Getting comfortable losing weight

I'm not sure I understand what you're asking. I assume you want to lose weight. What is it about making progress toward your goal that makes you uncomfortable? (Not trying to be snarky or even Socratic. While I could try guessing what the issue is, it seems more efficient if you just tell us.)

What makes you feel uncomfortable about it? If you share the specifics, you may get more useful answers.

Don't restrict yourself too much by eating too little calories in order to lose as fast as possible
Don't eliminate foods, just work on portion control
Log your food before you eat it so you know how many calories your about to eat and you can adjust those calories

Plug your info into MFP accurately to get your calorie goal
Eat back your exercise calories (or at least 50% of them)

If you have 75+ lbs to lose 2 lbs/week is ideal,
If you have 40-75 lbs to lose 1.5 lbs/week is ideal,
If you have 25-40 lbs to lose 1 lbs/week is ideal,
If you have 15 -25 lbs to lose 0.5 to 1.0 lbs/week is ideal, and
If you have less than 15 lbs to lose 0.5 lbs/week is ideal.

Maybe focus on behaviour goals and what makes you feel your best rather than focussing on specific weight goals. Such as focussing on eating when sitting down, without distraction, eating slowly and really noticing the food you're eating (as opposed to randomly grabbing food on the fly, eating mindlessly or while preparing food in the kitchen, scarfing down food late at night while watching tv), trying to focus on the quality of your food, such as having veggies with meals and so on, getting to bed on time and optimizing sleep, getting some form of movement every day. Focussing on implementing healthy habits and behaviours and focussing on what makes you feel good and healthy may be less frightening and more approachable than focussing on your weight and body image from the get go. If you feel like you self sabotage your weight loss efforts because you are scared of losing your "protective pounds" maybe don't focus on the pounds and focus on the health enhancing habits instead. It's just a thought. Potentially also having a support system and someone to talk to about your fears and apprehensions might help.