Has anyone used GPL-1 shots? What was your experience? Side effects?

Hi, I’m contemplating using GPL-1 shots. But I’m afraid of the side effects. Does anyone have any recommendations?
Thank you
Answers
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I tried ozempic years ago and I didn’t really get any side effects except mild nausea at first. The problem was I didn’t lose any weight! I exercised and watched my calories but couldn’t make it happen. It doesn’t work for everybody.
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I’ve been taking Zepbound (tirzepatide) since the end of May. Side effects have been minimal - occasional constipation, and sometimes nausea if I eat more than I should at one time. The most side effects I ever felt was when increasing dose, but once my body got used to the new dose, it got better.
Otherwise, I feel great and have lost 44 pounds.
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my Dr wants me to try ZepBound, but I have marketplace insurance and it’s not covered.
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I use Retatrutide its a glp3 so is more effective than glp1. Works great. With any glp peptide you want to use the lowest dosage that allows you to hit your calorie goals. Use it 3 times a week to eliminate any side effects. Small, high protein meals and no eating 3 hours before bed. Yes, there are tricks to it however the results are there.
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I have been on Mounjaro since mid June and I have lost 26 lbs. I used to get migraines and haven't had one since starting it. I also have PCOS and find it helps with the blood sugar sensitivity that can go along with that. I had some mild nausea for a few hours the first 2 days after my shot and some constipation occurred after being on it for around a month. The constipation clears up with taking magnesium at bed time. I haven't gone past the 2.5 mg as I am still losing weight just at a very slow rate, which is what I prefer.
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I got up to full dosage on Wegovy (semiglutide) and then Zepbound (trizepatide). Neither worked for me. I didn't get any side effects but I also didn't get any benefit. It's really frustrating to see so many people have success with these drugs when they do nothing for me. I guess I'm just a non-responder.
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I started on tirzepatide back in March and have lost 24lbs in that time altogether. I am still on a low dose though but it has helped my cravings A LOT!! I also had gastric bypass surgery 2 and a half years ago and was at a stall for 6 months so decided to give the GLP-1's a try. The process has been slow, but they as the saying goes, slow and steady wins the race!
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Thats the best way to do it, just enough to hit your calorie goal without hunger and curb cravings. That will be not taking a full weekly dose at once, divide by 3 a week otherwise its not an even level of effects.
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I have been taking Ozempic since December 2024 and have lost 45 pounds. I started at .25 milligram and increased to .50 milligram. The last couple of months I haven't felt the same effect from the drug as I did in the beginning so I think my body has gotten used to it. I do have stomach issues on a regular basis so I didn't notice Ozempic being a problem for me. No nausea. It curbed my alcohol consumption for red wine, bloody marys, heavy/thick consistencies, etc. I did feel fatigued but not anymore. I actually think it helped with minimizing post-menopause symptoms. When I do have cravings, I will have a small amount of what I want and it seems to resolve itself. Its important to drink alot of fluids as I did get dehydrated in one month and had kidney stone(s). I can say that its been VERY helpful to have myfitnesspal on this weight loss journey with Ozempic in order to keep me mindful of my calorie intake, water intake, exercise, etc.
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