Interesting Studies: Probably low carb related in one way or another

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  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    edited September 2018
    Twitter thread
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    Evaluation of a ketogenic diet for improvement of neurological recovery in individuals with acute spinal cord injury: a pilot, randomized safety and feasibility trial

    Our pilot findings primarily demonstrated that KD is safe and feasible to be administered in acute SCI. Furthermore, upper extremity motor scores were higher (p < 0.05) in the KD vs. SD group and an anti-inflammatory lysophospholipid, lysoPC 16:0, was present at higher levels, and an inflammatory blood protein, fibrinogen, was present at lower levels in the KD serum samples vs. SD serum samples.

    Conclusion

    Taken together, these preliminary results suggest that a KD may have anti-inflammatory effects that may promote neuroprotection, resulting in improved neurological recovery in SCI. Future studies with larger sample size are warranted for demonstrating efficacy of KD for improving neurological recovery.

    Source
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    Effect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients

    The results of this study evidenced that the rapid and sustained weight and FM loss induced by VLCK-diet are associated with good food control and improvements in the psychological well-being parameters in obese subjects that could be reinforced by the effect of ketosis. This effect could contribute to long-term success of this therapy and further reinforce the suitability of a VLCK-diet as a viable and valuable treatment option for obesity.

    Source
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    Development of the Highly Processed Food Withdrawal Scale

    Food addiction posits that highly processed foods may be capable of triggering addictive-like symptoms in some individuals, including withdrawal.
    Paralleling the course of drug withdrawal, symptoms assessed by the ProWS were reported as most intense between days 2–5 during an attempt to cut down.

    Source
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    I haven't watched these yet but they're generating some buzz:
    And if you're interested in those Baker & Bitter's Human Performance Outliers Podcast might interest you.
  • nvmomketo
    nvmomketo Posts: 12,019 Member
    E
    AlabasterVerve wrote: »
    I haven't watched these yet but they're generating some buzz:
    And if you're interested in those Baker & Bitter's Human Performance Outliers Podcast might interest you.

    I just listened to #176 with Norton and D'Agostino. Really good! I wish they could have gone on longer, and it was three hours as it was!
  • psuLemon
    psuLemon Posts: 38,426 MFP Moderator
    nvmomketo wrote: »
    E
    AlabasterVerve wrote: »
    I haven't watched these yet but they're generating some buzz:
    And if you're interested in those Baker & Bitter's Human Performance Outliers Podcast might interest you.

    I just listened to #176 with Norton and D'Agostino. Really good! I wish they could have gone on longer, and it was three hours as it was!

    Holy crap, 3 hours... And i was really interested up until that point.

    Is there cliff notes? Lol.
  • nvmomketo
    nvmomketo Posts: 12,019 Member
    psuLemon wrote: »
    nvmomketo wrote: »
    E
    AlabasterVerve wrote: »
    I haven't watched these yet but they're generating some buzz:
    And if you're interested in those Baker & Bitter's Human Performance Outliers Podcast might interest you.

    I just listened to #176 with Norton and D'Agostino. Really good! I wish they could have gone on longer, and it was three hours as it was!

    Holy crap, 3 hours... And i was really interested up until that point.

    Is there cliff notes? Lol.

    No kidding. It was my background noise for a couple of days. Lol
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    I've been meaning to listen to them all but I haven't got around to it yet. I'll be sure to check out Norton & D'Agostino's now at least since you liked that one!
  • nvmomketo
    nvmomketo Posts: 12,019 Member
    I started on the other one but did not get far. Being close to the opposite of a vegetarian, it held my interest less. ;) I'll try again another day.
  • nvmomketo
    nvmomketo Posts: 12,019 Member
    edited October 2018
    AlabasterVerve wrote: »
    I haven't watched these yet but they're generating some buzz:
    And if you're interested in those Baker & Bitter's Human Performance Outliers Podcast might interest you.

    This is a break down of the debate by Masterjohn, whose work was briefly discussed in the debate (shared in the LowCarberDaily by a science minded member.) I found it interesting, although I am biased in that I feel that including animal products are superior in achieving better health through diet than a vegan or vegetarian diet is, so others might not agree with him.

    I may try listening to Rogan's show again. I tried before but Kahn's prattling and Kessler's lack of emotion was hard to listen too. YMMV

    https://www.youtube.com/watch?v=-EQg6c5D3r8
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    Thanks for that @nvmomketo I couldn't listen to the vegan one either - nothing of interest there for me.

    Effect of low carbohydrate high fat diet on ldl cholesterol and gene expression in normal-weight, young adults: A randomized controlled study

    There was a significant increase in apolipoprotein B, total cholesterol, high-density lipoprotein cholesterol, free fatty acids, uric acid and urea in the LCHF group versus controls. Plasma levels of triglycerides, lipoprotein (a), glucose, C-peptide or C-reactive protein (CRP), blood pressure, body weight or body composition did not differ between the groups. PBMC gene expression of sterol regulator element binding protein 1 (SREBP-1) was increased in the LCHF group versus controls (p ≤ 0.01). The individual increase in LDL-C from baseline varied between 5 and 107% in the LCHF group.

    Source via Eric Arnesen
  • GaleHawkins
    GaleHawkins Posts: 8,159 Member
    I just watched #1176 for the FULL 3 hours. Joe Rogan is awesome. The brain of Dom D'Agostino came quietly shining through when given mike time. I was impressed by Layne Norton's ability to explain how and why the Leaky Gut Syndrome can be a health concern. It seems like Joe and Dom made headway towards getting Layne to try Keto of several months at some point in time. Layne is going to have a chapter on the Keto WOE in his new book he said. While currently he is not pro keto neither is he opposed to if it it works for others. It is amazing how many big names are doing Keto or at least speaking about the pros of keto. Dom talked about the keto cookies, breads, etc coming to the marketplace. Most everyone wants to get on the Keto bandwagon it seems because of the money there even if not fully sold like Dom.

    It was worth the 3 hours and very helpful in better understanding Layne's influence on his followers.
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
  • GaleHawkins
    GaleHawkins Posts: 8,159 Member
    AlabasterVerve wrote: »

    @AlabasterVerve thanks for sharing this awesome link about the power ketones in the body and specifically in the brain.
  • psuLemon
    psuLemon Posts: 38,426 MFP Moderator
    psuLemon wrote: »
    nvmomketo wrote: »
    E
    AlabasterVerve wrote: »
    I haven't watched these yet but they're generating some buzz:
    And if you're interested in those Baker & Bitter's Human Performance Outliers Podcast might interest you.

    I just listened to #176 with Norton and D'Agostino. Really good! I wish they could have gone on longer, and it was three hours as it was!

    Holy crap, 3 hours... And i was really interested up until that point.

    Is there cliff notes? Lol.

    So i finally had time to listen to Layne and Dom. It was really good. Found some of the stuff about set point (and adaptive thermogenesis) pretty interesting.

    Also, i thought the discussion around thr carnivore diet a little interesting, especially since both of agree on the importance of veggies.
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    Seems timely.

    Ketogenic Ratio Determines Metabolic Effects of Macronutrients and Prevents Interpretive Bias

    Source via George Henderson
  • nvmomketo
    nvmomketo Posts: 12,019 Member
    Nice. Hopefully future researchers will apply that when designing studies to test low carb or Keto on health.
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    I didn't link to this here (because it was clearly BS) but it popped up in the forums in the latest outbreak of low-carb-will-kill-you posts so it's worth mentioning the retraction due to "concerns with data integrity and an undisclosed conflict of interest by the lead author". Source
  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member

  • AlabasterVerve
    AlabasterVerve Posts: 3,171 Member
    Zach Bitter (low carb athlete) set the record for the fastest recorded 100 mile trail run. (12:08:36)

    "It kind of starts a week out for a goal race. First 4-5 days of week I go very low carb. 1-2 days out I bring back some carbs; usually in the form of potatoes, raw honey, melons berries. Race day I rely on body fat for fat burning energy and gradually use small amounts of carbs through the race." -Zach Bitter

    Source

  • Sabine_Stroehm
    Sabine_Stroehm Posts: 19,263 Member
    AlabasterVerve wrote: »
    Re: Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

    Medium: Major Study Supports Carbohydrate-Insulin Model of Obesity
    by David Ludwig

    Source

    Related critique by Hall via Freedhoff

    Fascinating study. I was going to post it myself.
    Thanks.
  • psuLemon
    psuLemon Posts: 38,426 MFP Moderator
    nvmomketo wrote: »
    Creative study.

    I found it interesting because I am one of those people who tend to magically lose weight, or manage weight with ease, when I switch to low carb diets. When I eat 1500 kcal a day, I can lose 2-3 lbs a week which translates into a TDEE of about 2500kcal. If I eat more carbs I gain at 2500 though. This could explain my experiences somewhat... I am someone who had slightly elevated insulin (prediabetic) too and it appears it could apply more to people like me.

    I'm looking forward to more studies on this.

    And i am the opposite.. when i cut fat, i do so much better, which sucks a but because i love quality cheese and guacamole. It might help that i am insulin sensitive and you are insulin resistant.

    Here is a good meta-analysis comparing the two diets.

    https://examine.com/nutrition/low-fat-vs-low-carb-for-weight-loss/
  • AnvilHead
    AnvilHead Posts: 18,343 Member
    Peer-reviewed case study: Long-term LCHF Diet Impairs Performance and Subjective Well-Being in a World Class Vegetarian Long-Distance Triathlete:

    https://journals.humankinetics.com/doi/full/10.1123/ijsnem.2018-0124
  • psychod787
    psychod787 Posts: 4,099 Member
    nvmomketo wrote: »
    Creative study.

    I found it interesting because I am one of those people who tend to magically lose weight, or manage weight with ease, when I switch to low carb diets. When I eat 1500 kcal a day, I can lose 2-3 lbs a week which translates into a TDEE of about 2500kcal. If I eat more carbs I gain at 2500 though. This could explain my experiences somewhat... I am someone who had slightly elevated insulin (prediabetic) too and it appears it could apply more to people like me.

    I'm looking forward to more studies on this.

    In am truly interested in the study, but in think Kevin Hall pokes a few holes in it. Basically the body burns calories differently after weight loss when shifting fuel sources. I run a moderate carb, 40% range, and the study is true, I do get a slight bump. I just can't go 20% carbs. Volume fills me up, not fat.

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