Anti-Depressants- How I Gained My Weight

2April

Antidepressants are just a bandaid for the problem. All that crap is not good for you. Suck it up.

Depression is a imbalance in the brain. Just as you'd give medicine to someone with cancer you'd give it to someone with depression. It's not that easy.

The chemical imbalance theory has never been proven...it was made up for marketing purposes.

ryansgram

I have been taking celexa for 6 months and i am losing weight.

BeautyFromPain

My advice, you don't have to take it or agree with it, try to change your life without taking these drugs unless you absolutely have to. This is one of those cure is worse than the disease situations.

I agree. I think taking it for a short time is ok, but try and get off it as soon as possible. Side affects are horrible. Good luck!

If you have ever been TRULY depressed, you wouldn't say things like "go off your meds" so lightly. For some people, not being on their meds is a death sentence! This really is an area where if you are not qualified and don't have their personal medical records in your hands, you probably should not being saying such things because "someone" out there may take your advice and end up dead. I wouldn't want that on my shoulders!

After my sister was murdered, it took a month to find the body. Afterwards I locked myself in the basement for a long time and used empty pop bottles to pee in, so believe me, I know what it's like to be truly depressed and I do not take it lightly.

I'm sorry about your sister.
I agree that antidepressants should be avoided. I can't believe doctors hand them out like candy and people take them like they are the missing piece of the puzzle. Depression and sadness are a NORMAL part of life. These drugs exist to make people money, not to make people feel better. I resent that they are being taken in such high numbers that they are found in our drinking water and are doing untold damage to marine life.

There is a difference between real depression and the depression you are obviously talking about. Depression as in feeling like you want to die every second of the day. With an imbalance in the brain. It is an illness like no other. Should they should giving chemo to cancer patients? No. So why should they stop giving antidepressants to people who legit NEED them. At one point in my life I was on them and although after I started exercising I became so much happier I was able to come off them, It is not that easy for some people.

bitty1taz

I have tried a many different meds in order to help with my anxieties. None worked. Either I was seeing things that were not there, or I couldn't wake up because they had me so zoned out, and I always gained weight. Needless to say I got fed up and went off the meds (with dr approval). I am currently learning to meditate, which so far is helping out. I have ADHD so this is something that is not easy for me, but it is helping and getting easier with time.
I'm also slowly cutting back my sugar intake...yet another thing that is really hard for me.
Hang in there and do what is best for you.

Michele_T

Wow, when I scanned the 4 pages of posts I didn't see anyone on here with an MD after their name.
My only thought on this post is-
Take up your medical issues with a professional.

jg627

My advice, you don't have to take it or agree with it, try to change your life without taking these drugs unless you absolutely have to. This is one of those cure is worse than the disease situations.

I agree. I think taking it for a short time is ok, but try and get off it as soon as possible. Side affects are horrible. Good luck!

If you have ever been TRULY depressed, you wouldn't say things like "go off your meds" so lightly. For some people, not being on their meds is a death sentence! This really is an area where if you are not qualified and don't have their personal medical records in your hands, you probably should not being saying such things because "someone" out there may take your advice and end up dead. I wouldn't want that on my shoulders!

After my sister was murdered, it took a month to find the body. Afterwards I locked myself in the basement for a long time and used empty pop bottles to pee in, so believe me, I know what it's like to be truly depressed and I do not take it lightly.

I'm sorry about your sister.
I agree that antidepressants should be avoided. I can't believe doctors hand them out like candy and people take them like they are the missing piece of the puzzle. Depression and sadness are a NORMAL part of life. These drugs exist to make people money, not to make people feel better. I resent that they are being taken in such high numbers that they are found in our drinking water and are doing untold damage to marine life.

Please read and comment on the following article.

Yale J Biol Med. 2012 March; 85(1): 153–158.
Published online 2012 March 29.
PMCID: PMC3313530
Copyright ©2012, Yale Journal of Biology and Medicine
Antidepressants and Advertising: Psychopharmaceuticals in Crisis
Nathan P. Greenslit, PhDa* and Ted J. Kaptchukb
aHistory of Science Department, Harvard University, Cambridge, Massachusetts
bProgram in Placebo Studies, Beth Israel Deaconess Medical Center, Boston, Massachusetts
*To whom all correspondence should be addressed: Nathan P. Greenslit, PhD, Harvard University, History of Science Department, 1 Oxford Street, Cambridge, MA 02118; Email: npg@media.mit.edu.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License, which permits for noncommercial use, distribution, and reproduction in any digital medium, provided the original work is properly cited and is not altered in any way.
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Abstract
As the efficacy and science of psychopharmaceuticals has become increasingly uncertain, marketing of these drugs to both physicians and consumers continues to a central part of a multi-billion dollar per year industry in the United States. We explore how such drug marketing portrays idealized scientific relationships between psychopharmaceuticals and depression; how multiple stakeholders, including scientists, regulatory agencies, and patient advocacy groups, negotiate neurobiological explanations of mental illness; and how the placebo effect has become a critical issue in these debates, including the possible role of drug advertising to influence the placebo effect directly. We argue that if and how antidepressants “work” is not a straightforward objective question, but rather a larger social contest involving scientific debate, the political history of the pharmaceutical industry, cultural discourses surrounding the role of drugs in society, and the interpretive flexibility of personal experience.
Keywords: direct-to-consumer advertising, advertising, antidepressants, placebo effect
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Introduction
Psychopharmaceuticals are currently in crisis, and the science of depression has become a contest between scientists, pharmaceutical marketing, physicians, professional medical organizations, regulatory agencies, and patients. Public controversies and medical uncertainties concerning antidepressants have become the norm [1,2,3]. Since direct-to-consumer (DTC†) advertising was approved by the FDA in 1997 [4], pharmaceutical companies have been accused of exaggerating claims of drug efficacy [5], downplaying the health risks of antidepressant use [6,7,8], and hiding behind smokescreen public relations slogans of medical “awareness campaigns,” while slyly growing drug markets by over-medicalizing everyday experiences such as sadness, anxiety, and shyness [9,10]. In this controversial arena, the science of antidepressants has become uncertain, and physicians, policymakers, and consumers are left with few brute facts about if and how antidepressants work. Yet physicians want effective medicines, patients and policymakers want clarity of information, and pharmaceutical companies need to appear to be providing both. To provide a better understanding of the current predicament around psychopharmaceuticals, this article will look at three issues: 1) How pharmaceutical advertisements and professional marketing literature portray an idealized and simplistic relationship between medications and psychiatric illness; 2) how other stakeholders (patients, scientists, physicians, regulatory agencies, professional societies) accept or challenge a simple neurobiology of mental illness; and 3) how the placebo effect has become an increasingly important issue in these debates, including the new role of drug advertising to influence the placebo effect directly.
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Selling Science
Over the past decade, drug companies have launched extensive physician-directed and direct-to-consumer advertising campaigns to disseminate putative neuroscientific theories about mental illness. These ads are designed to convince doctors and patients that psychopharmaceuticals have an obvious, objective, and scientific relationship to the symptoms they are supposed to treat. Shortly after its FDA approval in 1987 [11], the first Prozac (fluoxetine) ads that appeared in medical journals claimed, “There is considerable evidence that serotonergic function may be reduced in the brains of depressed patients,” introducing Prozac as “a specifically-different antidepressant . . . Its distinctive chemistry means greater specificity.” The advertisement never claimed that Prozac would be any more efficacious than any other antidepressant. Rather, it focused on how the drug was chemically distinct from others, emphasizing that it had comparatively more specific action on neurochemical receptors. However, the rhetorical effect of using neuroscience in drug advertising is precisely to imply that pharmacological specificity translates into a more efficacious psychopharmaceutical. Since the original Prozac campaign, the medical image of psychopharmacological specificity has become increasingly fine-grained. A 2005 physician-directed ad for Remeron (mirtazapine) asked, “What’s the difference between SSRIs [selective serotonin reuptake inhibitors] and Remeron?” The answer: “SSRIs . . . Somewhat Selective; Remeron . . . Downright Picky. [Remeron offers] novel nonadrenergic and serotonergic pharmacological action.” This campaign capitalizes on the original “magic bullet” image of the SSRI, depicting how mirtazapine binds to a single subtype of the serotonin receptor. Just like the earlier Prozac ad, the Remeron ad does not promise greater efficacy, but rather more exact science.
Drug advertising seeks to fill in an explanatory gap between the bench science of psychopharmacology and the palpable or measurable real-world effects of antidepressants. While the pharmaceutical industry uses placebo-controlled clinical trials to establish that a given antidepressant is effective, these trials are neither designed nor intended to show why an antidepressant might work at all. Do patients experience symptom relief because their drug acts on a distinct underlying disease pathology (as pharmaceutical ads imply) or because their drug induces a psychoactive state (e.g., sedation, stimulation, or altered sense perception) [12]? There’s a lot at stake in deciding between these explanatory frameworks, since the science of mental illness and psychopharmaceuticals is contentious [13]. Not only do neuroscientists debate the most basic of biological mechanisms that may be involved in depression, but some recent analyses of clinical trial data suggest that, overall, SSRI antidepressants like Prozac and Effexor (venlafaxine) do not work much better than placebos [14,15,16]. Despite such broad uncertainty over both the scientific explanations and efficacy of antidepressants, DTC advertising is still a nearly 5 billion dollar per year industry (and practically unique to the United States, as no other country except New Zealand allows it) [17]. And antidepressants remain one of the most heavily advertised prescription drug categories [18].
Drug marketing gets recruited to do what science itself cannot: give meaning to scientific results. In an industry magazine editorial, one drug-marketing expert urged fellow marketers to “[t]ell the truth. Seriously, nothing sells like verisimilitude. Precise language and specific visuals, such as those that show the size of the pill, the mechanism of action or the genuine outcome of faithful compliance help create a reasonable semblance of ‘truth’” [19]. This marketer’s easy slippage from “truth” to “verisimilitude” to “reasonable semblance of truth” suggests that the very idea that neuroscience offers the truth of depression or anxiety is split between claims that the science is known and that it is unknown. In the middle is a rhetorical gray area of imputation, suggestion, and belief on the part of scientists, psychiatrists, and consumer-patients alike. In this middle comes the opportunity for companies to market the unknown to the Food and Drug Administration (FDA) and to the public, to repeat the possibility of neuroscience so that it becomes common sense.
The idea that neuroscience offers the “truth” of depression has gained remarkable popular culture cache in recent years, shaping our assumptions about the relationship between mind, body, and brain. One recent study concluded that neuroscience has a “seductive allure,” after showing that college students find theories of psychological phenomena more credible if they include neuroscientific terms, irrespective of whether neuroscience is actually relevant to the theories in question [20]. This finding resonates with how drug marketers reflect on their own advertising strategies: “Pharmaceutical companies need to realize that consumers do not care about your internal research. They do not ask for your drug because it is well researched. They ask because something you said in the 35 seconds made them interested. That is the end goal . . . Unfortunately, in the scientific world of drug companies, ‘I think’ is not allowed. ‘I know, I proved’ is the language rewarded” [21]. This quote comes from a 2002 article in the industry journal DTC Perspectives, published in the midst of the first DTC blitz. It warns that the drug advertisement development process should not mirror the drug development process. Since the advent of DTC, drug marketers have been honing how to give science market-driven meaning. Their professional literature encourages marketers to fantasize how to communicate to a market, before the drug is even developed: “This point is counter-intuitive to many companies. Doesn’t the science lead the way? Well, yes and no. Without the science, there is no product at all. But here’s what happens all too often with companies who overemphasize the science at the expense of the messages: they may develop very elegant answers to irrelevant questions” [22]. The article continues to explain how “market perceptions and needs” need to guide the science, not the other way around.
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A brief sociopolitical history of antidepressants
The science of psychopharmaceuticals is also contested by a variety of social groups, who fight over representations of neuroscience in advertising. On the one hand, patient advocacy groups have either embraced or resisted neuroscientific theories in drug advertising, depending on whether they interpret them as socially vindicating (biological explanations as exculpatory for stigmatized illnesses, such as premenstrual dysphoric disorder or post-traumatic stress disorder) or as socially constraining (biological explanations as oversimplified reductions of cultural or psychological complexity). On the other hand, advocacy groups, some including psychiatrists, have even filed complaints with the FDA and Federal Communications Commission (FCC), arguing that cartoons of SSRIs acting on neurochemical receptors (featured in Zoloft [sertraline] ads) are ultimately fraudulent claims about depression and its underlying biological pathology, because the science is still contentious. These controversies demonstrate what social scientists have observed concerning how seemingly objective things, like scientific fact, actually require a great deal of social work to be produced, circulated, and maintained.
Critiques over the neuroscience of antidepressants are caught up in larger sociomedical quandaries over what counts as proper medical uses of these drugs and how psychiatric illness should be defined and diagnosed in the first place. Early television commercials for Sarafem (fluoxetine hydrochloride, previously marketed as Prozac, which, at the time, had just gone off-patent) for premenstrual dysphoric disorder (PMDD) depicted frustrated women looking for lost car keys or trying to extract shopping carts at grocery stores. The FDA criticized these ads for not clearly distinguishing between PMDD and premenstrual syndrome (PMS) and for “trivializing the seriousness of PMDD.” The increased regulatory scrutiny over DTC has made pharmaceutical companies more strategic in how they tow the line. As one marketer put it: “Ad agencies have to be more creative than ever to create truly effective communications that are also responsible and do not overpromise” [23].
The current debates over the science, marketing, and uses of antidepressants are born out of a unique history of the role of drug therapy in psychiatric medicine [24]. Historically, American psychiatry has been at the center of broader social tensions between mainstream social institutions, countercultural movements, and civil rights. In the 1960s and 1970s, antipsychiatry groups challenged the cultural authority of organized medicine, especially psychiatry, arguing that it was an institution of social control. During this time, licit psychopharmaceuticals were vilified as “chemical straightjackets,” while illicit drugs that could only be obtained without a physician's blessing were celebrated as countercultural expressions of pleasure, mind expansion, and self-exploration, as epitomized by people like Ken Kesey and Timothy Leary. Benzodiazepines (such as Valium and Miltown) were the first psychiatric drugs to occupy a social middle ground between the two perceptions; they were prescription medications for the treatment of anxiety, but they were also pleasurable and consumed recreationally. But by the 1980s, prominent American media outlets, including The New York Times, were reporting that Valium was overprescribed and overconsumed and that people were becoming addicted to the drug. The sociomedical boundary of licit versus illicit got blurred in both directions.
Ever since the scandals surrounding the (mis)uses of benzodiazepines, the pharmaceutical industry has been deeply invested in the legal distinction between licit and illicit drugs, with its accompanying discourses of health and normality versus pleasure and dependency. One of the first DTC pamphlets for Prozac claimed that “Prozac doesn’t artificially alter your mood and it is not addictive. It can only make you feel more like yourself by treating the imbalance that causes depression.” Illicit versus licit; pleasure versus illness-healing; changing-self versus real-self: These are all distinctions that pharmaceutical marketing and its regulatory environment demand. But they also express social ambivalence over wanting drugs, yet fearing they will overstep medical, ethical, or philosophical boundaries to change a patient’s core personality or self.
The social ambivalence toward psychopharmaceuticals in the age of direct-to-consumer advertising takes the form of constant demand for more promises about the relationship between illness and science versus the equally difficult attempt to regulate those promises to conform to science. When Prozac first became commercially available in the late 1980s, it was not supposed to be inherently pleasurable, nor was it supposed to be addictive, and it was used for a widening range of depression and anxiety symptoms. With its growing use and popularization came new questions — no longer about the use of antidepressants to cope with everyday stress and anxiety, but about the use of antidepressants to shape one’s personality and identity. Peter Kramer famously articulated these questions in his 1993 book, Listening to Prozac [25]. In this bestseller, Kramer expressed a new willingness to use Prozac to tinker with his patients’ sense of self. Given the apparent safety of the drug, Kramer didn’t see this as medical bravado so much as a perfectly reasonable experiment made possible by the newest generation of psychopharmacology. He asked rhetorically about a typical encounter with one of his patients, “Who was I to withhold from her the bounties of science?”
In the last 15 years, such romanticized notions of SSRI antidepressants as safe opportunities to tweak a patient’s sense of self with the latest science have received greater public and regulatory scrutiny, from controversies over their questionable efficacy to dramatically reduced uses in children and adolescents to the possible increased risk of suicide from their use. And, as we have seen, the rudimentary science of psychopharmaceuticals has itself been more fundamentally critiqued.
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Science and symptoms
While there is no standard definition of “the placebo effect,” it is broadly used to designate symptom relief (e.g., pain, fatigue, anxiety, depression) that occurs due to such non-pharmacological components of a medical intervention as patient expectation or encouraging a supportive doctor-patient relationship [26]. The placebo effect has been especially troublesome for pharmaceutical companies trying to demonstrate the efficacy of antidepressants in clinical trials [14,15,27]. And yet, while this has led to the accusation that the drug industry promotes psychopharmaceuticals with questionable efficacy, the situation has become more complicated, as some drug marketers are now defending DTC advertising as a way to enhance the placebo effect, leading to better medication compliance: “[A]dvertising strategies [that depict obvious patient relief] not only create consumer demand for the advertised products, but may also create the emotionally conditioned responses and expectancies instrumental to enhancing a placebo effect that occurs when the medication is taken” [28].
Coincidentally or not, with the rise of DTC marketing, some argue that the placebo effect in depression has increased in recent years [29]. But given such efforts on the part of drug marketers to use advertising to bolster the placebo effect, it is striking that the clinical trial — which is what the FDA demands of pharmaceutical companies to connect their drugs to specific illness and prove that their drugs work as advertised — deliberately avoids accounting for marketing itself. Clinical trial participants are typically not told brand names of experimental drugs, and they are not shown advertisements that provide biological explanations of the drugs and depict symptom relief. On the contrary, drug companies worry about the placebo effect as a kind of psychological problematic that must be reduced, not enhanced, and they have gone so far as to screen out so-called “placebo responders” in sham “placebo washout” pre-trials, in which all participants are placed on a placebo antidepressant, and those who experience it as efficacious are discarded from the real clinical trial [30,31]. Here we see a profound disconnect between the protocol of a randomized double-blind control trial that attempts to isolate a drug’s real effect in the clinical trial, in part by removing any advertising messages, versus the attempt to actively generate and leverage the placebo effect through marketing.
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Conclusions
Psychopharmaceutical marketing participates directly in debates over what is scientifically known about mental illness, with important ramifications for doctor-patient interaction, and patient experiences with antidepressants. Right now, antidepressant advertising propagates narrowly biological explanations of depression (especially the seductive notion of simple neurochemical imbalance or deficiency) and leaves out any mention of how often symptom relief may occur because of non-pharmacological interventions. At the same time, it would seem that drug companies are using advertising precisely to inflate such non-pharmacological effects, with the goal of attracting consumers to antidepressants, and then keeping them on them. This disconnect between attempts to eliminate the placebo effect in the clinical trial versus attempts to bolster it through advertising indicates a severe tension in a society that privileges medicalized and scientific narratives about pharmaceuticals on the one hand, but which on the other hand is deeply ambivalent about understanding our relationship to psychotropic drugs. Indeed, if and how antidepressants work is not a straightforward objective question, but rather a larger social contest involving scientific debate, the political history of the pharmaceutical industry, cultural discourses surrounding the role of drugs in society, and the interpretive flexibility of personal experience. Therefore, we need to be open to interpretations of psychopharmaceutical action that acknowledge them as psychologically wily substances whose effects are both socially and pharmacologically determined. Drug advertising most certainly does not take these complexities into account, so it is currently in the hands of consumers and medical and policy decision-makers to do so.
Glossary
DTC direct-to-consumer
SSRI selective serotonin reuptake inhibitor
FDA Food and Drug Administration
FCC Federal Communications Commission
PMDD premenstrual dysphoric disorder

Footnotes
TK partially supported by grant # K24 AT004095 from NCCAM-NIH.
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References
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I couldn't agree more. This is why I drink well water.

bastins

Antidepressants are just a bandaid for the problem. All that crap is not good for you. Suck it up.

Yeah, sure, just "suck it up".

You're an idiot. Next time, keep your mouth shut until you know what you're talking about.

batalina

Wow, when I scanned the 4 pages of posts I didn't see anyone on here with an MD after their name.
My only thought on this post is-
Take up your medical issues with a professional.

you're right. something happened to me, but i am not qualified to speak as to my personal experience, as i am not a doctor. now i will refrain from having opinions about anything, such as if my dinner is going to taste good, because i am not a master chef, or that i suppose it might rain, judging by the look of these clouds, being that i am not a meteorologist.

AmerTunsi

There are two types of AD those that will cause you to lose some weight and the majority that will cause you to gain some weight. That was something I discussed with my Dr. and asked that she make sure not to put me on any medications that would cause me to gain weight - had plenty of that!

ALH1981

does anyone have the same problem with the herbal supplements? i tried 5htp for a while and igot extremely bloated and put on weight....?

AmerTunsi

I was on welbutrin for years and lost a bunch of weight. Just recently I stopped taking my anti depressants and gained 14lbs in a matter of minutes......lol, I am laughing but it was horrible. I am happy to be off of them, now I have to drop these 14lbs on top of my extra 20lbs..... But we are going to be this! My best,cat

Yep! This is the winner and the generic brandn also does the same thing.

2April

My advice, you don't have to take it or agree with it, try to change your life without taking these drugs unless you absolutely have to. This is one of those cure is worse than the disease situations.

I agree. I think taking it for a short time is ok, but try and get off it as soon as possible. Side affects are horrible. Good luck!

If you have ever been TRULY depressed, you wouldn't say things like "go off your meds" so lightly. For some people, not being on their meds is a death sentence! This really is an area where if you are not qualified and don't have their personal medical records in your hands, you probably should not being saying such things because "someone" out there may take your advice and end up dead. I wouldn't want that on my shoulders!

After my sister was murdered, it took a month to find the body. Afterwards I locked myself in the basement for a long time and used empty pop bottles to pee in, so believe me, I know what it's like to be truly depressed and I do not take it lightly.

I'm sorry about your sister.
I agree that antidepressants should be avoided. I can't believe doctors hand them out like candy and people take them like they are the missing piece of the puzzle. Depression and sadness are a NORMAL part of life. These drugs exist to make people money, not to make people feel better. I resent that they are being taken in such high numbers that they are found in our drinking water and are doing untold damage to marine life.

There is a difference between real depression and the depression you are obviously talking about. Depression as in feeling like you want to die every second of the day. With an imbalance in the brain. It is an illness like no other. Should they should giving chemo to cancer patients? No. So why should they stop giving antidepressants to people who legit NEED them. At one point in my life I was on them and although after I started exercising I became so much happier I was able to come off them, It is not that easy for some people.

Please read the article I posted. Nobody NEEDS antidepressants because they have not even proven to work better than placebo. I'm glad you feel better with exercise. Did you know studies have shown that exercise works better than antidepressants? Did you know that drug companies had knowledge that showed that antidepressants not only didn't work but also caused suicidal behaviors in young people and they tried to cover it up. I'm not saying that someone with depression doesn't need help, I am saying they don't need these pills.

Here is a snippet fro a 2004 news article:
GlaxoSmithKline PLC committed fraud by withholding negative information and misrepresenting data on prescribing its antidepressant Paxil to children, according to a lawsuit filed Wednesday by New York Attorney General Eliot Spitzer.
The lawsuit, filed in New York State Supreme Court, said Glaxo suppressed four studies that failed to demonstrate the drug was effective in treating children and adolescents and suggested an increase of suicidal thinking and acts.
It also said an internal 1999 Glaxo document showed that the company intended to “manage the dissemination of data in order to minimize any potential negative commercial impact.”

rookmb

Antidepressants don't make you fat. Over eating does.

^^^^^^

All people are different. I have been on anti-depressants for several years. They were not the reason I gained weight. My weight gain was due to the fact that I was eating WAY too much and not exercising.

skmolove

i think it all depends on the medication. wellbutrin actually has been know to help with weight loss because it allows you to controll IMPULSIVE behaviors. hummm impulsive eating anyone?? yuuup that WAS me! meds taken with counseling is helpful to change behavior...just sayin'

mfpcopine

Antidepressants don't make you fat. Over eating does.

That's not true. Some antidepressants affect the metabolism and the individual simply processes food differently. It's a reported side effect, and I've read articles in which people talked about this SE. One woman said a certain drug (don't recall which one) had saved her life, but she'd gained 70 pounds.

saragato

OP from what it sounds like you only had what's called situational depression. In that case you're only on anti-depressants for a certain amount of time and it's preferred you supplement it with therapy or just flat out try therapy before drugs. Whoever diagnosed you with depression should have suggested that first or at least alongside it depending on your insurance and your budget.

Most if not all psych meds have a side effect of weight gain. They also have side effects of depression (irony) and other things. If what you get prescribed gives you a side effect you cannot live with, you ask to either be changed to something else or you ask if the doctor believes you're well enough to stop taking them. Pretty much goes for any and all medication.

But really you can't place all the blame on the medication. Sure it helped, but you didn't exactly stop it or question it, did you?

fragilegift

I tend to place some blame for the weight gain on Anti depressants as well. The most notable was Zoloft/sertraline. (I've had lexapro/escitalopram and aropax/paroxetine in there as well, plus a couple of others so long ago I don't recall their names.) That totally buggered up my tummy. I felt nauseous eating more than two bites of anything. So Dr put me on a stomach settling drug. Then I couldn't sleep. So he added ANOTHER anti to help with that. After that I could sleep 16 hours a day, wake up, be foggy and go back to sleep again.

Eventually I took myself off all of those. Slowly, but without his approval. I was of the belief he would just prescribe ANOTHER drug.

I wasn't 'better' off them, so I went back to the Dr, and was put on Fluoxetine (prozac). That worked fine, but I would have put a lot of the weight on with the other cocktail. I still didn't have any motivation though. I remember waking up one day and realising that it was 'quiet in there' (my head). The negative voices had finally shut up.

Early 2009 I started doing tae-bo of a morning. That raised the endorphins enough that a week had gone by before I realised I hadn't had a pill. I stayed doing that for a while, and eventually stopped taking them. Coming off those didn't mess with my head half as much as the Zoloft.

I've been drug free ever since.

mfpcopine

When I was 19, I was looking good at 135lbs, flat tummy and all. Suddenly I was hit with a curveball- a bad, heartbreaking break up that consisted of moving out. Since I had always suffered from anxiety, and medication was in contemplation in the past anyway, I went on anti-depressants. MISTAKE! I immediately gained 20lbs. I'm talking within a month or 2! I faught the weight gain as much as I could, but nothing ever happened. I will say that I certainly wasn't as motivated as I am now. I finally went off of them last June and dropped about 5lbs in a few months without doing anything. I always told myself that I NEED to lose this weight. I'm sick of it. But I never had the motivation. Not even for my wedding! So now here I am, motivated and 14lbs down! Never again will I go on anti-depressants.

I understand. Many years ago, after trying various things, I was prescribed an antidepressant that caused weight gain. The unfortunate thing is that it actually worked -- I felt better -- and if you are ever in any doubt as to whether as mental hygiene drug is working, it's very simple. You don't feel depressed. You don't feel euphoric (they're not "happy drugs"). It's like taking an aspirin when you have a bad headache. Your headache goes away. You feel lighter and more energetic.

But in a very short time my weight rocketed (for me). I tried to work out, but I was exhausted every time I got on the treadmill. I was eating the same food, but started piling on the pounds. I complained to the doctor after two months. He wanted me to continue, but I cited reports from other doctors on the web who said that the depression caused by weight gain from these drugs could not be ignored; it was not trivial; patients, especially women, are not living in a cultural vacuum and women are judged harshly for being overweight or obese. Even older people were depressed by the weight gain. The doctors said that if the patient could not tolerate the SE the doctor should stop it.

So I went off it. If I'd been suicidally depressed, I would have tried to stay on it, but in my then-existing state it simply wasn't worth it. I would have been substituting one problem for another.

To be absolutely clear: I AM NOT ANTI PSYCHOTROPIC DRUGS. They save lives.

puddleglum999

Anti-depressants indirectly caused my weight gain by completely killing my motivation to do anything. I could hardly force myself to get off the couch so I just ordered booze and pizza and wasted a year of my life. I've been on six different anti-depressants which have caused derealization, self-harm, weight gain, the lack of any feelings, near-constant thoughts of suicide, violent panic attacks, etc.. etc.... It makes me sick when I think of all those years the drugs took from me and I'll never get back, and it makes me feel even worse when I think of how my family doctor, who had known me my entire life, had no problems putting a 12 year old with occasional sad spells on this mind-altering drug, and continuing to convince me that I needed drugs, that there was something wrong with me, that I wasn't going to be okay without them. She never once suggested exercise or a healthy diet. 10 years after I started taking pills I quit, against her wishes. The withdrawals were a nightmare, but 1 year later I feel like a new person ... no anxiety, no depression, I have feelings and dreams and a life again. Clearly I went off a tangent but the more I learn about the pharmaceutical industry the more disgusted and sad I feel, good luck to everyone with their journey, with or without medication xx

mfpcopine

I am wondering if anti depressants are preventing me from weight loss? I'm on fluexotine and although I've not heard or anyone gaining weight because if it I believe it may be one of the factors as well as PCOS. I eat a diet rich in vegetables and fruit - not fair!

Interesting. When Prozac (Fluoxotine) was first introduced, magazines were full of articles on how a common side effect was weight loss.

jg627

My advice, you don't have to take it or agree with it, try to change your life without taking these drugs unless you absolutely have to. This is one of those cure is worse than the disease situations.

I agree. I think taking it for a short time is ok, but try and get off it as soon as possible. Side affects are horrible. Good luck!

If you have ever been TRULY depressed, you wouldn't say things like "go off your meds" so lightly. For some people, not being on their meds is a death sentence! This really is an area where if you are not qualified and don't have their personal medical records in your hands, you probably should not being saying such things because "someone" out there may take your advice and end up dead. I wouldn't want that on my shoulders!

After my sister was murdered, it took a month to find the body. Afterwards I locked myself in the basement for a long time and used empty pop bottles to pee in, so believe me, I know what it's like to be truly depressed and I do not take it lightly.

I'm sorry about your sister.
I agree that antidepressants should be avoided. I can't believe doctors hand them out like candy and people take them like they are the missing piece of the puzzle. Depression and sadness are a NORMAL part of life. These drugs exist to make people money, not to make people feel better. I resent that they are being taken in such high numbers that they are found in our drinking water and are doing untold damage to marine life.

There is a difference between real depression and the depression you are obviously talking about. Depression as in feeling like you want to die every second of the day. With an imbalance in the brain. It is an illness like no other. Should they should giving chemo to cancer patients? No. So why should they stop giving antidepressants to people who legit NEED them. At one point in my life I was on them and although after I started exercising I became so much happier I was able to come off them, It is not that easy for some people.

Now, to be clear, I never actually said "go off your meds". Somebody else did and credited me as the author of the quote.

floridagirl7264

Antidepressants don't make you fat. Over eating does.

This is so true. I'm on 5 different meds. One of the meds that I tried caused intense sugar cravings and I ended up gaining 60 lbs. before I was finally taken off of it. Now I'm on a different one and I have no cravings. So it was the overeating that caused the weight gain, but it was the med that caused the cravings. I just wanted to add that I'm bipolar with major depressive disorder. The meds literally saved my life. Without them, I wouldn't be sitting here typing this.

mfpcopine

Is it usual to take antidepressants for a break-up? Am just curious .... I know breakups can cause real pain, but antidepressants seem a significant step ... to me??

Sean

As mentioned, I had always had anxiety and bouts of depression. This break-up was the last straw in what I could handle. I don't think I need to go too far into detail about my life, but like eveyone else's, it isn't easy.
Now I'm in a much better mental state. I no longer take them.



MIND OVER MATTER!

Oh, please. There's a reason patients are prescribed drug therapy by responsible physicians. "Positive Thinking" is not enough. There's a problem with their brain chemistry, in addition to whatever external events have an influence.


NOTE: I didn't realize it was the OP who said "Mind over Matter." That puts the quote in a different light.

saragato

Antidepressants don't make you fat. Over eating does.

This is so true. I'm on 5 different meds. One of the meds that I tried caused intense sugar cravings and I ended up gaining 60 lbs. before I was finally taken off of it. Now I'm on a different one and I have no cravings. So it was the overeating that caused the weight gain, but it was the med that caused the cravings.

The difference there being the medication is the easier variable to change. It's very important to research any and all medication you're on to know what to look for and when/if to know that it's the medicine causing the behavior change and not you entirely.

puddleglum999

Yes, there is a reason Drs prescribe drugs, it's green and has a dead president on it. There is NO SCIENTIFIC EVIDENCE of any such thing as a "chemical imbalance" causing depression. Do some research, you'll be surprised what you find

saragato

Is it usual to take antidepressants for a break-up? Am just curious .... I know breakups can cause real pain, but antidepressants seem a significant step ... to me??

Sean

As mentioned, I had always had anxiety and bouts of depression. This break-up was the last straw in what I could handle. I don't think I need to go too far into detail about my life, but like eveyone else's, it isn't easy.
Now I'm in a much better mental state. I no longer take them.


MIND OVER MATTER!

Oh, please. There's a reason patients are prescribed drug therapy by responsible physicians. "Positive Thinking" is not enough. There's a problem with their brain chemistry, in addition to whatever external events have an influence.

Apparently the physician wasn't responsible because she didn't have a type of depression that even NEEDED medication. If it was clinical or something traumatizing then yes medication is the best route to go, but for someone who's just having a minor rough patch, aka situational depression, you're usually given a therapist, maybe something to take the edge off if you need it, and you learn to get over it. In that case it is a matter of "Mind over matter" because it wasn't something critical anyway.

saragato

Yes, there is a reason Drs prescribe drugs, it's green and has a dead president on it. There is NO SCIENTIFIC EVIDENCE of any such thing as a "chemical imbalance" causing depression. Do some research, you'll be surprised what you find

I'm sure if you met me clean from my medication (I'm bipolar, by the way, also known as a manic depressive) you'd change your tune, buster.

You wanna have a soapbox for your stuff about anti-medication and conspiracy theories, make your own thread or use your blog. Otherwise you're basically trolling.

floridagirl7264

Antidepressants don't make you fat. Over eating does.

This is so true. I'm on 5 different meds. One of the meds that I tried caused intense sugar cravings and I ended up gaining 60 lbs. before I was finally taken off of it. Now I'm on a different one and I have no cravings. So it was the overeating that caused the weight gain, but it was the med that caused the cravings.

The difference there being the medication is the easier variable to change. It's very important to research any and all medication you're on to know what to look for and when/if to know that it's the medicine causing the behavior change and not you entirely.

Research was done and sugar cravings were not a side effect (I guess for the majority of people). If I can get off of any of these meds, I would. Unfortunately, I can't.

Brook70

Bump

mfpcopine

I'm not saying that someone with depression doesn't need help, I am saying they don't need these pills.

You are misinformed. Some people require drug therapy because part of their problem is physiological. They can't exercise themselves out of Clinical Depression. All medications have risks. Good, responsible doctors monitor their patients and SEs such as suicidal ideation are well known.