Fat Cell Death: Broscience or Science?

2»

Replies

  • Iwishyouwell
    Iwishyouwell Posts: 1,888 Member
    edited December 2014
    But more leptin would also mean more signal to the brain, which might be a desirable outcome for those who have trouble feeling full?

    Which makes me wonder if the point will be to chemically assist with the receptors in order to take advantage of the higher leptin in overweight people.

    Though that still doesn't deal with the non-hunger related eating component. I wonder how many people are largely overweight not because hunger drives them to overeat, but because they simply eat for many reasons, almost none of them having to do with true hunger.

  • keefmac
    keefmac Posts: 313 Member
    Read these boards daily and you'll find a multitude of reasons for overeating, if they have the "woe is me" attitude they will not change their eating habits for more than a week or two.

    There's always something to blame for being overweight.
  • This content has been removed.
  • Iwishyouwell
    Iwishyouwell Posts: 1,888 Member
    keefmac wrote: »
    Read these boards daily and you'll find a multitude of reasons for overeating, if they have the "woe is me" attitude they will not change their eating habits for more than a week or two.

    There's always something to blame for being overweight.

    Well yes.

    Which begs the question as whether even a truly effective weight loss drug would make a major dent in the obesity epidemic considering that overconsumption is tied to a lot more factors than just physiological hunger.

    MrM27 wrote: »
    Look at how when things get into actual science you don't have endless drones popping in.

    Yep

    crickets.gif
  • vgnfarmer
    vgnfarmer Posts: 108 Member
    I did quick PubMed search and found some studies on mice that show adipose apoptosis can happen. There is current (2014) research on it but seems to be complicated and as of yet not fully understood...At any rate i'm going to try sticking with calorie deficit to lose and fingers crossed that some of those fat cells die! Ben Greenfield had a lady on one of his podcasts who talked about it too but I think she said most of the time we have too much inflamation for it to happen? idk
  • ukaryote
    ukaryote Posts: 850 Member
    mccindy72 wrote: »
    Also, the body's fat cells have an unlimited capacity for storing fat - especially the cells of the abdomen, as we've seen in recent years.
    Amazing. The body is just incredible.

    Combine that with liposuction where the remaining cells fill out to compensate for the removed cells, and you can end up with a really strange body shape.

  • Wheelhouse15
    Wheelhouse15 Posts: 5,575 Member
    ukaryote wrote: »
    mccindy72 wrote: »
    Also, the body's fat cells have an unlimited capacity for storing fat - especially the cells of the abdomen, as we've seen in recent years.
    Amazing. The body is just incredible.

    Combine that with liposuction where the remaining cells fill out to compensate for the removed cells, and you can end up with a really strange body shape.

    The body is amazing but certainly does have limits. If it was a little better adapted to our current nutritional environment it would probably have pathways to greatly limit or even completely shut down new fat storage. Of course, our heritage is one of surviving through food scarcity and famines so we really haven't had any reason to limit energy storage.

  • chouflour
    chouflour Posts: 193 Member
    It looks like there's a potential method developed in Israel - just waiting for research dollars.

    http://www.tasmc.org.il/sites/en/Research/Tech-Transfer/Pages/technologies-pharma.aspx#p4
  • FaylinaMeir
    FaylinaMeir Posts: 661 Member
    Can I just pop in and say I keep reading Adipose and I'm thinking doctor who LOL

    SNF05TVBIZ1_464343a.jpg
  • GaleHawkins
    GaleHawkins Posts: 8,159 Member
    MrM27 wrote: »
    I've done a ton of reading on cell hypertrophy, hyperplasia and death. I've not seen any evidence that fat cells die off.

    I agree.

  • This content has been removed.
  • keefmac
    keefmac Posts: 313 Member
    keefmac wrote: »
    Read these boards daily and you'll find a multitude of reasons for overeating, if they have the "woe is me" attitude they will not change their eating habits for more than a week or two.

    There's always something to blame for being overweight.
    keefmac wrote: »
    Read these boards daily and you'll find a multitude of reasons for overeating, if they have the "woe is me" attitude they will not change their eating habits for more than a week or two.

    There's always something to blame for being overweight.

    Well yes.

    Which begs the question as whether even a truly effective weight loss drug would make a major dent in the obesity epidemic considering that overconsumption is tied to a lot more factors than just physiological hunger.

    MrM27 wrote: »
    Look at how when things get into actual science you don't have endless drones popping in.

    Yep

    crickets.gif

    If people decide to cheat even after gastric bands I don't think there is any pill that will cure everybody!.
  • Iwishyouwell
    Iwishyouwell Posts: 1,888 Member
    Can I just pop in and say I keep reading Adipose and I'm thinking doctor who LOL

    SNF05TVBIZ1_464343a.jpg

    Perhaps I should be watching Doctor Who...
  • dbmata
    dbmata Posts: 12,950 Member
    ukaryote wrote: »
    mccindy72 wrote: »
    Also, the body's fat cells have an unlimited capacity for storing fat - especially the cells of the abdomen, as we've seen in recent years.
    Amazing. The body is just incredible.

    Combine that with liposuction where the remaining cells fill out to compensate for the removed cells, and you can end up with a really strange body shape.
    I was going to ask this.

    Why wouldn't slicing these cells out when obese be effective long term. Remaining cells will just fill out more.
This discussion has been closed.