Has anyone used GPL-1 shots? What was your experience? Side effects?

I tried ozempic years ago and I didn’t really get any side effects except mild nausea at first. The problem was I didn’t lose any weight! I exercised and watched my calories but couldn’t make it happen. It doesn’t work for everybody.

my Dr wants me to try ZepBound, but I have marketplace insurance and it’s not covered.

I have been on Mounjaro since mid June and I have lost 26 lbs. I used to get migraines and haven't had one since starting it. I also have PCOS and find it helps with the blood sugar sensitivity that can go along with that. I had some mild nausea for a few hours the first 2 days after my shot and some constipation occurred after being on it for around a month. The constipation clears up with taking magnesium at bed time. I haven't gone past the 2.5 mg as I am still losing weight just at a very slow rate, which is what I prefer.

I started on tirzepatide back in March and have lost 24lbs in that time altogether. I am still on a low dose though but it has helped my cravings A LOT!! I also had gastric bypass surgery 2 and a half years ago and was at a stall for 6 months so decided to give the GLP-1's a try. The process has been slow, but they as the saying goes, slow and steady wins the race!

I have been taking Ozempic since December 2024 and have lost 45 pounds. I started at .25 milligram and increased to .50 milligram. The last couple of months I haven't felt the same effect from the drug as I did in the beginning so I think my body has gotten used to it. I do have stomach issues on a regular basis so I didn't notice Ozempic being a problem for me. No nausea. It curbed my alcohol consumption for red wine, bloody marys, heavy/thick consistencies, etc. I did feel fatigued but not anymore. I actually think it helped with minimizing post-menopause symptoms. When I do have cravings, I will have a small amount of what I want and it seems to resolve itself. Its important to drink alot of fluids as I did get dehydrated in one month and had kidney stone(s). I can say that its been VERY helpful to have myfitnesspal on this weight loss journey with Ozempic in order to keep me mindful of my calorie intake, water intake, exercise, etc.

https://community.myfitnesspal.com/en/profile/1011935435/Letsgetfit_83 when did you start losing weight on Ozempic?

I am on a compounded tirzepatide with B-12 since Aug 28th, and have lost about 16 lbs and over 20 inches. I have had zero side effects so far. I had found that I do my injection before I go to bed, then I sleep off any potential issues! I also strength train 5 x a week plus get my steps in everyday. Also, focus on protein and healthy fats, and veggies. Make sure to get your fiber in as well since GLP-1s slow down our digestion/ motility. Also, making sure to stay hydrated and get electrolytes in. This medication kind of turns off the sense of needing food or drink so using MyFitness Pal has made a difference of helping keep track of everything. I also take supplements to make sure I am “filling in the gaps” of any nutritional needs. I also do Intermittent Fasting.. so easy to do and the GLP-1 helps tremendously with this.
This medication has definitely helped with inflammation, food noise, and sleep.

It is not a magic fix, BUT definitely worth using as another tool to achieve long-lasting lifestyle changes.

I’ve heard it doing good things but scientifically I don’t think doctors are informing the population on how to properly use and WHAT to do while using it. For example, a person 100% needs to be working out. There’s major lawsuits coming

pure weightloss shouldnt be the goal. Fatloss should be the goal. Working out when calories are low is more about maintaining muscle mass. Fast weightloss combined with low protein and no working out is bad combo unless you're obese then the working out becomes less important

I don't know if something specific to the glp-1 drugs triggers additional concern and warnings; but, in general, anytime you achieve a larger deficit and faster weight loss the optimum retention of non fat = lean = (by extension) muscle mass enters into the picture.

What is most beneficial for each of us (i.e. individually optimal) does vary according to our individual starting points & health concerns.

please read what I posted. I did not say people need to work out to loose weight 🤦‍♀️

there’s also other things in my post that should be combined. I wrote it like that for a reason

okay, it’s the internet so I guess take it however you want 🤷‍♀️

Tom, where did you get the retatrutide? Isn’t that still in research?

I actually will be starting it next Thursday. My insurance FINALLY just approved it after close to 2 months of back and forth with my doctor. I will say, this was not an easy decision on my part either, but my health is deteriorating to a point where I NEED to do something and I NEED help. I have multiple chronic health and pain issues that are made worse by my weight. I am working with my PCP, a NP that is specialized in these meds and weight loss in general, a therapist who is helping me with my mental health struggles around food, AND a physical therapist who is also helping me come up with exercises I can do that doesn't flare my issues.