Leaky gut

Best wishes OP

@queenliz99 @HippySkoppy @PeachyCarol I am glad your lives are better because of the Rx meds.

I too was willing to risk the diseases that can come with the 100% chance of developing a deficient immune system. I researched cancer treatments used in Europe and Japan and actively implemented two different protocols to see if they had any short term side effects should I develop cancer from starting the Enbrel injections.

In my case there was nagging sense there was a way to get the pain relief that Enbrel could offer by just changing my way of eating. It worked within 30 days and I was able to tell the doctors NO to Enbrel. It also cured my 40 years of IBS and enabled body to start to regain its health at the age of 63.

My point for those averse to increasing their risks of failing health long term due to taking this class of drugs that they may want to research a new way of eating that might offer them the same pain relief without the known side effects. I do not advise others to do what I have done. I do suggest to others if interested in diet options to do the research and then weigh the Pros and Cons before acting any any direction.

Will cutting out all grains and most all sugars work for another to manage autoimmune disease pain?

There is no $$$ cost or health risks to find out yes or no.

I do not blindly follow any medical, religious or financial advice from others. With the knowledge at the fingertips of any one reading this post each of us can successful research any subject that we desire. That was not even possible for healthcare professionals just 30 years ago.

Being in the 1% category for cancer and the 100% category for a wrecked immune system are not odds I wanted to take when I learn there was zero to be gained in my case by using Enbrel. Even my way of eating to manage my pain lowers my risk from both cancer and heart disease.

Best of success with any treatment/diet plan one selects. We are all different and there is more than one road to improving health.

emtjmac wrote: »

I don't have celiac disease or a "leaky gut" but I do have an autoimmune disease called eosinophillic esophagitis. My personal experience has been that removing gluten from my diet was a very good choice. My bloating has gone way, way down and I feel much better overall. Without the bloat I was suffering from I can breathe easier and work harder at the gym and during my runs. I'm not an expert and neither are the people who will tell you that you don't need to avoid gluten unless you've been diagnosed with crone's disease. Talk to your doctor about your symptoms and try it if you think it might work for you. It's actually extremely easy, most foods are gluten free. I don't miss bread very much and I've found a quinoa based pasta that I really like so I'm good with the small sacrifices I've had to make. Good luck!

Had to chime in. My 12yo was diagnosed with eosinophilic esophagitis a year ago. Horrible chronic vomiting, pain, diarrhea for a LONG time. So far he's had 7 upper endoscopies and a few more to go and has been on a strict, controlled diet to determine which foods are causing this. It's caused by food allergies (in kids - not sure about adults). I was so sure he had celiac because we have a strong family history but I was wrong. So thankful he's been super healthy since changing his diet. Pretty sure it's allergies to peanuts and dairy.

If you have an autoimmune disease your immune system is already messed up. It is attacking your body. The only relief I have had is suppressing it with a biologic (Remicade) and imuran. I rather not be running to the bathroom 20x a day, lots of blood loss, severe pain, etc and not be able to leave the house. Yes I have trigger foods but in a flair all food is triggering even water. Cutting out gluten and sugar is not a cure as there are no cures for any autoimmune disease.

Biologics are usually last resort drugs. I was very very sick when I was diagnosed as I ignored symptoms for years. (I have IBS too and just thought my symptoms were due to that or lactose intolerance). I was hospitalized for 34 days straight from my colonoscopy and my Dr put me on Remicade right away. I didn't feel anything on it until my 6th dose. Tmi it makes me have formed bowel movements about 75% of the time. I hadn't had this in years. I went from 20x a day to 3-4 x a day.

Vitamin d definitely helps. Lots of studies recommending it for Crohn's

mine gets leaky, when I get into the drink.

neohdiver wrote: »

3dogsrunning wrote: »

Do you have any pubmed articles to link?

Here's a sampling - since you didn't specify a particular area of interest:

Vancomycin - two case reports: http://www.ncbi.nlm.nih.gov/pubmed/19840535; http://www.ncbi.nlm.nih.gov/pubmed/6853034

IBD and permeability/leaky gut: http://www.ncbi.nlm.nih.gov/pubmed/26582965, http://www.ncbi.nlm.nih.gov/pubmed/26512799

Connection between liver disorder & permeability/leaky gut: http://www.ncbi.nlm.nih.gov/pubmed/26556989

Metabolism and gut permeability: http://www.ncbi.nlm.nih.gov/pubmed/26506213

Intestinal permeability and Parkinson's: http://www.ncbi.nlm.nih.gov/pubmed/26457021

IBS and gut permeability: http://www.ncbi.nlm.nih.gov/pubmed/25734736

As you can see from the sampling, it is a fairly hot topic these days.

Always read your sources.

First two articles focus on renal failure and insufficiency for proper clearance of the drug.

The IBD reference suggests a mechanism for increases "ovalbumin transport, probably by augmented transcytosis" and not an increase in general permeability...

MarziPanda95 wrote: »

'Leaky gut' is a complete myth. If your gut leaked you'd be in the hospital with blood poisoning! Sounds like you have a food intolerance. I agree with those that suggested trying an elimination diet to test what triggers it. Might be IBS.

Leaky gut is a bad name for chronic intestinal inflammation that causes a variety of real medical problems. I started in the same place you are. But getting my son scoped because he'd been vomiting for a year and SEEING the inflammation and, in a relative, the villi that were GONE because of autoimmune response (she has celiac and 'leaky gut') made me a believer.

It is called leaky gut because when it's really bad the cells are so swollen, the barriers can break down - no poop doesn't leak out, but the barrier is more permeable than it should be.

Different people also react differently to the same problem. My husband and sons are unable to digest tyramine (husband and one son) and sensitive to gluten (all), milk dairy, and eggs (one son). For my husband, it led to diverticulitis (he had to have a foot of his intestine removed), chronic bloating, and diarrhea. For another son, it led to gas. To the third, incredibly brain 'fog' caused by the tyramine buildup resulting in functionally low dopamine and serotonin levels and severe chronic pain and sensitivity to light and sound. He almost failed out of school until he changed his diet.

Measurably, after diagnosis with sensitivities and removing them from his diet my husband lost 12" (yes really) on his belly. My son with chronic migraines is finally getting better. He can now think again.

Like lots of real medical problems, people get on a bandwagon, there are quacks out there, and lots of people say they have a problem that really don't. That doesn't mean the original issue isn't real and doesn't need treatment.

If they saw chronic inflammation on the scope wouldn't that be IBD?