Your questions, hypotheses, and curiosities?

girlviernes
girlviernes Posts: 2,402 Member
edited November 17 in Health and Weight Loss
I think most of us here agree on some basics, such as that you need a calorie deficit to lose weight. But what are the aspects of weight loss and health that you personally have questions about, wonder about, or have your own hypotheses about?
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Replies

  • girlviernes
    girlviernes Posts: 2,402 Member
    I usually eat moderate amount of carbs (~100 net), often have a high level of activity, and I have symptoms that seem similar to "keto flu." So a hypothesis that I have is that I am getting repeatedly depleted (especially when active) but not actually switching into ketosis because my carbs are not that low, and I have days that I am closer to 150-200g on a regular basis.
  • girlviernes
    girlviernes Posts: 2,402 Member
    I've found some very interesting studies on rats weighing less when eating the same number of kcals but within a constricted time frame rather than at any time, so I am very curious about what accounts for the difference. My understanding is that the circadian rhythms are also more defined, so I wonder if sleep and hormonal balance is improved and/or if activity level increases.
  • janejellyroll
    janejellyroll Posts: 25,763 Member
    Some of mine:

    I have read over the years that eating a high fiber diet can slightly reduce the number of calories that your body absorbs because everything is moving through your intestine faster. I have no idea if this is true or if it has ever been tested.

    Why do people have such dramatically different experiences with which types of foods cause satiety?



  • PeachyCarol
    PeachyCarol Posts: 8,029 Member
    I, like you, moderate my carbs, and don't know that I've ever been in ketosis. Even when I low carbed. I don't know what it feels like vs. normal feeling or what keto flu feels like vs. a normal bad day I might have due to my arthritis.

    So now you have me wondering about it, because my carb intake fluctuates since I'm a vegetarian, and I tend to have higher carb days on days when I'm eating beans for my main meal.
  • girlviernes
    girlviernes Posts: 2,402 Member
    We see pretty terrible weight loss maintenance outcomes in formal research studies, I wonder how this compares to people just making changes on their own or informally.
  • DeguelloTex
    DeguelloTex Posts: 6,652 Member
    I wonder if, or how much, I'm affected by adaptive thermogenesis.
  • janejellyroll
    janejellyroll Posts: 25,763 Member
    We see pretty terrible weight loss maintenance outcomes in formal research studies, I wonder how this compares to people just making changes on their own or informally.

    Question: are most of these studies done on people with significant weight to lose? Or do they do studies on people who are losing 20-30 pounds to see how they maintain it?
  • girlviernes
    girlviernes Posts: 2,402 Member
    Some of mine:

    I have read over the years that eating a high fiber diet can slightly reduce the number of calories that your body absorbs because everything is moving through your intestine faster. I have no idea if this is true or if it has ever been tested.

    Why do people have such dramatically different experiences with which types of foods cause satiety?

    Interesting, I had never heard that about a high fiber diet. Some thing I have heard (perhaps from Michael Pollan) is that high fiber may facilitate healthy gut bacteria which may impact us in various ways.

    I like your question about satiety... hmmm... I also wonder with this to what extent placebo comes into play.
  • girlviernes
    girlviernes Posts: 2,402 Member
    We see pretty terrible weight loss maintenance outcomes in formal research studies, I wonder how this compares to people just making changes on their own or informally.

    Question: are most of these studies done on people with significant weight to lose? Or do they do studies on people who are losing 20-30 pounds to see how they maintain it?

    Typically they will be people in the obese range, I think an average BMI of 35 would be fairly typical. Researchers will want to maximize effects by starting with people with more to lose. However, a typical weight loss outcome in these studies would be 5-10% of starting weight (with a few people losing significantly more than that)

  • janejellyroll
    janejellyroll Posts: 25,763 Member
    Some of mine:

    I have read over the years that eating a high fiber diet can slightly reduce the number of calories that your body absorbs because everything is moving through your intestine faster. I have no idea if this is true or if it has ever been tested.

    Why do people have such dramatically different experiences with which types of foods cause satiety?

    Interesting, I had never heard that about a high fiber diet. Some thing I have heard (perhaps from Michael Pollan) is that high fiber may facilitate healthy gut bacteria which may impact us in various ways.

    I like your question about satiety... hmmm... I also wonder with this to what extent placebo comes into play.

    That's a really good thought about the placebo effect! I find that I have to focus on my protein intake to get enough and when I sit down to high protein meals I'm very aware of it. I have to question anything I notice about my satiety from that point forward. If I'm correct, even being aware of the placebo effect doesn't make one immune to it.

  • girlviernes
    girlviernes Posts: 2,402 Member
    I, like you, moderate my carbs, and don't know that I've ever been in ketosis. Even when I low carbed. I don't know what it feels like vs. normal feeling or what keto flu feels like vs. a normal bad day I might have due to my arthritis.

    So now you have me wondering about it, because my carb intake fluctuates since I'm a vegetarian, and I tend to have higher carb days on days when I'm eating beans for my main meal.

    This is one of the reasons I toy with the idea of keto - just having the knowledge of what it feels like.
  • freeoscar
    freeoscar Posts: 82 Member
    Not a question or hypothesis, but it amazes me how little we actually know about nutrition and weight loss. Take virtually any topic and I can go out and get studies which offer contradictory results.
  • DeguelloTex
    DeguelloTex Posts: 6,652 Member
    We see pretty terrible weight loss maintenance outcomes in formal research studies, I wonder how this compares to people just making changes on their own or informally.

    Question: are most of these studies done on people with significant weight to lose? Or do they do studies on people who are losing 20-30 pounds to see how they maintain it?

    Typically they will be people in the obese range, I think an average BMI of 35 would be fairly typical. Researchers will want to maximize effects by starting with people with more to lose. However, a typical weight loss outcome in these studies would be 5-10% of starting weight (with a few people losing significantly more than that)
    I was 35.89. I'm going to be a special snowflake who maintains his loss.

  • girlviernes
    girlviernes Posts: 2,402 Member
    We see pretty terrible weight loss maintenance outcomes in formal research studies, I wonder how this compares to people just making changes on their own or informally.

    Question: are most of these studies done on people with significant weight to lose? Or do they do studies on people who are losing 20-30 pounds to see how they maintain it?

    Typically they will be people in the obese range, I think an average BMI of 35 would be fairly typical. Researchers will want to maximize effects by starting with people with more to lose. However, a typical weight loss outcome in these studies would be 5-10% of starting weight (with a few people losing significantly more than that)
    I was 35.89. I'm going to be a special snowflake who maintains his loss.

    We are all going to be special snowflakes, dammit!
  • girlviernes
    girlviernes Posts: 2,402 Member
    freeoscar wrote: »
    Not a question or hypothesis, but it amazes me how little we actually know about nutrition and weight loss. Take virtually any topic and I can go out and get studies which offer contradictory results.

    This is very true, although, also part of the nature of scientific progression.

  • PeachyCarol
    PeachyCarol Posts: 8,029 Member
    We see pretty terrible weight loss maintenance outcomes in formal research studies, I wonder how this compares to people just making changes on their own or informally.

    Question: are most of these studies done on people with significant weight to lose? Or do they do studies on people who are losing 20-30 pounds to see how they maintain it?

    Typically they will be people in the obese range, I think an average BMI of 35 would be fairly typical. Researchers will want to maximize effects by starting with people with more to lose. However, a typical weight loss outcome in these studies would be 5-10% of starting weight (with a few people losing significantly more than that)
    I was 35.89. I'm going to be a special snowflake who maintains his loss.

    We are all going to be special snowflakes, dammit!

    QFT!

  • zyxst
    zyxst Posts: 9,149 Member
    How come there are times when I overeat way over my calorie goal and lose weight? Of course, the reverse on that - gaining weight while eating at a deficit?

    Can we get better definitions for find activity levels? WTF is considered "moderate" exercise?

    Once you have it, does acanthosis nigricans ever go away?
  • girlviernes
    girlviernes Posts: 2,402 Member
    zyxst wrote: »
    How come there are times when I overeat way over my calorie goal and lose weight? Of course, the reverse on that - gaining weight while eating at a deficit?

    Can we get better definitions for find activity levels? WTF is considered "moderate" exercise?

    Once you have it, does acanthosis nigricans ever go away?

    I have heard that acanthosis nigricans can go away but I'm not sure how common that is. I hope so!




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  • futuremanda
    futuremanda Posts: 816 Member
    I wonder about the physical changes that happen when we strength train in a deficit. I know I'm not building muscle mass -- especially as I am not lifting heavy, I am doing bodyweight exercises. I do feel changes in my body (especially in leaner areas, where there's less fat over the muscle) though. These changes persist even if I stop working out for a few days (as in, now, because I'm sick). Does neural adaptation change anything in a way that I could feel? Is it all in my head -- maybe an effect of being able to better activate / more likely to properly activate muscles when I do things, or just because I want to? Wouldn't affect my actions any, but I am curious.
  • AuburnL
    AuburnL Posts: 13 Member
    edited April 2015
    BFDeal wrote: »
    You hear all the time "even if the scale isn't moving maybe you're lost inches." OK, so assuming the person in question is in a deficit (and therefore of course can't build muscle) someone explain this logically. How does one get physically smaller but not lose weight? Second, can the opposite occur? As in, can one GAIN inches (again, in a deficit) but have the scale drop? Go.

    It's definitely possible because I'm eating at a deficit and have lost inches (and pounds) everywhere except my calves. I've gained close to half an inch in both of my calves (more in my left one for some reason, a bit less on my right). I am training for a long hike and am doing lots and lots of hill walking and stair climbing. All my skinny jeans now gap at the waist but are tighter in my calves! Good thing it's not tall boot season I guess because I had trouble finding ones that fit before. Now I'm really screwed. :lol:

    (my stats in my profile are not updated. I'm tracking elsewhere which I suppose we probably aren't supposed to link to)
  • maidentl
    maidentl Posts: 3,203 Member
    Something I pondered on my walk today. In a recent thread, some people mentioned that walking burns practically nothing and isn't even worth logging. SO, I was thinking, MFP gives me 1200 at sedentary. I get 200-300 more if I get my booty up to 10K steps. But if walking, especially "just walking around your house" burns nothing, is my Fitbit giving me too many calories? I know, only time will tell . . . :astonished:
  • DeguelloTex
    DeguelloTex Posts: 6,652 Member
    BFDeal wrote: »
    You hear all the time "even if the scale isn't moving maybe you're lost inches." OK, so assuming the person in question is in a deficit (and therefore of course can't build muscle) someone explain this logically. How does one get physically smaller but not lose weight? Second, can the opposite occur? As in, can one GAIN inches (again, in a deficit) but have the scale drop? Go.
    I think this is mostly used in the context of water weight or the like masking a loss when the scale is the only measure being considered.

  • azulvioleta6
    azulvioleta6 Posts: 4,195 Member
    zyxst wrote: »
    How come there are times when I overeat way over my calorie goal and lose weight? Of course, the reverse on that - gaining weight while eating at a deficit?

    Can we get better definitions for find activity levels? WTF is considered "moderate" exercise?

    Once you have it, does acanthosis nigricans ever go away?

    I have heard that acanthosis nigricans can go away but I'm not sure how common that is. I hope so!

    It can. Mine has pretty much disappeared.
  • azulvioleta6
    azulvioleta6 Posts: 4,195 Member
    maidentl wrote: »
    Something I pondered on my walk today. In a recent thread, some people mentioned that walking burns practically nothing and isn't even worth logging. SO, I was thinking, MFP gives me 1200 at sedentary. I get 200-300 more if I get my booty up to 10K steps. But if walking, especially "just walking around your house" burns nothing, is my Fitbit giving me too many calories? I know, only time will tell . . . :astonished:

    My observation, just for my own body, is that moderate walking alone does very little for weight loss. However, I seem lose and maintain better when I am adding extra walking on TOP of my regular hour/per day of more intense working out. So if I swim, do dance fitness, run, or lift AND walk 12,000+ steps/day, I do better than just doing the more intense workout and not getting much walking throughout the day.

    I also notice that several bursts of activity throughout the day seem more effective than just one long workout.

    Giving yourself extra calories for a normal amount of walking (10,000 steps) doesn't make a lot of sense.
  • azulvioleta6
    azulvioleta6 Posts: 4,195 Member
    We see pretty terrible weight loss maintenance outcomes in formal research studies, I wonder how this compares to people just making changes on their own or informally.

    I think that practitioners would tell you the same thing.

    I definitely get treated like a special snowflake, particularly by my specialists. I still have more weight to lose, but I've made a big dent and have maintained for several years. Apparently this is incredibly rare for people who have my issues. My endocrinologist just about does a dance every time he sees me. He is clearly tickled to see that I haven't re-gained the weight. :)
  • azulvioleta6
    azulvioleta6 Posts: 4,195 Member
    Some of mine:

    I have read over the years that eating a high fiber diet can slightly reduce the number of calories that your body absorbs because everything is moving through your intestine faster. I have no idea if this is true or if it has ever been tested.

    Why do people have such dramatically different experiences with which types of foods cause satiety?

    Interesting, I had never heard that about a high fiber diet. Some thing I have heard (perhaps from Michael Pollan) is that high fiber may facilitate healthy gut bacteria which may impact us in various ways.

    I like your question about satiety... hmmm... I also wonder with this to what extent placebo comes into play.

    Not a question or a hypothesis, but I would like to know a lot more about the microbiome. I'm very curious to see how an increased understanding will inform actual treatments over the next 10-20 years.
  • DeguelloTex
    DeguelloTex Posts: 6,652 Member
    Giving yourself extra calories for a normal amount of walking (10,000 steps) doesn't make a lot of sense.
    For the longest time, my goal was 10,000 steps. I'm not sure that's "normal" but, regardless, it's been worth about .75 pounds a week for me over the last year. More when I was heavier, less now, but not insignificant.

  • azulvioleta6
    azulvioleta6 Posts: 4,195 Member
    Giving yourself extra calories for a normal amount of walking (10,000 steps) doesn't make a lot of sense.
    For the longest time, my goal was 10,000 steps. I'm not sure that's "normal" but, regardless, it's been worth about .75 pounds a week for me over the last year. More when I was heavier, less now, but not insignificant.

    Interesting. Are you doing more intense workouts in addition to the walking?

    This brings up another question that I have wondered about. Do different individuals have different set-points for activity?

    I am very active again now, but really I am just back to what was normal for me before I had health problems which forced me to be sedentary. The amount of exercise that seems to be sufficient for most people to maintain weight loss is not NEARLY enough for me. Some of this is due to metabolic illness in my case, but there seems to be more to it than that.
  • Jruzer
    Jruzer Posts: 3,501 Member
    I wonder about:
    1. How much natural variability is there in RMR between people? I've seen a few studies but would like to have a better understanding. Everyone acts as if the Katch-McArdle/Harris-Benedict/Mifflin-StJeor are actual physical models rather than quasi-empirical fits. I think that I have a more active metabomolism than the average.

    2. How much can digestive efficiency vary within an individual and between individuals? What are the important variables determining this?
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