Effects of Sucralose on Glucose Transport and Other Parameters Inovlved in Bdoy Weight Regulation

Caffeine is an agonist of adenosine receptors, adenosine being a common cell signalling transmitter. What that means is that caffeine binds to and blocks the signalling of receptors that normally bind adenosine so it deadens the signal from adenosine. Adenosine receptors in your brain are associated with neurotransmissions related to sleep (https://www.ncbi.nlm.nih.gov/pubmed/21401496) but adensoine receptors are all over your body carrying out many different functions all of which caffeine is going to affect. Another affect caffeine has for example is vasoconstriction, causing your blood vessels to tighten, which can cause headaches....but there are probably hundreds of effects all over your body. The active ingredient in chocolate, theobromine ,does the same thing as does Xanthine which is found in tea amongst other things. In fact you can sort of tell that they might block this receptor just by looking at the molecules in comparison to adenosine



If caffeine was a new product in the current enviornment I bet there would be a huge backlash to it from the anti-chemical crowd given that it literally blocks neurotransmitters in your brain. But its been grandfathered in so its largely ignored.