Calories in calories out what science says

and just for fun here is the complete abstract from 2004 - without parts omitted for lol's

Nutr Metab (Lond). 2004 Dec 8;1(1):15.

Affiliation
Abstract
BACKGROUND: It is commonly held that "a calorie is a calorie", i.e. that diets of equal caloric content will result in identical weight change independent of macronutrient composition, and appeal is frequently made to the laws of thermodynamics. We have previously shown that thermodynamics does not support such a view and that diets of different macronutrient content may be expected to induce different changes in body mass. Low carbohydrate diets in particular have claimed a "metabolic advantage" meaning more weight loss than in isocaloric diets of higher carbohydrate content. In this review, for pedagogic clarity, we reframe the theoretical discussion to directly link thermodynamic inefficiency to weight change. The problem in outline: Is metabolic advantage theoretically possible? If so, what biochemical mechanisms might plausibly explain it? Finally, what experimental evidence exists to determine whether it does or does not occur?

RESULTS: Reduced thermodynamic efficiency will result in increased weight loss. The laws of thermodynamics are silent on the existence of variable thermodynamic efficiency in metabolic processes. Therefore such variability is permitted and can be related to differences in weight lost. The existence of variable efficiency and metabolic advantage is therefore an empiric question rather than a theoretical one, confirmed by many experimental isocaloric studies, pending a properly performed meta-analysis. Mechanisms are as yet unknown, but plausible mechanisms at the metabolic level are proposed.

CONCLUSIONS: Variable thermodynamic efficiency due to dietary manipulation is permitted by physical laws, is supported by much experimental data, and may be reasonably explained by plausible mechanisms.

:yawn:

Theory in science does not mean what you think it means.

CONCLUSIONS: Variable thermodynamic efficiency due to dietary manipulation is permitted by physical laws, is supported by much experimental data, and may be reasonably explained by plausible mechanisms.

Yup. That is why each person's calories out is different. But for each person, it is still calories in, calories out.

For some reason the very simplicity of this phenomenon confounds so many people.

Yes each persons calories out is different. Making each person need a different calories in. So you could enter your basic specs into one of these websites to find your tdee and bmr, eat the way it says and still not lose....BECAUSE of variables. Its not 100%

Sure it is, because the only other variable is the output (exercise and activity) and you control that. If you enter that you workout 6 days a week on a TDEE and then only workout 3days, you can expect that your output will not match the input that you entered and you will not expend what you told TDEE you would. In other words - calories in, calories out.

This is fun. Let's keep going. :bigsmile:

CONCLUSIONS: Variable thermodynamic efficiency due to dietary manipulation is permitted by physical laws, is supported by much experimental data, and may be reasonably explained by plausible mechanisms.

Yup. That is why each person's calories out is different. But for each person, it is still calories in, calories out.

For some reason the very simplicity of this phenomenon confounds so many people.

Yes each persons calories out is different. Making each person need a different calories in. So you could enter your basic specs into one of these websites to find your tdee and bmr, eat the way it says and still not lose....BECAUSE of variables. Its not 100%

Sure it is, because the only other variable is the output (exercise and activity) and you control that. If you enter that you workout 6 days a week on a TDEE and then only workout 3days, you can expect that your output will not match the input that you entered and you will not expend what you told TDEE you would. In other words - calories in, calories out.

This is fun. Let's keep going. :bigsmile:

Yes and different peoples bodies expel it differently. Some people burn more than others. So there is no real exact way to know anything. Its all a general estimate. My body might break down 1500 calories differently then someone elses body. People on these forums act like metabolisms don't exist.

I have been on calorie counter and myfitness pal enough to know, you people are basically full of ****. You do nothing but spout out misinformation, you reiterate from websites. Doctors and nutritionists are full of crap didn't you know? Its the people on myfitnesspal who know best......

I must have scrolled past all your supporting documentation.

Most doctors and nutritionists I know rely on CICO.

What's the question again?

For anyone interested, full text of the abstract that the OP posted, without actually citing the source....tsk tsk..


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC543577/


Still no idea what the question is though