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I am on Contrave, and have been for about three months. It took 5 or 6 weeks for it to kick in, but have manage to lose about 17 pounds in about 6 weeks. Thanksgiving really set me back. The next day, I had gained almost 4 pounds and it took me 3 days to get back to where I was the day before Thanksgiving.

Regarding Contrave. It does not eliminate the need for self-discipline and will power. It is still hard, but for me, it makes it possible to make wise choices.