I recently had some gastro issues at 32. Through going to the doctor for this issue it was suggested by the specialist to stop taking omeprazole/nexium/Prilosec because it was more than likely the root cause of my ulcerative colitis. I have had an acid reflux problem for ten years and had taken the pills everyday for that long. I sort of didn't believe the doctor so I did what most do and read up on it online. To my surprise not only was it very likely the cause but I also found something else interesting. Omeprazole causes gradual weight gain and makes it very difficult for people to lose excess weight. I had gained roughly 50lbs over the course of ten years and though I lift heavy weights three days a week and did cardio five days a week I wouldn't lose more than a five to ten pounds over the course of three months. I stopped taking this pill and not only is my acid reflux very manageable by avoiding certain foods but I have lost 9lbs in 17 days from doing exactly the same thing I've always done. The only difference is the pill.