Nonalcoholic Fatty Liver causes

It IS scary!

@moniquelhoward - good on you for reversing!

@routheles1 - did they suggest any changes to food? Change meds?

there are actually many NIH studies regarding corn syrup and fatty liver. A study suggested that consuming high amounts of fructose may promote non-alcoholic fatty liver disease by damaging the intestinal barrier.

NIH:

https://www.nih.gov/news-events/nih-research-matters/how-high-fructose-intake-may-trigger-fatty-liver-disease

Endocrine Society:

https://www.endocrine.org/news-and-advocacy/news-room/2022/people-who-consume-too-much-high-fructose-corn-syrup-could-be-at-risk-for-nafld

NIH/ National Institute of Diabetes
https://www.niddk.nih.gov/news/archive/2020/how-high-fructose-intake-trigger-fatty-liver-disease

Harvard Health Study:

https://www.health.harvard.edu/heart-health/abundance-of-fructose-not-good-for-the-liver-heart#:~:text=From%20fructose%20to%20fat,who%20drink%20too%20much%20alcohol.

it’s really not a debate that it’s not ideal for optimal liver health.

Fructose contributes to both liver fat and body fat, but the liver itself is the first to suffer, but to be clear, it's also excess calories and fructose intake together, and because the liver is the primary site of fructose metabolism where it converts that fructose into fatty acids and bears the brunt of the biochemical consequences that contribute to NAFLD.

Also and as it relates to our intestinal barrier from the formation of NAFLD from that excess fructose it produces inflammatory signals and altered bile acids that can disrupt the gut microbiota and weaken the intestinal barrier and basically causes small breaches in the lining and contributes to increased intestinal permeability, which contribute to endotoxins from our gut bacteria (microbiome) to enter the bloodstream and reach the liver, triggering further inflammation and damage and if nothing is done then the cycle repeats itself and escalates, not a good thing. Most of this bad stuff is really associated with a poor diet, mostly high in processed and UPF and when consumed in excess, but NAFLD can still take place in the absence of excess calories as well, just not to that extent or as quick, but it does happen. Get your CRP levels checked if your concerned and there's a few other tests as well like ferritin, ESR, NLR and Interleukin-6 (IL-6) and TNF-alpha, which are probably added costs.

Find a different doctor. Fatty liver without alcohol consumption is "non alcoholic steatohepatitis" (non alcoholic fatty liver disease. It's usually related to obesity and overeating.

My nephew had elevated enzymes and was diagnosed with fatty liver disease with no reason such as drinking alcohol his dr told him it was from the Covid shot and there's quite a few cases… I'm wondering now if that's the case with myself as well.

Where did you get the information that there are quite a few cases caused by Covid shot??

If a Dr told your nephew that, without any evidence t o support such a sweeping statement, then that sounds very poor medical advice - o n the other hand unless yo u were actually i n the appt and heard the doctor say it - it may not have been exactly what was said.

Non alcoholic fatty liver disease has been around long before covid or covid vaccines - highly likely the cause is a combination of one or more of smoking, lack of excercise, weight, diet, genetics.

I agree with most of what you said but don't agree with the hereditary hypothesis/theory aspect. All humans have a predisposition but we don inherit the disease. For example the prevalence of diabetes in the 1930's and 40's was around 0.5% of the adult population in the US, with a larger percentage living rural. Today diabetes in the same population is about 11.5%.

Type 1 Diabetes has a genetic component, but it’s also autoimmune. Even with a family history, it’s relatively rare unless specific genes are triggered by environmental factors.

Type 2 diabetes in 1980 in the US according to the CDC effected just under 6 million or about 2% of the population, today it's 53 million which is an increase of 783% and the explosion in cases is overwhelmingly driven by environmental and lifestyle changes, not genetics. Our predisposition for diabetes was there in 1980—but the triggers weren’t nearly as widespread.

I believe if someone holds some aptitude for critical thinking I suspect it should be quite obvious why this change has occurred and personally I'm not going to blame my grandparents or parents for my prediabetes but my change in those environmental and lifestyle that have put my prediabetes into remission for the last dozen years. imo of course. Cheers.

TLDR: diabetes 2 in 1980 was rare, so don't blame your grandparents.

Well, almost all humans have a predisposition to an insulin reaction that is then elevated by environmental factors to meet the criteria which represents insulin resistance and prediabetes. There’s compelling paleoanthropological and evolutionary evidence suggesting that humans have a built-in predisposition for insulin resistance and fat storage, basically the bodies evolutionary safeguard to starvation which under modern conditions can manifest as diabetes, so yeah there is a genetic marker involved.

Also hyperinsulinemia without high blood sugar levels (aka Hidden Insulin Resistance) and doesn't register in a blood test at all represents over 40% of the US population according to a study by using NHANES data and right now almost 70% of the population show signs of insulin resistance, prediabetes, diabetes, hyperinsulinemia, or impaired glucose metabolism. Most of the US population are metabolically dysfunctional which will include elevated triglycerides, low HDL, high blood pressure and central obesity, aka visceral fat and it's pretty obvious when we look at videos of regular populations during the 50's and 60's in US cities which are available all over the internet and you tube.

2 people consuming the same diet and being the same weight is complicated but metabolic health is influenced far more than just calories and body size. we just can't control humans for any length a time to ensure every single aspect of their lives and I mean every single aspect of their lives is "exactly" the same so a comparison can actually be done, and why we need to rely on more of the hard sciences, which is exactly what we were talking about for the most part, so thanks for that. cheers.