve quality of life. I'm sure that the pharma/food processing/chem industries are all very thankful. Sick/fat people are great for profits. :drinker:
Again, you are assuming a false dichotomy. See above.0 -
I know I'm very late to this party, but I've been Paleo for almost two years and my blood lipid profiles improved dramatically within the first 30 days and have continued to improve. Before going Paleo I was pre-diabetic and my triglycerides were high as was my blood pressure. I worked out like mad before and followed a Mediterranean diet. Nothing worked for me health-wise, but the Paleo diet. Now all my blood test results are excellent.
I should note that before eating Paleo I have tried: The Blood Type Diet, Weight Watchers, NutriSystem, Atkins and the South Beach Diet. On almost every diet I would lose about 6-9 pounds in the first 60-90 days and then gain it all back even though I was very strict with it and worked out. I felt horrible on Weight Watchers, NutriSystem and Atkins. I felt pretty good on the Blood Type Diet and the South Beach Diet. By far, I feel the most energy on Paleo.
Another important thing is that many people who try the Paleo diet aren't doing it right at all. They gorge on fat and protein and forget that you're supposed to eat a ton of veggies. I eat veggies all day long, even at breakfast.
I have fibromyalgia and hypoglycemia. Because of my body's inflammation response, it is almost impossible for me to lose weight so I still struggle with that, but I feel a zillion times better and if you believe my blood tests, I'm much healthier.
My work recently did a fitness challenge and even though borderline obese in the weight charts, I was healthier than almost anyone else. My oxygen intake was at elite athlete level.
I eat almost exclusively organic foods (I would say 90% organic). I have wondered if this has something to do with it.
It was so easy to do a Mediterranean diet, but a Paleo diet is tremendously difficult to do and crazy expensive. I'm very strict with it. I probably eat Paleo 95% of the time. When I don't, my pain flares up and I have stomach issues.
However, I don't think any one diet helps everyone. You have to find what works for you.
That's my two cents...0 -
Akimajuktuq wrote: »And they were advised to eat "lean" meat (so probably avoided fat) and they were not observed.
Actually the study says that they were eating an "ad libitum application of the Paleo diet, without restrictions on intakes of fatty meat, eggs, nuts, and oils".
What is noticeable is that ALL those 43 partecipants were doing crossfitt. It is not told if they started crossfitt and paleo at the same time, but as far as I know, crossfitt is a pretty stressful routine, so it is likely that the worsening of the lipid profile is due to the oxidative stress of their work-out (a control group would have told us...).
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herrspoons wrote: »Fad diet has unforseen side effects?
Well there's a surprise!
Well, to be fair, there are a lot of things about the study that I've seen picked apart about other studies, like small sample size and self-reporting.
Saying that, it's certainly a finding that would call for further study.
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I wonder if anything new has turned up since this thread was posted in 2013.0
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diannethegeek wrote: »I wonder if anything new has turned up since this thread was posted in 2013.
I just googled it and no, just the final version of the paper (which I have not read tbh).
ETA: find it here0 -
This is a master's thesis, and not a study published in a peer-reviewed medical journal. That being said, it's always a bad idea when people eat ad libitum. That never ends well.
I follow a Paleo style of eating, but still monitor calories and macronutrients. I eat 3-4 ounces of meat, chicken or fish for lunch and dinner, two eggs a day, and use fats and oils by the teaspoon. I eat a half-ounce of nuts at a time maybe one or twice a week. The rest--fruits, veggies, sweet potatoes, a quarter-cup of yogurt a day, lots and lots of berries. And, being small, middle-aged, and inactive except for 45 minutes of cardio a day, I stay at 1200 calories. Haven't had any white flour since January 1. I think beans are a healthy food, so I will eat them from time to time.
I guess all this is to say that it may be that the real issue with "eating Paleo" might be the portion sizes, at least in this paper, and perhaps even in general.
I might submit this to that prestigious medical journal named Duh.0 -
thecakelocker wrote: »
Indeed. A PE dept masters thesis.
It's data. Sure. And folks will cherry pick it like there's no tomorrow.
Until the next (hopefully peer reviewed) study comes along.
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How do people even find nearly 2 year old threads to comment on? If it's a terribly niche topic where the last relevant thread on it was quite some time ago then I could understand it, but I'm preeeeeetty sure there have been one or two threads on Paleo since May of 2013. How does one make the decision that THIS is the thread to bump? Or, how do you not notice the date created? I'm not being snarky at all, I'm just constantly genuinely fascinated by zombie threads and am truly curious.0
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This is a master's thesis, and not a study published in a peer-reviewed medical journal. That being said, it's always a bad idea when people eat ad libitum. That never ends well.
I follow a Paleo style of eating, but still monitor calories and macronutrients. I eat 3-4 ounces of meat, chicken or fish for lunch and dinner, two eggs a day, and use fats and oils by the teaspoon. I eat a half-ounce of nuts at a time maybe one or twice a week. The rest--fruits, veggies, sweet potatoes, a quarter-cup of yogurt a day, lots and lots of berries. And, being small, middle-aged, and inactive except for 45 minutes of cardio a day, I stay at 1200 calories. Haven't had any white flour since January 1. I think beans are a healthy food, so I will eat them from time to time.
I guess all this is to say that it may be that the real issue with "eating Paleo" might be the portion sizes, at least in this paper, and perhaps even in general.
I might submit this to that prestigious medical journal named Duh.
Well, let's see. I eat a few grams of nuts once or twice a week. I freely eat yogurt, berries, veggies, sweet potatoes, two eggs a day, and think beans are a great, healthy food. I, too, stay at 1200 calories. I'm older and short.
I haven't had white flour since September, 1997. Heck, I haven't had wheat since then.
Can I be paleo?
I'm a vegetarian, btw. Your diet just sounds like normal, balanced nutrition comprised of yummy food.
I'm not sure what my point is, other than the vagueness of the "paleo" label.
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How do people even find nearly 2 year old threads to comment on? If it's a terribly niche topic where the last relevant thread on it was quite some time ago then I could understand it, but I'm preeeeeetty sure there have been one or two threads on Paleo since May of 2013. How does one make the decision that THIS is the thread to bump? Or, how do you not notice the date created? I'm not being snarky at all, I'm just constantly genuinely fascinated by zombie threads and am truly curious.
Lord. Why WAS this bumped? Thanks. Wish I'd noticed before I bothered replying.0 -
How do people even find nearly 2 year old threads to comment on? If it's a terribly niche topic where the last relevant thread on it was quite some time ago then I could understand it, but I'm preeeeeetty sure there have been one or two threads on Paleo since May of 2013. How does one make the decision that THIS is the thread to bump? Or, how do you not notice the date created? I'm not being snarky at all, I'm just constantly genuinely fascinated by zombie threads and am truly curious.
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And, you know, thinking more about this, a Mediterranean-style way of eating may well be superior--it's been studied rigorously and meat is used as a condiment rather than as the main attraction of meals. There's even a Mediterranean Diet pyramid, which makes it clear that there ain't no eating ad libitum without consequences.
When I got here, I identified as Paleo, but because I know a bit about nutrition, I took what made sense and didn't do what didn't make sense to me. Beans? Healthy food. Me eat. Dairy? A bit here and there. Meat? Sure, but I'm not Fred Flintstone. I still avoid cheese and white flour, but more because I love them and do better leaving them alone than limiting my consumption.
One thing I have realized, that Paleo brought home to me in a huge way--I don't feel good when I eat processed food, so I don't eat it, unless it's a special occasion, and even then I limit my portions.
So maybe I don't "eat Paleo." Not sure, and I guess it doesn't matter. I just eat what makes my body feel good. But it was Paleo that got me thinking seriously about eating mostly whole, natural food. I miss chips and sweets at times, but I value feeling slimmer, healthier, and more energized more than I value those foods.
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This is a two year old thread?
*kitten*.
*Hangs head, walks away*0 -
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Perhaps the reason a two year old thread came up so readily is because every thread with the mere mention of Paleo has been removed.
Paleo suits me because of the elimination of grains and processed food. My body does not feel good when I eat them and it is as simple as that. I try to eat as close to nature as possible and Paleo gives me guidelines I can follow. You are not doing Paleo unless you are eating heaps of vegetables and the Paleo recipes inspire me.
Yep walking away from this 2 year old thread as well and wondering why I got sucked in to begin with.0 -
How do people even find nearly 2 year old threads to comment on? If it's a terribly niche topic where the last relevant thread on it was quite some time ago then I could understand it, but I'm preeeeeetty sure there have been one or two threads on Paleo since May of 2013. How does one make the decision that THIS is the thread to bump? Or, how do you not notice the date created? I'm not being snarky at all, I'm just constantly genuinely fascinated by zombie threads and am truly curious.
I wonder about that too. I can't figure out how to use the search function to find threads I want (or groups, sigh), so it's so funny when people decide to drag out some 2-3 year old thread.0 -
So maybe I don't "eat Paleo." Not sure, and I guess it doesn't matter. I just eat what makes my body feel good. But it was Paleo that got me thinking seriously about eating mostly whole, natural food. I miss chips and sweets at times, but I value feeling slimmer, healthier, and more energized more than I value those foods.
Honestly, I'm coming around a little on the named diet thing. I still don't really like them, but it seems that to some extent people may get excited about improving their overall way of eating because of them and if it helps them, great. Most people I know who are "paleo" in actual fact eat pretty similar to me since they don't really follow it that closely, but they do get excited about eating more veggies or more parts of the animal or source animals differently because of it, and I think those are good things, as is cooking. It occasionally annoys me that people claim a special name for what just seems to me to be healthy eating, but so be it.
(This has nothing to do with the study, obviously, but eh.)
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lemurcat12 wrote: »How do people even find nearly 2 year old threads to comment on? If it's a terribly niche topic where the last relevant thread on it was quite some time ago then I could understand it, but I'm preeeeeetty sure there have been one or two threads on Paleo since May of 2013. How does one make the decision that THIS is the thread to bump? Or, how do you not notice the date created? I'm not being snarky at all, I'm just constantly genuinely fascinated by zombie threads and am truly curious.
I wonder about that too. I can't figure out how to use the search function to find threads I want (or groups, sigh), so it's so funny when people decide to drag out some 2-3 year old thread.
From google, put in your search terms, then follow it with this: site:community.myfitnesspal.com/en/discussion/
You can also use the search tools option to narrow it down by date.
(this works with any site that has a bad search function, just replace the part after site: with whatever website you're trying to find something)0 -
Apparently a new person who came here and wanted their first post to be about Paleo bumped this to share their terrific blood work. To be accurate, the study did say these were otherwise healthy people whose blood levels worsened, but the person who bumped this said they had very poor blood results before starting this elimination diet.lemurcat12 wrote: »How do people even find nearly 2 year old threads to comment on? If it's a terribly niche topic where the last relevant thread on it was quite some time ago then I could understand it, but I'm preeeeeetty sure there have been one or two threads on Paleo since May of 2013. How does one make the decision that THIS is the thread to bump? Or, how do you not notice the date created? I'm not being snarky at all, I'm just constantly genuinely fascinated by zombie threads and am truly curious.
I wonder about that too. I can't figure out how to use the search function to find threads I want (or groups, sigh), so it's so funny when people decide to drag out some 2-3 year old thread.
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And, you know, thinking more about this, a Mediterranean-style way of eating may well be superior--it's been studied rigorously and meat is used as a condiment rather than as the main attraction of meals. There's even a Mediterranean Diet pyramid, which makes it clear that there ain't no eating ad libitum without consequences.
When I got here, I identified as Paleo, but because I know a bit about nutrition, I took what made sense and didn't do what didn't make sense to me. Beans? Healthy food. Me eat. Dairy? A bit here and there. Meat? Sure, but I'm not Fred Flintstone. I still avoid cheese and white flour, but more because I love them and do better leaving them alone than limiting my consumption.
One thing I have realized, that Paleo brought home to me in a huge way--I don't feel good when I eat processed food, so I don't eat it, unless it's a special occasion, and even then I limit my portions.
So maybe I don't "eat Paleo." Not sure, and I guess it doesn't matter. I just eat what makes my body feel good. But it was Paleo that got me thinking seriously about eating mostly whole, natural food. I miss chips and sweets at times, but I value feeling slimmer, healthier, and more energized more than I value those foods.
Good point. I eat what makes me feel good physically and mentally. Most of the time, to feel good physically, I need whole foods, including whole grains. Sometimes mentally to feel good I need things that aren't considered intrinsically healthy, like chips/sweets, including the full-fat, full-sugar versions, though I am developing more and more alternatives along the way. Moderation yes. Elimination- nah, not for me.0 -
lemurcat12 wrote: »So maybe I don't "eat Paleo." Not sure, and I guess it doesn't matter. I just eat what makes my body feel good. But it was Paleo that got me thinking seriously about eating mostly whole, natural food. I miss chips and sweets at times, but I value feeling slimmer, healthier, and more energized more than I value those foods.
Honestly, I'm coming around a little on the named diet thing. I still don't really like them, but it seems that to some extent people may get excited about improving their overall way of eating because of them and if it helps them, great. Most people I know who are "paleo" in actual fact eat pretty similar to me since they don't really follow it that closely, but they do get excited about eating more veggies or more parts of the animal or source animals differently because of it, and I think those are good things, as is cooking. It occasionally annoys me that people claim a special name for what just seems to me to be healthy eating, but so be it.
(This has nothing to do with the study, obviously, but eh.)
He he I knew we were kindred spirits.0 -
lemurcat12 wrote: »How do people even find nearly 2 year old threads to comment on? If it's a terribly niche topic where the last relevant thread on it was quite some time ago then I could understand it, but I'm preeeeeetty sure there have been one or two threads on Paleo since May of 2013. How does one make the decision that THIS is the thread to bump? Or, how do you not notice the date created? I'm not being snarky at all, I'm just constantly genuinely fascinated by zombie threads and am truly curious.
I wonder about that too. I can't figure out how to use the search function to find threads I want (or groups, sigh), so it's so funny when people decide to drag out some 2-3 year old thread.
From google, put in your search terms, then follow it with this: site:community.myfitnesspal.com/en/discussion/
You can also use the search tools option to narrow it down by date.
(this works with any site that has a bad search function, just replace the part after site: with whatever website you're trying to find something)
Thanks! (It would be more convenient if you could do it from here, of course, but I guess you can't ask for everything.) ;-)
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mamapeach910 wrote: »
Can I be paleo?
I'm a vegetarian, btw. Your diet just sounds like normal, balanced nutrition comprised of yummy food.
I'm not sure what my point is, other than the vagueness of the "paleo" label.
Do you think that, for instance, the Mediterraen diet is less vague?
Paleo is a large template, and yes there are vegetarians who claim to be paleo.
Of course if you don't find reasonable the paleo hypothesis (i.e.: there are certain foods we haven't still genetically fully adapted), your aren't paleo.
Yes the hypothesis could be wrong, but I can't see why there are people people who insist to call it a "fad", while the PUBLISHED literature shows that it is very healthy.
Here is a recent study:
http://www.lipidworld.com/content/13/1/160
Not bad for a fad, right?0
This discussion has been closed.
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